These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

107 related articles for article (PubMed ID: 26076991)

  • 1. Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence.
    Chu J; Li JG; Hoffman NE; Stough AM; Madesh M; Praticò D
    Sci Rep; 2015 Jun; 5():11086. PubMed ID: 26076991
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gamma secretase-activating protein is a substrate for caspase-3: implications for Alzheimer's disease.
    Chu J; Li JG; Joshi YB; Giannopoulos PF; Hoffman NE; Madesh M; Praticò D
    Biol Psychiatry; 2015 Apr; 77(8):720-8. PubMed ID: 25052851
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease.
    He G; Luo W; Li P; Remmers C; Netzer WJ; Hendrick J; Bettayeb K; Flajolet M; Gorelick F; Wennogle LP; Greengard P
    Nature; 2010 Sep; 467(7311):95-8. PubMed ID: 20811458
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Degradation of gamma secretase activating protein by the ubiquitin-proteasome pathway.
    Chu J; Li JG; Hoffman NE; Madesh M; Praticò D
    J Neurochem; 2015 May; 133(3):432-9. PubMed ID: 25533523
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of γ-secretase activating protein (GSAP) and imatinib in the regulation of γ-secretase activity and amyloid-β generation.
    Hussain I; Fabrègue J; Anderes L; Ousson S; Borlat F; Eligert V; Berger S; Dimitrov M; Alattia JR; Fraering PC; Beher D
    J Biol Chem; 2013 Jan; 288(4):2521-31. PubMed ID: 23209290
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proton myo-inositol cotransporter is a novel γ-secretase associated protein that regulates Aβ production without affecting Notch cleavage.
    Teranishi Y; Inoue M; Yamamoto NG; Kihara T; Wiehager B; Ishikawa T; Winblad B; Schedin-Weiss S; Frykman S; Tjernberg LO
    FEBS J; 2015 Sep; 282(17):3438-51. PubMed ID: 26094765
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Immunohistochemical characterization of γ-secretase activating protein expression in Alzheimer's disease brains.
    Satoh J; Tabunoki H; Ishida T; Saito Y; Arima K
    Neuropathol Appl Neurobiol; 2012 Apr; 38(2):132-41. PubMed ID: 21718343
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease.
    Firuzi O; Zhuo J; Chinnici CM; Wisniewski T; Praticò D
    FASEB J; 2008 Apr; 22(4):1169-78. PubMed ID: 17998412
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Involvement of 5-lipoxygenase activating protein in the amyloidotic phenotype of an Alzheimer's disease mouse model.
    Chu J; Praticò D
    J Neuroinflammation; 2012 Jun; 9():127. PubMed ID: 22697885
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulation of amyloid precursor protein cleavage by γ-secretase activating protein through phase separation.
    Jin C; Wang J; Wang Y; Jia B; Guo X; Yang G; Xu P; Greengard P; Zhou R; Shi Y
    Proc Natl Acad Sci U S A; 2022 Mar; 119(12):e2122292119. PubMed ID: 35298330
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice.
    Chu J; Giannopoulos PF; Ceballos-Diaz C; Golde TE; Pratico D
    Mol Neurodegener; 2012 Jan; 7(1):1. PubMed ID: 22222029
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The 5-Lipoxygenase as modulator of Alzheimer's γ-secretase and therapeutic target.
    Chu J; Praticò D
    Brain Res Bull; 2016 Sep; 126(Pt 2):207-212. PubMed ID: 27005438
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nardilysin prevents amyloid plaque formation by enhancing α-secretase activity in an Alzheimer's disease mouse model.
    Ohno M; Hiraoka Y; Lichtenthaler SF; Nishi K; Saijo S; Matsuoka T; Tomimoto H; Araki W; Takahashi R; Kita T; Kimura T; Nishi E
    Neurobiol Aging; 2014 Jan; 35(1):213-22. PubMed ID: 23954170
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GSAP modulates γ-secretase specificity by inducing conformational change in PS1.
    Wong E; Liao GP; Chang JC; Xu P; Li YM; Greengard P
    Proc Natl Acad Sci U S A; 2019 Mar; 116(13):6385-6390. PubMed ID: 30850537
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TASTPM mice expressing amyloid precursor protein and presenilin-1 mutant transgenes are sensitive to γ-secretase modulation and amyloid-β₄₂ lowering by GSM-10h.
    Hussain I; Harrison DC; Hawkins J; Chapman T; Marshall I; Facci L; Ahmed S; Brackenborough K; Skaper SD; Mead TL; Smith BB; Giblin GM; Hall A; Gonzalez MI; Richardson JC
    Neurodegener Dis; 2011; 8(1-2):15-24. PubMed ID: 20689247
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 5-lipoxygenase as an endogenous modulator of amyloid β formation in vivo.
    Chu J; Praticò D
    Ann Neurol; 2011 Jan; 69(1):34-46. PubMed ID: 21280074
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production.
    Wang J; Lu R; Yang J; Li H; He Z; Jing N; Wang X; Wang Y
    Nat Commun; 2015 Nov; 6():8876. PubMed ID: 26581893
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modulation of lipopolysaccharide-induced memory insult, γ-secretase, and neuroinflammation in triple transgenic mice by 5-lipoxygenase.
    Joshi YB; Giannopoulos PF; Chu J; Praticò D
    Neurobiol Aging; 2014 May; 35(5):1024-31. PubMed ID: 24332986
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of Panax notoginseng saponin on α, β, and γ secretase involved in Aβ deposition in SAMP8 mice.
    Huang J; Wu D; Wang J; Li F; Lu L; Gao Y; Zhong Z
    Neuroreport; 2014 Jan; 25(2):89-93. PubMed ID: 24165110
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.