BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 26066325)

  • 1. iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis.
    Mateos J; Landeira-Abia A; Fafián-Labora JA; Fernández-Pernas P; Lesende-Rodríguez I; Fernández-Puente P; Fernández-Moreno M; Delmiro A; Martín MA; Blanco FJ; Arufe MC
    Stem Cell Res Ther; 2015 Jun; 6(1):119. PubMed ID: 26066325
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lamin A deregulation in human mesenchymal stem cells promotes an impairment in their chondrogenic potential and imbalance in their response to oxidative stress.
    Mateos J; De la Fuente A; Lesende-Rodriguez I; Fernández-Pernas P; Arufe MC; Blanco FJ
    Stem Cell Res; 2013 Nov; 11(3):1137-48. PubMed ID: 23994728
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sustained accumulation of prelamin A and depletion of lamin A/C both cause oxidative stress and mitochondrial dysfunction but induce different cell fates.
    Sieprath T; Corne TD; Nooteboom M; Grootaert C; Rajkovic A; Buysschaert B; Robijns J; Broers JL; Ramaekers FC; Koopman WJ; Willems PH; De Vos WH
    Nucleus; 2015; 6(3):236-46. PubMed ID: 25996284
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment.
    Villa-Bellosta R; Rivera-Torres J; Osorio FG; Acín-Pérez R; Enriquez JA; López-Otín C; Andrés V
    Circulation; 2013 Jun; 127(24):2442-51. PubMed ID: 23690466
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition.
    Glynn MW; Glover TW
    Hum Mol Genet; 2005 Oct; 14(20):2959-69. PubMed ID: 16126733
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Epigenetic involvement in Hutchinson-Gilford progeria syndrome: a mini-review.
    Arancio W; Pizzolanti G; Genovese SI; Pitrone M; Giordano C
    Gerontology; 2014; 60(3):197-203. PubMed ID: 24603298
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The truncated prelamin A in Hutchinson-Gilford progeria syndrome alters segregation of A-type and B-type lamin homopolymers.
    Delbarre E; Tramier M; Coppey-Moisan M; Gaillard C; Courvalin JC; Buendia B
    Hum Mol Genet; 2006 Apr; 15(7):1113-22. PubMed ID: 16481358
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A conserved splicing mechanism of the LMNA gene controls premature aging.
    Lopez-Mejia IC; Vautrot V; De Toledo M; Behm-Ansmant I; Bourgeois CF; Navarro CL; Osorio FG; Freije JM; Stévenin J; De Sandre-Giovannoli A; Lopez-Otin C; Lévy N; Branlant C; Tazi J
    Hum Mol Genet; 2011 Dec; 20(23):4540-55. PubMed ID: 21875900
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nuclear stiffening and chromatin softening with progerin expression leads to an attenuated nuclear response to force.
    Booth EA; Spagnol ST; Alcoser TA; Dahl KN
    Soft Matter; 2015 Aug; 11(32):6412-8. PubMed ID: 26171741
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hutchinson-Gilford progeria syndrome through the lens of transcription.
    Prokocimer M; Barkan R; Gruenbaum Y
    Aging Cell; 2013 Aug; 12(4):533-43. PubMed ID: 23496208
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alteration of splice site selection in the LMNA gene and inhibition of progerin production via AMPK activation.
    Finley J
    Med Hypotheses; 2014 Nov; 83(5):580-7. PubMed ID: 25216752
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Towards a Drosophila model of Hutchinson-Gilford progeria syndrome.
    Beard GS; Bridger JM; Kill IR; Tree DR
    Biochem Soc Trans; 2008 Dec; 36(Pt 6):1389-92. PubMed ID: 19021561
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proteomic analysis of mitochondria from senescent Podospora anserina casts new light on ROS dependent aging mechanisms.
    Plohnke N; Hamann A; Poetsch A; Osiewacz HD; Rögner M; Rexroth S
    Exp Gerontol; 2014 Aug; 56():13-25. PubMed ID: 24556281
    [TBL] [Abstract][Full Text] [Related]  

  • 14. High-Throughput Screen Detects Calcium Signaling Dysfunction in Hutchinson-Gilford Progeria Syndrome.
    Fafián-Labora JA; Morente-López M; de Toro FJ; Arufe MC
    Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34298947
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes.
    Costa VM; Silva R; Tavares LC; Vitorino R; Amado F; Carvalho F; Bastos Mde L; Carvalho M; Carvalho RA; Remião F
    Toxicology; 2009 Jun; 260(1-3):84-96. PubMed ID: 19464573
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Amphibian oocyte nuclei expressing lamin A with the progeria mutation E145K exhibit an increased elastic modulus.
    Kaufmann A; Heinemann F; Radmacher M; Stick R
    Nucleus; 2011; 2(4):310-9. PubMed ID: 21941106
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production.
    Kim Y; Kim YS; Kim DE; Lee JS; Song JH; Kim HG; Cho DH; Jeong SY; Jin DH; Jang SJ; Seol HS; Suh YA; Lee SJ; Kim CS; Koh JY; Hwang JJ
    Autophagy; 2013 Dec; 9(12):2126-39. PubMed ID: 24322755
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment.
    Columbaro M; Capanni C; Mattioli E; Novelli G; Parnaik VK; Squarzoni S; Maraldi NM; Lattanzi G
    Cell Mol Life Sci; 2005 Nov; 62(22):2669-78. PubMed ID: 16261260
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quantitative analysis of localization and nuclear aggregate formation induced by GFP-lamin A mutant proteins in living HeLa cells.
    Hübner S; Eam JE; Wagstaff KM; Jans DA
    J Cell Biochem; 2006 Jul; 98(4):810-26. PubMed ID: 16440304
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Atherosclerosis in ancient humans, accelerated aging syndromes and normal aging: is lamin a protein a common link?
    Miyamoto MI; Djabali K; Gordon LB
    Glob Heart; 2014 Jun; 9(2):211-8. PubMed ID: 25667091
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.