BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

326 related articles for article (PubMed ID: 26085088)

  • 1. The DNA Methyltransferase DNMT1 and Tyrosine-Protein Kinase KIT Cooperatively Promote Resistance to 5-Aza-2'-deoxycytidine (Decitabine) and Midostaurin (PKC412) in Lung Cancer Cells.
    Yan F; Shen N; Pang J; Molina JR; Yang P; Liu S
    J Biol Chem; 2015 Jul; 290(30):18480-94. PubMed ID: 26085088
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal.
    Ghoshal K; Datta J; Majumder S; Bai S; Kutay H; Motiwala T; Jacob ST
    Mol Cell Biol; 2005 Jun; 25(11):4727-41. PubMed ID: 15899874
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo.
    Alcazar O; Achberger S; Aldrich W; Hu Z; Negrotto S; Saunthararajah Y; Triozzi P
    Int J Cancer; 2012 Jul; 131(1):18-29. PubMed ID: 21796622
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.
    Liu WB; Cui ZH; Ao L; Zhou ZY; Zhou YH; Yuan XY; Xiang YL; Liu JY; Cao J
    Toxicol Appl Pharmacol; 2011 Feb; 251(1):70-8. PubMed ID: 21163286
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2'-deoxycytidine in human leukemic KG1 cells.
    Vispé S; Deroide A; Davoine E; Desjobert C; Lestienne F; Fournier L; Novosad N; Bréand S; Besse J; Busato F; Tost J; De Vries L; Cussac D; Riond J; Arimondo PB
    Oncotarget; 2015 Jun; 6(17):15265-82. PubMed ID: 25948775
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent.
    Lin HY; Kuo YC; Weng YI; Lai IL; Huang TH; Lin SP; Niu DM; Chen CS
    Prostate; 2012 Dec; 72(16):1767-78. PubMed ID: 22539223
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pancreatic cancer DNMT1 expression and sensitivity to DNMT1 inhibitors.
    Li A; Omura N; Hong SM; Goggins M
    Cancer Biol Ther; 2010 Feb; 9(4):321-9. PubMed ID: 20234167
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells.
    Kastl L; Brown I; Schofield AC
    Int J Oncol; 2010 May; 36(5):1235-41. PubMed ID: 20372798
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.
    Palii SS; Van Emburgh BO; Sankpal UT; Brown KD; Robertson KD
    Mol Cell Biol; 2008 Jan; 28(2):752-71. PubMed ID: 17991895
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combinations of DNA methyltransferase and histone deacetylase inhibitors induce DNA damage in small cell lung cancer cells: correlation of resistance with IFN-stimulated gene expression.
    Luszczek W; Cheriyath V; Mekhail TM; Borden EC
    Mol Cancer Ther; 2010 Aug; 9(8):2309-21. PubMed ID: 20682643
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4'-thio-2'-deoxycytidine and 5-aza-4'-thio-2'-deoxycytidine.
    Thottassery JV; Sambandam V; Allan PW; Maddry JA; Maxuitenko YY; Tiwari K; Hollingshead M; Parker WB
    Cancer Chemother Pharmacol; 2014 Aug; 74(2):291-302. PubMed ID: 24908436
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA methylation and not H3K4 trimethylation dictates the expression status of miR-152 gene which inhibits migration of breast cancer cells via DNMT1/CDH1 loop.
    Sengupta D; Deb M; Rath SK; Kar S; Parbin S; Pradhan N; Patra SK
    Exp Cell Res; 2016 Aug; 346(2):176-87. PubMed ID: 27475839
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A regulatory circuit composed of DNA methyltransferases and receptor tyrosine kinases controls lung cancer cell aggressiveness.
    Yan F; Shen N; Pang J; Zhao N; Deng B; Li B; Yang Y; Yang P; Molina JR; Liu S
    Oncogene; 2017 Dec; 36(50):6919-6928. PubMed ID: 28869603
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor.
    Gray SG; Baird AM; O'Kelly F; Nikolaidis G; Almgren M; Meunier A; Dockry E; Hollywood D; Ekström TJ; Perry AS; O'Byrne KJ
    Int J Mol Med; 2012 Dec; 30(6):1505-11. PubMed ID: 23007409
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Promoter methylation status of tumor suppressor genes and inhibition of expression of DNA methyltransferase 1 in non-small cell lung cancer.
    Liu B; Song J; Luan J; Sun X; Bai J; Wang H; Li A; Zhang L; Feng X; Du Z
    Exp Biol Med (Maywood); 2016 Aug; 241(14):1531-9. PubMed ID: 27190263
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 5-aza-2'-deoxycytidine induces alterations in murine spermatogenesis and pregnancy outcome.
    Kelly TL; Li E; Trasler JM
    J Androl; 2003; 24(6):822-30. PubMed ID: 14581508
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Azacytidine and decitabine induce gene-specific and non-random DNA demethylation in human cancer cell lines.
    Hagemann S; Heil O; Lyko F; Brueckner B
    PLoS One; 2011 Mar; 6(3):e17388. PubMed ID: 21408221
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells.
    Suzuki M; Sunaga N; Shames DS; Toyooka S; Gazdar AF; Minna JD
    Cancer Res; 2004 May; 64(9):3137-43. PubMed ID: 15126351
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Efficacy of decitabine-loaded nanogels in overcoming cancer drug resistance is mediated via sustained DNA methyltransferase 1 (DNMT1) depletion.
    Vijayaraghavalu S; Labhasetwar V
    Cancer Lett; 2013 Apr; 331(1):122-9. PubMed ID: 23305699
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 5-aza-2'-deoxycytidine-induced genome rearrangements are mediated by DNMT1.
    Maslov AY; Lee M; Gundry M; Gravina S; Strogonova N; Tazearslan C; Bendebury A; Suh Y; Vijg J
    Oncogene; 2012 Dec; 31(50):5172-9. PubMed ID: 22349820
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.