These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

313 related articles for article (PubMed ID: 26061183)

  • 1. Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody-Drug Conjugates.
    van Geel R; Wijdeven MA; Heesbeen R; Verkade JM; Wasiel AA; van Berkel SS; van Delft FL
    Bioconjug Chem; 2015 Nov; 26(11):2233-42. PubMed ID: 26061183
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sortase Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody Drug Conjugates with High In Vitro and In Vivo Potency.
    Beerli RR; Hell T; Merkel AS; Grawunder U
    PLoS One; 2015; 10(7):e0131177. PubMed ID: 26132162
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Homogeneous Antibody-Drug Conjugates via Glycoengineering.
    Tang F; Shi W; Huang W
    Methods Mol Biol; 2019; 2033():221-238. PubMed ID: 31332757
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Highly Potent, Anthracycline-based Antibody-Drug Conjugates Generated by Enzymatic, Site-specific Conjugation.
    Stefan N; Gébleux R; Waldmeier L; Hell T; Escher M; Wolter FI; Grawunder U; Beerli RR
    Mol Cancer Ther; 2017 May; 16(5):879-892. PubMed ID: 28258164
    [TBL] [Abstract][Full Text] [Related]  

  • 5. One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody-Drug Conjugates through Site-Specific Chemoenzymatic Glycan Remodeling.
    Ou C; Li C; Zhang R; Yang Q; Zong G; Dai Y; Francis RL; Bournazos S; Ravetch JV; Wang LX
    Bioconjug Chem; 2021 Aug; 32(8):1888-1897. PubMed ID: 34351736
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antibody Conjugations via Glycosyl Remodeling.
    Toftevall H; Nyhlén H; Olsson F; Sjögren J
    Methods Mol Biol; 2020; 2078():131-145. PubMed ID: 31643054
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody-Drug Conjugates Using Click Cycloaddition Chemistry.
    VanBrunt MP; Shanebeck K; Caldwell Z; Johnson J; Thompson P; Martin T; Dong H; Li G; Xu H; D'Hooge F; Masterson L; Bariola P; Tiberghien A; Ezeadi E; Williams DG; Hartley JA; Howard PW; Grabstein KH; Bowen MA; Marelli M
    Bioconjug Chem; 2015 Nov; 26(11):2249-60. PubMed ID: 26332743
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enzymatic glycan remodeling-metal free click (GlycoConnect™) provides homogenous antibody-drug conjugates with improved stability and therapeutic index without sequence engineering.
    Wijdeven MA; van Geel R; Hoogenboom JH; Verkade JMM; Janssen BMG; Hurkmans I; de Bever L; van Berkel SS; van Delft FL
    MAbs; 2022; 14(1):2078466. PubMed ID: 35634725
    [TBL] [Abstract][Full Text] [Related]  

  • 9. General and Robust Chemoenzymatic Method for Glycan-Mediated Site-Specific Labeling and Conjugation of Antibodies: Facile Synthesis of Homogeneous Antibody-Drug Conjugates.
    Zhang X; Ou C; Liu H; Prabhu SK; Li C; Yang Q; Wang LX
    ACS Chem Biol; 2021 Nov; 16(11):2502-2514. PubMed ID: 34569782
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chemoenzymatic glycan labelling as a platform for site-specific IgM-antibody drug conjugates.
    Moh ESX; Sayyadi N; Packer NH
    Anal Biochem; 2019 Nov; 584():113385. PubMed ID: 31381874
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of cysteine-linked conjugation profiles of immunoglobulin G1 and immunoglobulin G2 antibody-drug conjugates.
    Wiggins B; Liu-Shin L; Yamaguchi H; Ratnaswamy G
    J Pharm Sci; 2015 Apr; 104(4):1362-72. PubMed ID: 25631158
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glycans of Antibodies as a Specific Site for Drug Conjugation Using Glycosyltransferases.
    Qasba PK
    Bioconjug Chem; 2015 Nov; 26(11):2170-5. PubMed ID: 26065635
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biophysical Properties and Heating-Induced Aggregation of Lysine-Conjugated Antibody-Drug Conjugates.
    Gandhi AV; Arlotta KJ; Chen HN; Owen SC; Carpenter JF
    J Pharm Sci; 2018 Jul; 107(7):1858-1869. PubMed ID: 29626535
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of Antibody Products Obtained through Enzymatic and Nonenzymatic Glycosylation Reactions with a Glycan Oxazoline and Preparation of a Homogeneous Antibody-Drug Conjugate via Fc N-Glycan.
    Manabe S; Yamaguchi Y; Matsumoto K; Fuchigami H; Kawase T; Hirose K; Mitani A; Sumiyoshi W; Kinoshita T; Abe J; Yasunaga M; Matsumura Y; Ito Y
    Bioconjug Chem; 2019 May; 30(5):1343-1355. PubMed ID: 30938513
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ez-ADiCon: A novel glyco-remodeling based strategy that enables preparation of homogenous antibody-drug conjugates via one-step enzymatic transglycosylation with payload-preloaded bi-antennary glycan complexes.
    Chon H; Kanamori S; Hibino K; Nagahara T; Suzuki T; Ohara K; Narumi H
    Bioorg Med Chem Lett; 2023 Jan; 80():129117. PubMed ID: 36584791
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Conjugation site analysis of antibody-drug-conjugates (ADCs) by signature ion fingerprinting and normalized area quantitation approach using nano-liquid chromatography coupled to high resolution mass spectrometry.
    Sang H; Lu G; Liu Y; Hu Q; Xing W; Cui D; Zhou F; Zhang J; Hao H; Wang G; Ye H
    Anal Chim Acta; 2017 Feb; 955():67-78. PubMed ID: 28088282
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system.
    Zimmerman ES; Heibeck TH; Gill A; Li X; Murray CJ; Madlansacay MR; Tran C; Uter NT; Yin G; Rivers PJ; Yam AY; Wang WD; Steiner AR; Bajad SU; Penta K; Yang W; Hallam TJ; Thanos CD; Sato AK
    Bioconjug Chem; 2014 Feb; 25(2):351-61. PubMed ID: 24437342
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Arginine-selective bioconjugation with 4-azidophenyl glyoxal: application to the single and dual functionalisation of native antibodies.
    Dovgan I; Erb S; Hessmann S; Ursuegui S; Michel C; Muller C; Chaubet G; Cianférani S; Wagner A
    Org Biomol Chem; 2018 Feb; 16(8):1305-1311. PubMed ID: 29388667
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities.
    Kurogochi M; Mori M; Osumi K; Tojino M; Sugawara S; Takashima S; Hirose Y; Tsukimura W; Mizuno M; Amano J; Matsuda A; Tomita M; Takayanagi A; Shoda S; Shirai T
    PLoS One; 2015; 10(7):e0132848. PubMed ID: 26200113
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity through linker and antibody engineering.
    Pillow TH; Tien J; Parsons-Reponte KL; Bhakta S; Li H; Staben LR; Li G; Chuh J; Fourie-O'Donohue A; Darwish M; Yip V; Liu L; Leipold DD; Su D; Wu E; Spencer SD; Shen BQ; Xu K; Kozak KR; Raab H; Vandlen R; Lewis Phillips GD; Scheller RH; Polakis P; Sliwkowski MX; Flygare JA; Junutula JR
    J Med Chem; 2014 Oct; 57(19):7890-9. PubMed ID: 25191794
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.