BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

414 related articles for article (PubMed ID: 26073084)

  • 1. Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo.
    Huang W; Dong Z; Chen Y; Wang F; Wang CJ; Peng H; He Y; Hangoc G; Pollok K; Sandusky G; Fu XY; Broxmeyer HE; Zhang ZY; Liu JY; Zhang JT
    Oncogene; 2016 Feb; 35(6):783-92. PubMed ID: 26073084
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A small molecule compound targeting STAT3 DNA-binding domain inhibits cancer cell proliferation, migration, and invasion.
    Huang W; Dong Z; Wang F; Peng H; Liu JY; Zhang JT
    ACS Chem Biol; 2014 May; 9(5):1188-96. PubMed ID: 24661007
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth.
    Li X; Ma H; Li L; Chen Y; Sun X; Dong Z; Liu JY; Zhu W; Zhang JT
    Oncogene; 2018 May; 37(18):2469-2480. PubMed ID: 29456240
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small-molecule compounds targeting the STAT3 DNA-binding domain suppress survival of cisplatin-resistant human ovarian cancer cells by inducing apoptosis.
    Huang W; Liu Y; Wang J; Yuan X; Jin HW; Zhang LR; Zhang JT; Liu ZM; Cui JR
    Eur J Med Chem; 2018 Sep; 157():887-897. PubMed ID: 30145375
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity
    Son DJ; Zheng J; Jung YY; Hwang CJ; Lee HP; Woo JR; Baek SY; Ham YW; Kang MW; Shong M; Kweon GR; Song MJ; Jung JK; Han SB; Kim BY; Yoon DY; Choi BY; Hong JT
    Theranostics; 2017; 7(18):4632-4642. PubMed ID: 29158850
    [No Abstract]   [Full Text] [Related]  

  • 6. LL1, a novel and highly selective STAT3 inhibitor, displays anti-colorectal cancer activities in vitro and in vivo.
    Liu Z; Wang H; Guan L; Lai C; Yu W; Lai M
    Br J Pharmacol; 2020 Jan; 177(2):298-313. PubMed ID: 31499589
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-based discovery of potent and selective small-molecule inhibitors targeting signal transducer and activator of transcription 3 (STAT3).
    Huang Q; Zhong Y; Li B; Ouyang S; Deng L; Mo J; Shi S; Lv N; Wu R; Liu P; Hu W; Zhang X; Wang Y
    Eur J Med Chem; 2021 Oct; 221():113525. PubMed ID: 34000483
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo.
    Bai L; Zhou H; Xu R; Zhao Y; Chinnaswamy K; McEachern D; Chen J; Yang CY; Liu Z; Wang M; Liu L; Jiang H; Wen B; Kumar P; Meagher JL; Sun D; Stuckey JA; Wang S
    Cancer Cell; 2019 Nov; 36(5):498-511.e17. PubMed ID: 31715132
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A cell-permeable Stat3 SH2 domain mimetic inhibits Stat3 activation and induces antitumor cell effects in vitro.
    Zhao W; Jaganathan S; Turkson J
    J Biol Chem; 2010 Nov; 285(46):35855-65. PubMed ID: 20807764
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.
    Siddiquee K; Zhang S; Guida WC; Blaskovich MA; Greedy B; Lawrence HR; Yip ML; Jove R; McLaughlin MM; Lawrence NJ; Sebti SM; Turkson J
    Proc Natl Acad Sci U S A; 2007 May; 104(18):7391-6. PubMed ID: 17463090
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The STAT3 Inhibitor Galiellalactone Effectively Reduces Tumor Growth and Metastatic Spread in an Orthotopic Xenograft Mouse Model of Prostate Cancer.
    Canesin G; Evans-Axelsson S; Hellsten R; Sterner O; Krzyzanowska A; Andersson T; Bjartell A
    Eur Urol; 2016 Mar; 69(3):400-4. PubMed ID: 26144873
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Small molecule inhibitors of STAT3 for cancer therapy.
    Zhao M; Jiang B; Gao FH
    Curr Med Chem; 2011; 18(26):4012-8. PubMed ID: 21824090
    [TBL] [Abstract][Full Text] [Related]  

  • 13. LYW-6, a novel cryptotanshinone derived STAT3 targeting inhibitor, suppresses colorectal cancer growth and metastasis.
    Wang H; Liu Z; Guan L; Li J; Chen S; Yu W; Lai M
    Pharmacol Res; 2020 Mar; 153():104661. PubMed ID: 31982491
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor.
    Cheng X; Liu YQ; Wang GZ; Yang LN; Lu YZ; Li XC; Zhou B; Qu LW; Wang XL; Cheng YX; Liu J; Tao SC; Zhou GB
    Oncotarget; 2017 Jan; 8(2):2681-2693. PubMed ID: 27835873
    [TBL] [Abstract][Full Text] [Related]  

  • 15. (E)-4-(3-(3,5-dimethoxyphenyl)allyl)-2-methoxyphenol inhibits growth of colon tumors in mice.
    Zheng J; Park MH; Son DJ; Choi MG; Choi JS; Nam KT; Kim HD; Rodriguez K; Gann B; Ham YW; Han SB; Hong JT
    Oncotarget; 2015 Dec; 6(39):41929-43. PubMed ID: 26474284
    [TBL] [Abstract][Full Text] [Related]  

  • 16. AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer.
    Hong D; Kurzrock R; Kim Y; Woessner R; Younes A; Nemunaitis J; Fowler N; Zhou T; Schmidt J; Jo M; Lee SJ; Yamashita M; Hughes SG; Fayad L; Piha-Paul S; Nadella MV; Mohseni M; Lawson D; Reimer C; Blakey DC; Xiao X; Hsu J; Revenko A; Monia BP; MacLeod AR
    Sci Transl Med; 2015 Nov; 7(314):314ra185. PubMed ID: 26582900
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling.
    Zhu F; Dai C; Fu Y; Loo JF; Xia D; Gao SP; Ma Z; Chen Z
    Oncotarget; 2016 Feb; 7(8):9462-76. PubMed ID: 26843613
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antitumor activity of a novel oral signal transducer and activator of transcription 3 inhibitor YHO-1701.
    Nishisaka F; Taniguchi K; Tsugane M; Hirata G; Takagi A; Asakawa N; Kurita A; Takahashi H; Ogo N; Shishido Y; Asai A
    Cancer Sci; 2020 May; 111(5):1774-1784. PubMed ID: 32112605
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
    Furtek SL; Backos DS; Matheson CJ; Reigan P
    ACS Chem Biol; 2016 Feb; 11(2):308-18. PubMed ID: 26730496
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Signal Transducer and Activator of Transcription Protein 3 (STAT3): An Update on its Direct Inhibitors as Promising Anticancer Agents.
    Gelain A; Mori M; Meneghetti F; Villa S
    Curr Med Chem; 2019; 26(27):5165-5206. PubMed ID: 30027840
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.