364 related articles for article (PubMed ID: 26059361)
1. Longevity Pathways (mTOR, SIRT, Insulin/IGF-1) as Key Modulatory Targets on Aging and Neurodegeneration.
Mazucanti CH; Cabral-Costa JV; Vasconcelos AR; Andreotti DZ; Scavone C; Kawamoto EM
Curr Top Med Chem; 2015; 15(21):2116-38. PubMed ID: 26059361
[TBL] [Abstract][Full Text] [Related]
2. Antioxidant Modulation of mTOR and Sirtuin Pathways in Age-Related Neurodegenerative Diseases.
Abdullah A; Mohd Murshid N; Makpol S
Mol Neurobiol; 2020 Dec; 57(12):5193-5207. PubMed ID: 32865663
[TBL] [Abstract][Full Text] [Related]
3. Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake.
Sharples AP; Hughes DC; Deane CS; Saini A; Selman C; Stewart CE
Aging Cell; 2015 Aug; 14(4):511-23. PubMed ID: 25866088
[TBL] [Abstract][Full Text] [Related]
4. Key proteins and pathways that regulate lifespan.
Pan H; Finkel T
J Biol Chem; 2017 Apr; 292(16):6452-6460. PubMed ID: 28264931
[TBL] [Abstract][Full Text] [Related]
5. Macronutrients and caloric intake in health and longevity.
Solon-Biet SM; Mitchell SJ; de Cabo R; Raubenheimer D; Le Couteur DG; Simpson SJ
J Endocrinol; 2015 Jul; 226(1):R17-28. PubMed ID: 26021555
[TBL] [Abstract][Full Text] [Related]
6. mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy.
Perluigi M; Di Domenico F; Butterfield DA
Neurobiol Dis; 2015 Dec; 84():39-49. PubMed ID: 25796566
[TBL] [Abstract][Full Text] [Related]
7. Caloric restriction: is mammalian life extension linked to p53?
Tucci P
Aging (Albany NY); 2012 Aug; 4(8):525-34. PubMed ID: 22983298
[TBL] [Abstract][Full Text] [Related]
8. Nutrient Sensing, Signaling and Ageing: The Role of IGF-1 and mTOR in Ageing and Age-Related Disease.
Johnson SC
Subcell Biochem; 2018; 90():49-97. PubMed ID: 30779006
[TBL] [Abstract][Full Text] [Related]
9. Conservative growth hormone/IGF-1 and mTOR signaling pathways as a target for aging and cancer prevention: do we really have an antiaging drug?
Anisimov VN
Interdiscip Top Gerontol; 2015; 40():177-88. PubMed ID: 25341521
[TBL] [Abstract][Full Text] [Related]
10. Conserved signaling pathways genetically associated with longevity across the species.
Khan AH; Zou Z; Xiang Y; Chen S; Tian XL
Biochim Biophys Acta Mol Basis Dis; 2019 Jul; 1865(7):1745-1755. PubMed ID: 31109448
[TBL] [Abstract][Full Text] [Related]
11. PI3-kinase/Akt/mTOR signaling: impaired on/off switches in aging, cognitive decline and Alzheimer's disease.
O' Neill C
Exp Gerontol; 2013 Jul; 48(7):647-53. PubMed ID: 23470275
[TBL] [Abstract][Full Text] [Related]
12. The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster.
Altintas O; Park S; Lee SJ
BMB Rep; 2016 Feb; 49(2):81-92. PubMed ID: 26698870
[TBL] [Abstract][Full Text] [Related]
13. The insulin paradox: aging, proteotoxicity and neurodegeneration.
Cohen E; Dillin A
Nat Rev Neurosci; 2008 Oct; 9(10):759-67. PubMed ID: 18769445
[TBL] [Abstract][Full Text] [Related]
14. Regulation of reproduction and longevity by nutrient-sensing pathways.
Templeman NM; Murphy CT
J Cell Biol; 2018 Jan; 217(1):93-106. PubMed ID: 29074705
[TBL] [Abstract][Full Text] [Related]
15. Heat shock factor 1 mediates the longevity conferred by inhibition of TOR and insulin/IGF-1 signaling pathways in C. elegans.
Seo K; Choi E; Lee D; Jeong DE; Jang SK; Lee SJ
Aging Cell; 2013 Dec; 12(6):1073-81. PubMed ID: 23879233
[TBL] [Abstract][Full Text] [Related]
16. Aging and age-related diseases--from endocrine therapy to target therapy.
Bao Q; Pan J; Qi H; Wang L; Qian H; Jiang F; Shao Z; Xu F; Tao Z; Ma Q; Nelson P; Hu X
Mol Cell Endocrinol; 2014 Aug; 394(1-2):115-8. PubMed ID: 25038521
[TBL] [Abstract][Full Text] [Related]
17. Igf-I signaling and effects on longevity.
Holzenberger M
Nestle Nutr Workshop Ser Pediatr Program; 2011; 68():237-45; discussion 246-9. PubMed ID: 22044904
[TBL] [Abstract][Full Text] [Related]
18. SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans.
Neumann-Haefelin E; Qi W; Finkbeiner E; Walz G; Baumeister R; Hertweck M
Genes Dev; 2008 Oct; 22(19):2721-35. PubMed ID: 18832074
[TBL] [Abstract][Full Text] [Related]
19. mTOR is a key modulator of ageing and age-related disease.
Johnson SC; Rabinovitch PS; Kaeberlein M
Nature; 2013 Jan; 493(7432):338-45. PubMed ID: 23325216
[TBL] [Abstract][Full Text] [Related]
20. Targeting mTOR signaling by polyphenols: A new therapeutic target for ageing.
Pazoki-Toroudi H; Amani H; Ajami M; Nabavi SF; Braidy N; Kasi PD; Nabavi SM
Ageing Res Rev; 2016 Nov; 31():55-66. PubMed ID: 27453478
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
