BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

488 related articles for article (PubMed ID: 26077125)

  • 1. Genetic Determinants of Methotrexate Toxicity in Tunisian Patients with Rheumatoid Arthritis: A Study of Polymorphisms Involved in the MTX Metabolic Pathway.
    Chaabane S; Marzouk S; Akrout R; Ben Hamad M; Achour Y; Rebai A; Keskes L; Fourati H; Bahloul Z; Maalej A
    Eur J Drug Metab Pharmacokinet; 2016 Aug; 41(4):385-93. PubMed ID: 26077125
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Association of hyperhomocysteinemia with genetic variants in key enzymes of homocysteine metabolism and methotrexate toxicity in rheumatoid arthritis patients.
    Chaabane S; Messedi M; Akrout R; Ben Hamad M; Turki M; Marzouk S; Keskes L; Bahloul Z; Rebai A; Ayedi F; Maalej A
    Inflamm Res; 2018 Aug; 67(8):703-710. PubMed ID: 29796841
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis.
    Kumagai K; Hiyama K; Oyama T; Maeda H; Kohno N
    Int J Mol Med; 2003 May; 11(5):593-600. PubMed ID: 12684695
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The C677T polymorphism in the MTHFR gene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population.
    Cáliz R; del Amo J; Balsa A; Blanco F; Silva L; Sanmarti R; Martínez FG; Collado MD; Ramirez Mdel C; Tejedor D; Artieda M; Pascual-Salcedo D; Oreiro N; Andreu JL; Graell E; Simon L; Martínez A; Mulero J
    Scand J Rheumatol; 2012 Feb; 41(1):10-4. PubMed ID: 22044028
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2756GG genotype of methionine synthase reductase gene is more prevalent in rheumatoid arthritis patients treated with methotrexate and is associated with methotrexate-induced nodulosis.
    Berkun Y; Abou Atta I; Rubinow A; Orbach H; Levartovsky D; Aamar S; Arbel O; Dresner-Pollak R; Friedman G; Ben-Yehuda A
    J Rheumatol; 2007 Aug; 34(8):1664-9. PubMed ID: 17611986
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism.
    Bohanec Grabar P; Logar D; Lestan B; Dolzan V
    Eur J Clin Pharmacol; 2008 Nov; 64(11):1057-68. PubMed ID: 18607581
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacogenetic polymorphisms contributing to toxicity induced by methotrexate in the southern Spanish population with rheumatoid arthritis.
    Plaza-Plaza JC; Aguilera M; Cañadas-Garre M; Chemello C; González-Utrilla A; Faus Dader MJ; Calleja MA
    OMICS; 2012 Nov; 16(11):589-95. PubMed ID: 23095111
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Methylenetetrahydrofolate reductase polymorphisms and methotrexate: no association with response to therapy nor with drug-related adverse events in an Italian population of rheumatic patients.
    Taraborelli M; Andreoli L; Archetti S; Ferrari M; Cattaneo R; Tincani A
    Clin Exp Rheumatol; 2009; 27(3):499-502. PubMed ID: 19604445
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MTRR A66G, RFC1 G80A, and MTHFR C677T and A1298C Polymorphisms and Disease Activity in Mexicans with Rheumatoid Arthritis Treated with Methotrexate.
    González-Mercado MG; Rivas F; Gallegos-Arreola MP; Morán-Moguel MC; Salazar-Páramo M; González-López L; Gámez-Nava JI; Muñoz-Valle JF; Medina-Coss Y León R; González-Mercado A; Aceves MA; Dávalos NO; Macías-Chumacera A; Dávalos IP
    Genet Test Mol Biomarkers; 2017 Nov; 21(11):698-704. PubMed ID: 28994615
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Associations between single-nucleotide polymorphisms of RFC-1, GGH, MTHFR , TYMS, and TCII genes and the efficacy and toxicity of methotrexate treatment in patients with rheumatoid arthritis.
    Świerkot J; Ślęzak R; Karpiński P; Pawłowska J; Noga L; Szechiński J; Wiland P
    Pol Arch Med Wewn; 2015; 125(3):152-61. PubMed ID: 25599563
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?
    Ghodke Y; Chopra A; Joshi K; Patwardhan B
    Clin Rheumatol; 2008 Jun; 27(6):787-9. PubMed ID: 18274813
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Methylene tetrahydrofolate reductase genotypes frequencies: association with toxicity and response to methotrexate in rheumatoid arthritis patients.
    Saleh MM; Irshaid YM; Mustafa KN
    Int J Clin Pharmacol Ther; 2015 Feb; 53(2):154-62. PubMed ID: 25492850
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.
    Wessels JA; de Vries-Bouwstra JK; Heijmans BT; Slagboom PE; Goekoop-Ruiterman YP; Allaart CF; Kerstens PJ; van Zeben D; Breedveld FC; Dijkmans BA; Huizinga TW; Guchelaar HJ
    Arthritis Rheum; 2006 Apr; 54(4):1087-95. PubMed ID: 16572443
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Correlation between methotrexate efficacy & toxicity with C677T polymorphism of the methylenetetrahydrofolate gene in rheumatoid arthritis patients on folate supplementation.
    Aggarwal P; Naik S; Mishra KP; Aggarwal A; Misra R
    Indian J Med Res; 2006 Nov; 124(5):521-6. PubMed ID: 17213520
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The impact of C677T and A1298C MTHFR polymorphisms on methotrexate therapeutic response in East Bohemian region rheumatoid arthritis patients.
    Soukup T; Dosedel M; Pavek P; Nekvindova J; Barvik I; Bubancova I; Bradna P; Kubena AA; Carazo AF; Veleta T; Vlcek J
    Rheumatol Int; 2015 Jul; 35(7):1149-61. PubMed ID: 25618758
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Association of MTHFR C677T, MTHFR A1298C, and MTRR A66G Polymorphisms with Neural Tube Defects in Tunisian Parents.
    Nasri K; Midani F; Kallel A; Ben Jemaa N; Aloui M; Boulares M; Lassoued M; Ben Halima M; Ben Wafi S; Soussi M; Mahjoubi I; Baara A; Ben Fradj MK; Omar S; Feki M; Jemaa R; Gaigi SS; Marrakchi R
    Pathobiology; 2019; 86(4):190-200. PubMed ID: 31238314
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Association Between MTHFR C677T Polymorphism and Methotrexate Treatment Outcome in Rheumatoid Arthritis Patients: A Systematic Review and Meta-Analysis.
    Shao W; Yuan Y; Li Y
    Genet Test Mol Biomarkers; 2017 May; 21(5):275-285. PubMed ID: 28277784
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.
    Ranganathan P; Culverhouse R; Marsh S; Mody A; Scott-Horton TJ; Brasington R; Joseph A; Reddy V; Eisen S; McLeod HL
    J Rheumatol; 2008 Apr; 35(4):572-9. PubMed ID: 18381794
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Associations between the C677T and A1298C polymorphisms of MTHFR and the efficacy and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis.
    Lee YH; Song GG
    Clin Drug Investig; 2010; 30(2):101-8. PubMed ID: 20067328
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene.
    Berkun Y; Levartovsky D; Rubinow A; Orbach H; Aamar S; Grenader T; Abou Atta I; Mevorach D; Friedman G; Ben-Yehuda A
    Ann Rheum Dis; 2004 Oct; 63(10):1227-31. PubMed ID: 15361376
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.