203 related articles for article (PubMed ID: 26083237)
21. Crystalline form of a neutrophil elastase inhibitor, 6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-N-{[5-(methylsulfonyl)pyridin-2-yl]methyl}-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide p-toluene sulfonate - is it AZD-9668?: WO-2010094964.
Norman P
Expert Opin Ther Pat; 2011 Feb; 21(2):277-80. PubMed ID: 21222548
[TBL] [Abstract][Full Text] [Related]
22. Neutrophil elastase inhibitors: recent advances in the development of mechanism-based and nonelectrophilic inhibitors.
Sjö P
Future Med Chem; 2012 Apr; 4(5):651-60. PubMed ID: 22458683
[TBL] [Abstract][Full Text] [Related]
23. Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor.
Hansen G; Gielen-Haertwig H; Reinemer P; Schomburg D; Harrenga A; Niefind K
J Mol Biol; 2011 Jun; 409(5):681-91. PubMed ID: 21549129
[TBL] [Abstract][Full Text] [Related]
24. Natural compounds as inhibitors of human neutrophil elastase.
Siedle B; Hrenn A; Merfort I
Planta Med; 2007 May; 73(5):401-20. PubMed ID: 17447201
[TBL] [Abstract][Full Text] [Related]
25. Tailoring elastase inhibition with synthetic peptides.
Vasconcelos A; Azoia NG; Carvalho AC; Gomes AC; Güebitz G; Cavaco-Paulo A
Eur J Pharmacol; 2011 Sep; 666(1-3):53-60. PubMed ID: 21658384
[TBL] [Abstract][Full Text] [Related]
26. 1,5,6,7-Tetrahydro-4H-indazol-4-ones as human neutrophil elastase (HNE) inhibitors.
Cantini N; Crocetti L; Guerrini G; Vergelli C; Schepetkin IA; Pallecchi M; Bartolucci G; Quinn MT; Teodori E; Giovannoni MP
Bioorg Med Chem Lett; 2021 Nov; 52():128380. PubMed ID: 34563669
[TBL] [Abstract][Full Text] [Related]
27. Sirtinol inhibits neutrophil elastase activity and attenuates lipopolysaccharide-mediated acute lung injury in mice.
Tsai YF; Yu HP; Chang WY; Liu FC; Huang ZC; Hwang TL
Sci Rep; 2015 Feb; 5():8347. PubMed ID: 25666548
[TBL] [Abstract][Full Text] [Related]
28. Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7.
Chen QY; Luo D; Seabra GM; Luesch H
Bioorg Med Chem; 2020 Dec; 28(23):115756. PubMed ID: 33002682
[TBL] [Abstract][Full Text] [Related]
29. Human neutrophil elastase inhibitory potential of flavonoids from Campylotropis hirtella and their kinetics.
Tan XF; Kim DW; Song YH; Kim JY; Yuk HJ; Wang Y; Curtis-Long MJ; Park KH
J Enzyme Inhib Med Chem; 2016; 31(sup1):16-22. PubMed ID: 27558014
[TBL] [Abstract][Full Text] [Related]
30. Discrimination of Methionine Sulfoxide and Sulfone by Human Neutrophil Elastase.
Leahy D; Grant C; Jackson A; Duff A; Tardiota N; Van Haeften J; Chen X; Peake JM; Kruppa MD; Smith ET; Johnson DA; Lott WB; Harris JM
Molecules; 2021 Sep; 26(17):. PubMed ID: 34500777
[TBL] [Abstract][Full Text] [Related]
31. Pharmacology of N-[4-(4-morpholinylcarbonyl)benzoyl]-L-valyl-N- [3,3,4,4,4-pentafluoro-1-(1-methylethyl)-2-oxobutyl]-L-prolinamide (MDL 101,146): a potent orally active inhibitor of human neutrophil elastase.
Durham SL; Hare CM; Angelastro MR; Burkhart JP; Koehl JR; Marquart AL; Mehdi S; Peet NP; Janusz MJ
J Pharmacol Exp Ther; 1994 Jul; 270(1):185-91. PubMed ID: 8035315
[TBL] [Abstract][Full Text] [Related]
32. Exploration of nitrogen heterocycle scaffolds for the development of potent human neutrophil elastase inhibitors.
Cantini N; Khlebnikov AI; Crocetti L; Schepetkin IA; Floresta G; Guerrini G; Vergelli C; Bartolucci G; Quinn MT; Giovannoni MP
Bioorg Med Chem; 2021 Jan; 29():115836. PubMed ID: 33218895
[TBL] [Abstract][Full Text] [Related]
33. Two acetylated megastigmane glycosides from the leaves of Ilex paraguariensis.
Xu GH; Kim YH; Choo SJ; Ryoo IJ; Yoo JK; Ahn JS; Yoo ID
Arch Pharm Res; 2010 Mar; 33(3):369-73. PubMed ID: 20361300
[TBL] [Abstract][Full Text] [Related]
34. Synthesis and pharmacological characterization of 2-aminobenzaldehyde oxime analogs as dual inhibitors of neutrophil elastase and proteinase 3.
Hwang TL; Wang WH; Wang TY; Yu HP; Hsieh PW
Bioorg Med Chem; 2015 Mar; 23(5):1123-34. PubMed ID: 25650311
[TBL] [Abstract][Full Text] [Related]
35. Identification and characterization of aptameric inhibitors of human neutrophil elastase.
Malicki S; Książek M; Sochaj Gregorczyk A; Kamińska M; Golda A; Chruścicka B; Mizgalska D; Potempa J; Marti HP; Kozieł J; Wieczorek M; Pieczykolan J; Mydel P; Dubin G
J Biol Chem; 2023 Aug; 299(8):104889. PubMed ID: 37286041
[TBL] [Abstract][Full Text] [Related]
36. Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase.
Crocetti L; Schepetkin IA; Cilibrizzi A; Graziano A; Vergelli C; Giomi D; Khlebnikov AI; Quinn MT; Giovannoni MP
J Med Chem; 2013 Aug; 56(15):6259-72. PubMed ID: 23844670
[TBL] [Abstract][Full Text] [Related]
37. Design and synthesis of sirtinol analogs as human neutrophil elastase inhibitors.
Hwang TL; Lin JY; Kuo LM; Kumar Dhandabani G; Hsieh PW
Bioorg Med Chem Lett; 2024 Jan; 97():129544. PubMed ID: 37939864
[TBL] [Abstract][Full Text] [Related]
38. SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase.
Zheng Q; Woehl JL; Kitamura S; Santos-Martins D; Smedley CJ; Li G; Forli S; Moses JE; Wolan DW; Sharpless KB
Proc Natl Acad Sci U S A; 2019 Sep; 116(38):18808-18814. PubMed ID: 31484779
[TBL] [Abstract][Full Text] [Related]
39. A selective reversible azapeptide inhibitor of human neutrophil proteinase 3 derived from a high affinity FRET substrate.
Epinette C; Croix C; Jaquillard L; Marchand-Adam S; Kellenberger C; Lalmanach G; Cadene M; Viaud-Massuard MC; Gauthier F; Korkmaz B
Biochem Pharmacol; 2012 Mar; 83(6):788-96. PubMed ID: 22209715
[TBL] [Abstract][Full Text] [Related]
40. Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors.
Dau T; Sarker RS; Yildirim AO; Eickelberg O; Jenne DE
Nat Commun; 2015 Apr; 6():6722. PubMed ID: 25857284
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
