181 related articles for article (PubMed ID: 26081291)
21. Unexpected small molecules as novel SIRT2 suicide inhibitors.
Chen X; Zou Y; Wang J; Cao Z; Liu J; Li Y; Zhao Y; He B
Bioorg Med Chem; 2020 Mar; 28(6):115353. PubMed ID: 32061485
[TBL] [Abstract][Full Text] [Related]
22. A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation.
Galleano I; Schiedel M; Jung M; Madsen AS; Olsen CA
J Med Chem; 2016 Feb; 59(3):1021-31. PubMed ID: 26788965
[TBL] [Abstract][Full Text] [Related]
23. Human sirtuins are differentially sensitive to inhibition by nitrosating agents and other cysteine oxidants.
Kalous KS; Wynia-Smith SL; Summers SB; Smith BC
J Biol Chem; 2020 Jun; 295(25):8524-8536. PubMed ID: 32371394
[TBL] [Abstract][Full Text] [Related]
24. N(epsilon)-thioacetyl-lysine-containing tri-, tetra-, and pentapeptides as SIRT1 and SIRT2 inhibitors.
Kiviranta PH; Suuronen T; Wallén EA; Leppänen J; Tervonen J; Kyrylenko S; Salminen A; Poso A; Jarho EM
J Med Chem; 2009 Apr; 52(7):2153-6. PubMed ID: 19296597
[TBL] [Abstract][Full Text] [Related]
25. Discovery of bicyclic pyrazoles as class III histone deacetylase SIRT1 and SIRT2 inhibitors.
Therrien E; Larouche G; Nguyen N; Rahil J; Lemieux AM; Li Z; Fournel M; Yan TP; Landry AJ; Lefebvre S; Wang JJ; MacBeth K; Heise C; Nguyen A; Besterman JM; Déziel R; Wahhab A
Bioorg Med Chem Lett; 2015 Jun; 25(12):2514-8. PubMed ID: 25971769
[TBL] [Abstract][Full Text] [Related]
26. A scaffold replacement approach towards new sirtuin 2 inhibitors.
Seifert T; Malo M; Kokkola T; Stéen EJL; Meinander K; Wallén EAA; Jarho EM; Luthman K
Bioorg Med Chem; 2020 Jan; 28(2):115231. PubMed ID: 31848116
[TBL] [Abstract][Full Text] [Related]
27. Structure-based design of pseudopeptidic inhibitors for SIRT1 and SIRT2.
Huhtiniemi T; Salo HS; Suuronen T; Poso A; Salminen A; Leppänen J; Jarho E; Lahtela-Kakkonen M
J Med Chem; 2011 Oct; 54(19):6456-68. PubMed ID: 21895016
[TBL] [Abstract][Full Text] [Related]
28. Pharmacological Advantage of SIRT2-Selective versus pan-SIRT1-3 Inhibitors.
Hong JY; Fernandez I; Anmangandla A; Lu X; Bai JJ; Lin H
ACS Chem Biol; 2021 Jul; 16(7):1266-1275. PubMed ID: 34139124
[TBL] [Abstract][Full Text] [Related]
29. Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3.
Disch JS; Evindar G; Chiu CH; Blum CA; Dai H; Jin L; Schuman E; Lind KE; Belyanskaya SL; Deng J; Coppo F; Aquilani L; Graybill TL; Cuozzo JW; Lavu S; Mao C; Vlasuk GP; Perni RB
J Med Chem; 2013 May; 56(9):3666-79. PubMed ID: 23570514
[TBL] [Abstract][Full Text] [Related]
30. Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins.
Feldman JL; Baeza J; Denu JM
J Biol Chem; 2013 Oct; 288(43):31350-6. PubMed ID: 24052263
[TBL] [Abstract][Full Text] [Related]
31. Javamide-I-O-methyl ester increases p53 acetylation and induces cell death via activating caspase 3/7 in monocytic THP-1 cells.
Park JB
Phytomedicine; 2016 Dec; 23(13):1647-1652. PubMed ID: 27823629
[TBL] [Abstract][Full Text] [Related]
32. Discovery and validation of SIRT2 inhibitors based on tenovin-6: use of a ¹H-NMR method to assess deacetylase activity.
Pirrie L; McCarthy AR; Major LL; Morkūnaitė V; Zubrienė A; Matulis D; Lain S; Lebl T; Westwood NJ
Molecules; 2012 Oct; 17(10):12206-24. PubMed ID: 23079492
[TBL] [Abstract][Full Text] [Related]
33. Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile.
Rotili D; Carafa V; Tarantino D; Botta G; Nebbioso A; Altucci L; Mai A
Bioorg Med Chem; 2011 Jun; 19(12):3659-68. PubMed ID: 21306905
[TBL] [Abstract][Full Text] [Related]
34. The mimics of N
Wang C; Wang F; Chen X; Zou Y; Zhu H; Zhao Q; Shen J; Li Y; Li Y; He B
Bioorg Med Chem Lett; 2018 Aug; 28(14):2375-2378. PubMed ID: 29921476
[TBL] [Abstract][Full Text] [Related]
35. Identification of a sirtuin 3 inhibitor that displays selectivity over sirtuin 1 and 2.
Galli U; Mesenzani O; Coppo C; Sorba G; Canonico PL; Tron GC; Genazzani AA
Eur J Med Chem; 2012 Sep; 55():58-66. PubMed ID: 22835719
[TBL] [Abstract][Full Text] [Related]
36. Finding Potent Sirt Inhibitor in Coffee: Isolation, Confirmation and Synthesis of Javamide-II (N-Caffeoyltryptophan) as Sirt1/2 Inhibitor.
Park JB
PLoS One; 2016; 11(3):e0150392. PubMed ID: 26986569
[TBL] [Abstract][Full Text] [Related]
37. New ε-N-thioglutaryl-lysine derivatives as SIRT5 inhibitors: Chemical synthesis, kinetic and crystallographic studies.
Deng J; Liu ZM; Zhu KR; Cui GL; Liu LX; Yan YH; Ning XL; Yu ZJ; Li GB; Qi QR
Bioorg Chem; 2023 Jun; 135():106487. PubMed ID: 36996510
[TBL] [Abstract][Full Text] [Related]
38. 1,2,3-Triazole-Dithiocarbamate Hybrids, a Group of Novel Cell Active SIRT1 Inhibitors.
Zheng YC; Wang LZ; Zhao LJ; Zhao LJ; Zhan QN; Ma JL; Zhang B; Wang MM; Wang ZR; Li JF; Liu Y; Chen ZS; Shen DD; Liu XQ; Ren M; Lv WL; Zhao W; Duan YC; Liu HM
Cell Physiol Biochem; 2016; 38(1):185-93. PubMed ID: 26784898
[TBL] [Abstract][Full Text] [Related]
39. Synthesis and evaluation of novel benzimidazole derivatives as sirtuin inhibitors with antitumor activities.
Yoon YK; Ali MA; Wei AC; Choon TS; Osman H; Parang K; Shirazi AN
Bioorg Med Chem; 2014 Jan; 22(2):703-10. PubMed ID: 24387981
[TBL] [Abstract][Full Text] [Related]
40. Current advances in the synthesis and antitumoral activity of SIRT1-2 inhibitors by modulation of p53 and pro-apoptotic proteins.
Botta G; De Santis LP; Saladino R
Curr Med Chem; 2012; 19(34):5871-84. PubMed ID: 22998567
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]