These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
200 related articles for article (PubMed ID: 26059440)
1. Maritoclax and dinaciclib inhibit MCL-1 activity and induce apoptosis in both a MCL-1-dependent and -independent manner. Varadarajan S; Poornima P; Milani M; Gowda K; Amin S; Wang HG; Cohen GM Oncotarget; 2015 May; 6(14):12668-81. PubMed ID: 26059440 [TBL] [Abstract][Full Text] [Related]
2. Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells. Pandey MK; Gowda K; Doi K; Sharma AK; Wang HG; Amin S PLoS One; 2013; 8(11):e78570. PubMed ID: 24223823 [TBL] [Abstract][Full Text] [Related]
3. Maritoclax induces apoptosis in acute myeloid leukemia cells with elevated Mcl-1 expression. Doi K; Liu Q; Gowda K; Barth BM; Claxton D; Amin S; Loughran TP; Wang HG Cancer Biol Ther; 2014 Aug; 15(8):1077-86. PubMed ID: 24842334 [TBL] [Abstract][Full Text] [Related]
5. Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy. Inoue-Yamauchi A; Jeng PS; Kim K; Chen HC; Han S; Ganesan YT; Ishizawa K; Jebiwott S; Dong Y; Pietanza MC; Hellmann MD; Kris MG; Hsieh JJ; Cheng EH Nat Commun; 2017 Jul; 8():16078. PubMed ID: 28714472 [TBL] [Abstract][Full Text] [Related]
6. Dinaciclib potently suppresses MCL-1 and selectively induces the cell death in human iPS cells without affecting the viability of cardiac tissue. Alsayegh K; Matsuura K; Sekine H; Shimizu T Sci Rep; 2017 Mar; 7():45577. PubMed ID: 28361959 [TBL] [Abstract][Full Text] [Related]
7. Pyoluteorin derivatives induce Mcl-1 degradation and apoptosis in hematological cancer cells. Doi K; Gowda K; Liu Q; Lin JM; Sung SS; Dower C; Claxton D; Loughran TP; Amin S; Wang HG Cancer Biol Ther; 2014; 15(12):1688-99. PubMed ID: 25535900 [TBL] [Abstract][Full Text] [Related]
8. The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia. Baker A; Gregory GP; Verbrugge I; Kats L; Hilton JJ; Vidacs E; Lee EM; Lock RB; Zuber J; Shortt J; Johnstone RW Cancer Res; 2016 Mar; 76(5):1158-69. PubMed ID: 26627013 [TBL] [Abstract][Full Text] [Related]
9. Sabutoclax (BI97C1) and BI112D1, putative inhibitors of MCL-1, induce mitochondrial fragmentation either upstream of or independent of apoptosis. Varadarajan S; Butterworth M; Wei J; Pellecchia M; Dinsdale D; Cohen GM Neoplasia; 2013 May; 15(5):568-78. PubMed ID: 23633928 [TBL] [Abstract][Full Text] [Related]
10. Mitochondrial dysfunction RAD51, and Ku80 proteolysis promote apoptotic effects of Dinaciclib in Bcl-xL silenced cells. Premkumar DR; Jane EP; Thambireddy S; Sutera PA; Cavaleri JM; Pollack IF Mol Carcinog; 2018 Apr; 57(4):469-482. PubMed ID: 29240261 [TBL] [Abstract][Full Text] [Related]
11. DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis. Milani M; Byrne DP; Greaves G; Butterworth M; Cohen GM; Eyers PA; Varadarajan S Cell Death Dis; 2017 Jan; 8(1):e2552. PubMed ID: 28079887 [TBL] [Abstract][Full Text] [Related]
12. Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation. Doi K; Li R; Sung SS; Wu H; Liu Y; Manieri W; Krishnegowda G; Awwad A; Dewey A; Liu X; Amin S; Cheng C; Qin Y; Schonbrunn E; Daughdrill G; Loughran TP; Sebti S; Wang HG J Biol Chem; 2012 Mar; 287(13):10224-10235. PubMed ID: 22311987 [TBL] [Abstract][Full Text] [Related]
13. MCL1 and BCL-xL levels in solid tumors are predictive of dinaciclib-induced apoptosis. Booher RN; Hatch H; Dolinski BM; Nguyen T; Harmonay L; Al-Assaad AS; Ayers M; Nebozhyn M; Loboda A; Hirsch HA; Zhang T; Shi B; Merkel CE; Angagaw MH; Wang Y; Long BJ; Lennon XQ; Miselis N; Pucci V; Monahan JW; Lee J; Kondic AG; Im EK; Mauro D; Blanchard R; Gilliland G; Fawell SE; Zawel L; Schuller AG; Strack P PLoS One; 2014; 9(10):e108371. PubMed ID: 25289887 [TBL] [Abstract][Full Text] [Related]
14. The anti-melanoma activity of dinaciclib, a cyclin-dependent kinase inhibitor, is dependent on p53 signaling. Desai BM; Villanueva J; Nguyen TT; Lioni M; Xiao M; Kong J; Krepler C; Vultur A; Flaherty KT; Nathanson KL; Smalley KS; Herlyn M PLoS One; 2013; 8(3):e59588. PubMed ID: 23527225 [TBL] [Abstract][Full Text] [Related]
15. Norcantharidin enhances ABT-737-induced apoptosis in hepatocellular carcinoma cells by transcriptional repression of Mcl-1. Zhang S; Li G; Ma X; Wang Y; Liu G; Feng L; Zhao Y; Zhang G; Wu Y; Ye X; Qin B; Lu J Cell Signal; 2012 Sep; 24(9):1803-9. PubMed ID: 22609455 [TBL] [Abstract][Full Text] [Related]
16. Dinaciclib, a Cyclin-Dependent Kinase Inhibitor Promotes Proteasomal Degradation of Mcl-1 and Enhances ABT-737-Mediated Cell Death in Malignant Human Glioma Cell Lines. Jane EP; Premkumar DR; Cavaleri JM; Sutera PA; Rajasekar T; Pollack IF J Pharmacol Exp Ther; 2016 Feb; 356(2):354-65. PubMed ID: 26585571 [TBL] [Abstract][Full Text] [Related]
17. Evaluation and critical assessment of putative MCL-1 inhibitors. Varadarajan S; Vogler M; Butterworth M; Dinsdale D; Walensky LD; Cohen GM Cell Death Differ; 2013 Nov; 20(11):1475-84. PubMed ID: 23832116 [TBL] [Abstract][Full Text] [Related]
18. Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors. Floros KV; Jacob S; Kurupi R; Fairchild CK; Hu B; Puchalapalli M; E Koblinski J; Dozmorov MG; Boikos SA; Scaltriti M; Faber AC Cell Death Dis; 2021 Feb; 12(2):179. PubMed ID: 33589591 [TBL] [Abstract][Full Text] [Related]
19. A cyclin-dependent kinase inhibitor, dinaciclib in preclinical treatment models of thyroid cancer. Lin SF; Lin JD; Hsueh C; Chou TC; Wong RJ PLoS One; 2017; 12(2):e0172315. PubMed ID: 28207834 [TBL] [Abstract][Full Text] [Related]
20. Cyclin-dependent kinase inhibitor dinaciclib potently synergizes with cisplatin in preclinical models of ovarian cancer. Chen XX; Xie FF; Zhu XJ; Lin F; Pan SS; Gong LH; Qiu JG; Zhang WJ; Jiang QW; Mei XL; Xue YQ; Qin WM; Shi Z; Yan XJ Oncotarget; 2015 Jun; 6(17):14926-39. PubMed ID: 25962959 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]