These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

410 related articles for article (PubMed ID: 26068752)

  • 21. The crystal structure of Cpf1 in complex with CRISPR RNA.
    Dong D; Ren K; Qiu X; Zheng J; Guo M; Guan X; Liu H; Li N; Zhang B; Yang D; Ma C; Wang S; Wu D; Ma Y; Fan S; Wang J; Gao N; Huang Z
    Nature; 2016 Apr; 532(7600):522-6. PubMed ID: 27096363
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
    Jinek M; Chylinski K; Fonfara I; Hauer M; Doudna JA; Charpentier E
    Science; 2012 Aug; 337(6096):816-21. PubMed ID: 22745249
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence.
    Babu K; Kathiresan V; Kumari P; Newsom S; Parameshwaran HP; Chen X; Liu J; Qin PZ; Rajan R
    Biochemistry; 2021 Dec; 60(49):3783-3800. PubMed ID: 34757726
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Chimeric Guides Probe and Enhance Cas9 Biochemical Activity.
    Kartje ZJ; Barkau CL; Rohilla KJ; Ageely EA; Gagnon KT
    Biochemistry; 2018 May; 57(21):3027-3031. PubMed ID: 29746102
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
    Jinek M; Jiang F; Taylor DW; Sternberg SH; Kaya E; Ma E; Anders C; Hauer M; Zhou K; Lin S; Kaplan M; Iavarone AT; Charpentier E; Nogales E; Doudna JA
    Science; 2014 Mar; 343(6176):1247997. PubMed ID: 24505130
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Kinetics of the CRISPR-Cas9 effector complex assembly and the role of 3'-terminal segment of guide RNA.
    Mekler V; Minakhin L; Semenova E; Kuznedelov K; Severinov K
    Nucleic Acids Res; 2016 Apr; 44(6):2837-45. PubMed ID: 26945042
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Self-assembled DNA nanoclews for the efficient delivery of CRISPR-Cas9 for genome editing.
    Sun W; Ji W; Hall JM; Hu Q; Wang C; Beisel CL; Gu Z
    Angew Chem Int Ed Engl; 2015 Oct; 54(41):12029-33. PubMed ID: 26310292
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Improving CRISPR-Cas nuclease specificity using truncated guide RNAs.
    Fu Y; Sander JD; Reyon D; Cascio VM; Joung JK
    Nat Biotechnol; 2014 Mar; 32(3):279-284. PubMed ID: 24463574
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA.
    Alcón P; Montoya G; Stella S
    Acta Crystallogr F Struct Biol Commun; 2017 Jul; 73(Pt 7):409-415. PubMed ID: 28695850
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.
    Jiang F; Taylor DW; Chen JS; Kornfeld JE; Zhou K; Thompson AJ; Nogales E; Doudna JA
    Science; 2016 Feb; 351(6275):867-71. PubMed ID: 26841432
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems.
    Yamada M; Watanabe Y; Gootenberg JS; Hirano H; Ran FA; Nakane T; Ishitani R; Zhang F; Nishimasu H; Nureki O
    Mol Cell; 2017 Mar; 65(6):1109-1121.e3. PubMed ID: 28306506
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Prediction and Validation of Native and Engineered Cas9 Guide Sequences.
    Briner AE; Henriksen ED; Barrangou R
    Cold Spring Harb Protoc; 2016 Jul; 2016(7):. PubMed ID: 27371591
    [TBL] [Abstract][Full Text] [Related]  

  • 33. DNA Targeting by a Minimal CRISPR RNA-Guided Cascade.
    Hochstrasser ML; Taylor DW; Kornfeld JE; Nogales E; Doudna JA
    Mol Cell; 2016 Sep; 63(5):840-51. PubMed ID: 27588603
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Protospacer Adjacent Motif-Induced Allostery Activates CRISPR-Cas9.
    Palermo G; Ricci CG; Fernando A; Basak R; Jinek M; Rivalta I; Batista VS; McCammon JA
    J Am Chem Soc; 2017 Nov; 139(45):16028-16031. PubMed ID: 28764328
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mapping the sugar dependency for rational generation of a DNA-RNA hybrid-guided Cas9 endonuclease.
    Rueda FO; Bista M; Newton MD; Goeppert AU; Cuomo ME; Gordon E; Kröner F; Read JA; Wrigley JD; Rueda D; Taylor BJM
    Nat Commun; 2017 Nov; 8(1):1610. PubMed ID: 29151576
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Editor's cut: DNA cleavage by CRISPR RNA-guided nucleases Cas9 and Cas12a.
    Swartjes T; Staals RHJ; van der Oost J
    Biochem Soc Trans; 2020 Feb; 48(1):207-219. PubMed ID: 31872209
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Functional Insights Revealed by the Kinetic Mechanism of CRISPR/Cas9.
    Raper AT; Stephenson AA; Suo Z
    J Am Chem Soc; 2018 Feb; 140(8):2971-2984. PubMed ID: 29442507
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Incorporation of bridged nucleic acids into CRISPR RNAs improves Cas9 endonuclease specificity.
    Cromwell CR; Sung K; Park J; Krysler AR; Jovel J; Kim SK; Hubbard BP
    Nat Commun; 2018 Apr; 9(1):1448. PubMed ID: 29654299
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Crystal structure of Cas9 in complex with guide RNA and target DNA.
    Nishimasu H; Ran FA; Hsu PD; Konermann S; Shehata SI; Dohmae N; Ishitani R; Zhang F; Nureki O
    Cell; 2014 Feb; 156(5):935-49. PubMed ID: 24529477
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture.
    O'Geen H; Henry IM; Bhakta MS; Meckler JF; Segal DJ
    Nucleic Acids Res; 2015 Mar; 43(6):3389-404. PubMed ID: 25712100
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.