326 related articles for article (PubMed ID: 26085088)
1. The DNA Methyltransferase DNMT1 and Tyrosine-Protein Kinase KIT Cooperatively Promote Resistance to 5-Aza-2'-deoxycytidine (Decitabine) and Midostaurin (PKC412) in Lung Cancer Cells.
Yan F; Shen N; Pang J; Molina JR; Yang P; Liu S
J Biol Chem; 2015 Jul; 290(30):18480-94. PubMed ID: 26085088
[TBL] [Abstract][Full Text] [Related]
2. 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal.
Ghoshal K; Datta J; Majumder S; Bai S; Kutay H; Motiwala T; Jacob ST
Mol Cell Biol; 2005 Jun; 25(11):4727-41. PubMed ID: 15899874
[TBL] [Abstract][Full Text] [Related]
3. Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo.
Alcazar O; Achberger S; Aldrich W; Hu Z; Negrotto S; Saunthararajah Y; Triozzi P
Int J Cancer; 2012 Jul; 131(1):18-29. PubMed ID: 21796622
[TBL] [Abstract][Full Text] [Related]
4. Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.
Liu WB; Cui ZH; Ao L; Zhou ZY; Zhou YH; Yuan XY; Xiang YL; Liu JY; Cao J
Toxicol Appl Pharmacol; 2011 Feb; 251(1):70-8. PubMed ID: 21163286
[TBL] [Abstract][Full Text] [Related]
5. Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2'-deoxycytidine in human leukemic KG1 cells.
Vispé S; Deroide A; Davoine E; Desjobert C; Lestienne F; Fournier L; Novosad N; Bréand S; Besse J; Busato F; Tost J; De Vries L; Cussac D; Riond J; Arimondo PB
Oncotarget; 2015 Jun; 6(17):15265-82. PubMed ID: 25948775
[TBL] [Abstract][Full Text] [Related]
6. Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent.
Lin HY; Kuo YC; Weng YI; Lai IL; Huang TH; Lin SP; Niu DM; Chen CS
Prostate; 2012 Dec; 72(16):1767-78. PubMed ID: 22539223
[TBL] [Abstract][Full Text] [Related]
7. Pancreatic cancer DNMT1 expression and sensitivity to DNMT1 inhibitors.
Li A; Omura N; Hong SM; Goggins M
Cancer Biol Ther; 2010 Feb; 9(4):321-9. PubMed ID: 20234167
[TBL] [Abstract][Full Text] [Related]
8. Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells.
Kastl L; Brown I; Schofield AC
Int J Oncol; 2010 May; 36(5):1235-41. PubMed ID: 20372798
[TBL] [Abstract][Full Text] [Related]
9. DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.
Palii SS; Van Emburgh BO; Sankpal UT; Brown KD; Robertson KD
Mol Cell Biol; 2008 Jan; 28(2):752-71. PubMed ID: 17991895
[TBL] [Abstract][Full Text] [Related]
10. Combinations of DNA methyltransferase and histone deacetylase inhibitors induce DNA damage in small cell lung cancer cells: correlation of resistance with IFN-stimulated gene expression.
Luszczek W; Cheriyath V; Mekhail TM; Borden EC
Mol Cancer Ther; 2010 Aug; 9(8):2309-21. PubMed ID: 20682643
[TBL] [Abstract][Full Text] [Related]
11. Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4'-thio-2'-deoxycytidine and 5-aza-4'-thio-2'-deoxycytidine.
Thottassery JV; Sambandam V; Allan PW; Maddry JA; Maxuitenko YY; Tiwari K; Hollingshead M; Parker WB
Cancer Chemother Pharmacol; 2014 Aug; 74(2):291-302. PubMed ID: 24908436
[TBL] [Abstract][Full Text] [Related]
12. DNA methylation and not H3K4 trimethylation dictates the expression status of miR-152 gene which inhibits migration of breast cancer cells via DNMT1/CDH1 loop.
Sengupta D; Deb M; Rath SK; Kar S; Parbin S; Pradhan N; Patra SK
Exp Cell Res; 2016 Aug; 346(2):176-87. PubMed ID: 27475839
[TBL] [Abstract][Full Text] [Related]
13. A regulatory circuit composed of DNA methyltransferases and receptor tyrosine kinases controls lung cancer cell aggressiveness.
Yan F; Shen N; Pang J; Zhao N; Deng B; Li B; Yang Y; Yang P; Molina JR; Liu S
Oncogene; 2017 Dec; 36(50):6919-6928. PubMed ID: 28869603
[TBL] [Abstract][Full Text] [Related]
14. Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor.
Gray SG; Baird AM; O'Kelly F; Nikolaidis G; Almgren M; Meunier A; Dockry E; Hollywood D; Ekström TJ; Perry AS; O'Byrne KJ
Int J Mol Med; 2012 Dec; 30(6):1505-11. PubMed ID: 23007409
[TBL] [Abstract][Full Text] [Related]
15. Promoter methylation status of tumor suppressor genes and inhibition of expression of DNA methyltransferase 1 in non-small cell lung cancer.
Liu B; Song J; Luan J; Sun X; Bai J; Wang H; Li A; Zhang L; Feng X; Du Z
Exp Biol Med (Maywood); 2016 Aug; 241(14):1531-9. PubMed ID: 27190263
[TBL] [Abstract][Full Text] [Related]
16. 5-aza-2'-deoxycytidine induces alterations in murine spermatogenesis and pregnancy outcome.
Kelly TL; Li E; Trasler JM
J Androl; 2003; 24(6):822-30. PubMed ID: 14581508
[TBL] [Abstract][Full Text] [Related]
17. Azacytidine and decitabine induce gene-specific and non-random DNA demethylation in human cancer cell lines.
Hagemann S; Heil O; Lyko F; Brueckner B
PLoS One; 2011 Mar; 6(3):e17388. PubMed ID: 21408221
[TBL] [Abstract][Full Text] [Related]
18. RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells.
Suzuki M; Sunaga N; Shames DS; Toyooka S; Gazdar AF; Minna JD
Cancer Res; 2004 May; 64(9):3137-43. PubMed ID: 15126351
[TBL] [Abstract][Full Text] [Related]
19. Efficacy of decitabine-loaded nanogels in overcoming cancer drug resistance is mediated via sustained DNA methyltransferase 1 (DNMT1) depletion.
Vijayaraghavalu S; Labhasetwar V
Cancer Lett; 2013 Apr; 331(1):122-9. PubMed ID: 23305699
[TBL] [Abstract][Full Text] [Related]
20. 5-aza-2'-deoxycytidine-induced genome rearrangements are mediated by DNMT1.
Maslov AY; Lee M; Gundry M; Gravina S; Strogonova N; Tazearslan C; Bendebury A; Suh Y; Vijg J
Oncogene; 2012 Dec; 31(50):5172-9. PubMed ID: 22349820
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]