BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1391 related articles for article (PubMed ID: 26080426)

  • 1. Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP.
    Corbett GT; Gonzalez FJ; Pahan K
    Proc Natl Acad Sci U S A; 2015 Jul; 112(27):8445-50. PubMed ID: 26080426
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model.
    Luo R; Su LY; Li G; Yang J; Liu Q; Yang LX; Zhang DF; Zhou H; Xu M; Fan Y; Li J; Yao YG
    Autophagy; 2020 Jan; 16(1):52-69. PubMed ID: 30898012
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin.
    Tippmann F; Hundt J; Schneider A; Endres K; Fahrenholz F
    FASEB J; 2009 Jun; 23(6):1643-54. PubMed ID: 19144697
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unfolded protein response signaling by transcription factor XBP-1 regulates ADAM10 and is affected in Alzheimer's disease.
    Reinhardt S; Schuck F; Grösgen S; Riemenschneider M; Hartmann T; Postina R; Grimm M; Endres K
    FASEB J; 2014 Feb; 28(2):978-97. PubMed ID: 24165480
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of neuron-specific ADAM10 modulation in an in vivo model of acute excitotoxic stress.
    Clement AB; Hanstein R; Schröder A; Nagel H; Endres K; Fahrenholz F; Behl C
    Neuroscience; 2008 Mar; 152(2):459-68. PubMed ID: 18276079
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.
    Peng Y; Lee DY; Jiang L; Ma Z; Schachter SC; Lemere CA
    Neuroscience; 2007 Dec; 150(2):386-95. PubMed ID: 17945434
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Treadmill workout activates PPARα in the hippocampus to upregulate ADAM10, decrease plaques and improve cognitive functions in 5XFAD mouse model of Alzheimer's disease.
    Rangasamy SB; Jana M; Dasarathi S; Kundu M; Pahan K
    Brain Behav Immun; 2023 Mar; 109():204-218. PubMed ID: 36682514
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.
    Panmanee J; Nopparat C; Chavanich N; Shukla M; Mukda S; Song W; Vincent B; Govitrapong P
    J Pineal Res; 2015 Oct; 59(3):308-20. PubMed ID: 26123100
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of Folic Acid on Secretases Involved in Aβ Deposition in APP/PS1 Mice.
    Tian T; Bai D; Li W; Huang GW; Liu H
    Nutrients; 2016 Sep; 8(9):. PubMed ID: 27618097
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of a dominant-negative form of ADAM10 in a mouse model of Alzheimer's disease.
    Schroeder A; Fahrenholz F; Schmitt U
    J Alzheimers Dis; 2009; 16(2):309-14. PubMed ID: 19221420
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to Synaptic Deficits in Fragile X Syndrome.
    Pasciuto E; Ahmed T; Wahle T; Gardoni F; D'Andrea L; Pacini L; Jacquemont S; Tassone F; Balschun D; Dotti CG; Callaerts-Vegh Z; D'Hooge R; Müller UC; Di Luca M; De Strooper B; Bagni C
    Neuron; 2015 Jul; 87(2):382-98. PubMed ID: 26182420
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cryptotanshinione upregulates alpha-secretase by activation PI3K pathway in cortical neurons.
    Mei Z; Situ B; Tan X; Zheng S; Zhang F; Yan P; Liu P
    Brain Res; 2010 Aug; 1348():165-73. PubMed ID: 20595051
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein.
    Harris B; Pereira I; Parkin E
    Brain Res; 2009 Nov; 1296():203-15. PubMed ID: 19679113
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
    Shackleton B; Crawford F; Bachmeier C
    Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines.
    Colombo A; Wang H; Kuhn PH; Page R; Kremmer E; Dempsey PJ; Crawford HC; Lichtenthaler SF
    Neurobiol Dis; 2013 Jan; 49():137-47. PubMed ID: 22940630
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Octyl gallate markedly promotes anti-amyloidogenic processing of APP through estrogen receptor-mediated ADAM10 activation.
    Zhang SQ; Sawmiller D; Li S; Rezai-Zadeh K; Hou H; Zhou S; Shytle D; Giunta B; Fernandez F; Mori T; Tan J
    PLoS One; 2013; 8(8):e71913. PubMed ID: 23977176
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alpha-secretase cleavage of the amyloid precursor protein: proteolysis regulated by signaling pathways and protein trafficking.
    Lichtenthaler SF
    Curr Alzheimer Res; 2012 Feb; 9(2):165-77. PubMed ID: 21605033
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.
    Meng P; Yoshida H; Matsumiya T; Imaizumi T; Tanji K; Xing F; Hayakari R; Dempoya J; Tatsuta T; Aizawa-Yashiro T; Mimura J; Kosaka K; Itoh K; Satoh K
    Neurosci Res; 2013 Feb; 75(2):94-102. PubMed ID: 23257508
    [TBL] [Abstract][Full Text] [Related]  

  • 19. η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
    Willem M; Tahirovic S; Busche MA; Ovsepian SV; Chafai M; Kootar S; Hornburg D; Evans LD; Moore S; Daria A; Hampel H; Müller V; Giudici C; Nuscher B; Wenninger-Weinzierl A; Kremmer E; Heneka MT; Thal DR; Giedraitis V; Lannfelt L; Müller U; Livesey FJ; Meissner F; Herms J; Konnerth A; Marie H; Haass C
    Nature; 2015 Oct; 526(7573):443-7. PubMed ID: 26322584
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Auraptene increases the production of amyloid-β via c-Jun N-terminal kinase-dependent activation of γ-secretase.
    Jung CG; Uhm KO; Horike H; Kim MJ; Misumi S; Ishida A; Ueda Y; Choi EK; Kim YS; Michikawa M; Hida H
    J Alzheimers Dis; 2015; 43(4):1215-28. PubMed ID: 25147119
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 70.