BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

479 related articles for article (PubMed ID: 26077851)

  • 1. Yeast model analysis of novel polymerase gamma variants found in patients with autosomal recessive mitochondrial disease.
    Kaliszewska M; Kruszewski J; Kierdaszuk B; Kostera-Pruszczyk A; Nojszewska M; Łusakowska A; Vizueta J; Sabat D; Lutyk D; Lower M; Piekutowska-Abramczuk D; Kaniak-Golik A; Pronicka E; Kamińska A; Bartnik E; Golik P; Tońska K
    Hum Genet; 2015 Sep; 134(9):951-66. PubMed ID: 26077851
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mip1 containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mtDNA in Saccharomyces cerevisiae.
    Stumpf JD; Bailey CM; Spell D; Stillwagon M; Anderson KS; Copeland WC
    Hum Mol Genet; 2010 Jun; 19(11):2123-33. PubMed ID: 20185557
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mitochondrial DNA defects in Saccharomyces cerevisiae caused by functional interactions between DNA polymerase gamma mutations associated with disease in human.
    Baruffini E; Ferrero I; Foury F
    Biochim Biophys Acta; 2007 Dec; 1772(11-12):1225-35. PubMed ID: 17980715
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combined use of Saccharomyces cerevisiae, Caenorhabditis elegans and patient fibroblasts leads to the identification of clofilium tosylate as a potential therapeutic chemical against POLG-related diseases.
    Pitayu L; Baruffini E; Rodier C; Rötig A; Lodi T; Delahodde A
    Hum Mol Genet; 2016 Feb; 25(4):715-27. PubMed ID: 26692522
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia.
    Stuart GR; Santos JH; Strand MK; Van Houten B; Copeland WC
    Hum Mol Genet; 2006 Jan; 15(2):363-74. PubMed ID: 16368709
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A cluster of pathogenic mutations in the 3'-5' exonuclease domain of DNA polymerase gamma defines a novel module coupling DNA synthesis and degradation.
    Szczepanowska K; Foury F
    Hum Mol Genet; 2010 Sep; 19(18):3516-29. PubMed ID: 20601675
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution to the knowledge about human POLG-related disorders.
    Gilea AI; Magistrati M; Notaroberto I; Tiso N; Dallabona C; Baruffini E
    IUBMB Life; 2023 Dec; 75(12):983-1002. PubMed ID: 37470284
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Predicting the contribution of novel POLG mutations to human disease through analysis in yeast model.
    Baruffini E; Horvath R; Dallabona C; Czermin B; Lamantea E; Bindoff L; Invernizzi F; Ferrero I; Zeviani M; Lodi T
    Mitochondrion; 2011 Jan; 11(1):182-90. PubMed ID: 20883824
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antimutator alleles of yeast DNA polymerase gamma modulate the balance between DNA synthesis and excision.
    Foury F; Szczepanowska K
    PLoS One; 2011; 6(11):e27847. PubMed ID: 22114710
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MMS exposure promotes increased MtDNA mutagenesis in the presence of replication-defective disease-associated DNA polymerase γ variants.
    Stumpf JD; Copeland WC
    PLoS Genet; 2014 Oct; 10(10):e1004748. PubMed ID: 25340760
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetic and chemical rescue of the Saccharomyces cerevisiae phenotype induced by mitochondrial DNA polymerase mutations associated with progressive external ophthalmoplegia in humans.
    Baruffini E; Lodi T; Dallabona C; Puglisi A; Zeviani M; Ferrero I
    Hum Mol Genet; 2006 Oct; 15(19):2846-55. PubMed ID: 16940310
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Yeast mitochondrial DNA polymerase is a highly processive single-subunit enzyme.
    Viikov K; Väljamäe P; Sedman J
    Mitochondrion; 2011 Jan; 11(1):119-26. PubMed ID: 20807588
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The carboxyl-terminal extension on fungal mitochondrial DNA polymerases: identification of a critical region of the enzyme from Saccharomyces cerevisiae.
    Young MJ; Theriault SS; Li M; Court DA
    Yeast; 2006 Jan; 23(2):101-16. PubMed ID: 16491467
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The unfolding clinical spectrum of POLG mutations.
    Blok MJ; van den Bosch BJ; Jongen E; Hendrickx A; de Die-Smulders CE; Hoogendijk JE; Brusse E; de Visser M; Poll-The BT; Bierau J; de Coo IF; Smeets HJ
    J Med Genet; 2009 Nov; 46(11):776-85. PubMed ID: 19578034
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Co-occurrence of four nucleotide changes associated with an adult mitochondrial ataxia phenotype.
    Zabalza R; Nurminen A; Kaguni LS; Garesse R; Gallardo ME; Bornstein B
    BMC Res Notes; 2014 Dec; 7():883. PubMed ID: 25488682
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Yeast cells expressing the human mitochondrial DNA polymerase reveal correlations between polymerase fidelity and human disease progression.
    Qian Y; Kachroo AH; Yellman CM; Marcotte EM; Johnson KA
    J Biol Chem; 2014 Feb; 289(9):5970-85. PubMed ID: 24398692
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence for a two membrane-spanning autonomous mitochondrial DNA replisome.
    Meeusen S; Nunnari J
    J Cell Biol; 2003 Nov; 163(3):503-10. PubMed ID: 14597773
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A non-radioactive DNA synthesis assay demonstrates that elements of the Sigma 1278b Mip1 mitochondrial DNA polymerase domain and C-terminal extension facilitate robust enzyme activity.
    Young MJ; Imperial RJ; Lakhi S; Court DA
    Yeast; 2021 Apr; 38(4):262-275. PubMed ID: 33270277
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synergistic Effects of the
    DeBalsi KL; Longley MJ; Hoff KE; Copeland WC
    J Biol Chem; 2017 Mar; 292(10):4198-4209. PubMed ID: 28154168
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The exonuclease activity of the yeast mitochondrial DNA polymerase γ suppresses mitochondrial DNA deletions between short direct repeats in Saccharomyces cerevisiae.
    Stumpf JD; Copeland WC
    Genetics; 2013 Jun; 194(2):519-22. PubMed ID: 23589460
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.