BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 26091168)

  • 21. Non-colinear polyketide biosynthesis in the aureothin and neoaureothin pathways: an evolutionary perspective.
    Traitcheva N; Jenke-Kodama H; He J; Dittmann E; Hertweck C
    Chembiochem; 2007 Oct; 8(15):1841-9. PubMed ID: 17763486
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics.
    Tao M; Wang L; Wendt-Pienkowski E; George NP; Galm U; Zhang G; Coughlin JM; Shen B
    Mol Biosyst; 2007 Jan; 3(1):60-74. PubMed ID: 17216057
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Rational design and assembly of synthetic trimodular polyketide synthases.
    Menzella HG; Carney JR; Santi DV
    Chem Biol; 2007 Feb; 14(2):143-51. PubMed ID: 17317568
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Rational design of modular polyketide synthases: morphing the aureothin pathway into a luteoreticulin assembly line.
    Sugimoto Y; Ding L; Ishida K; Hertweck C
    Angew Chem Int Ed Engl; 2014 Feb; 53(6):1560-4. PubMed ID: 24402879
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Rational engineering acyltransferase domain of modular polyketide synthase for expanding substrate specificity.
    Zhang W; Zhou L; Li C; Deng Z; Qu X
    Methods Enzymol; 2019; 622():271-292. PubMed ID: 31155056
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cloning and analysis of a type II polyketide synthase gene cluster from Streptomyces toxytricini NRRL 15,443.
    Yoo A; Demirev AV; Lee JS; Kim SD; Nam DH
    J Microbiol; 2006 Dec; 44(6):649-54. PubMed ID: 17205043
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.
    Ward SL; Hu Z; Schirmer A; Reid R; Revill WP; Reeves CD; Petrakovsky OV; Dong SD; Katz L
    Antimicrob Agents Chemother; 2004 Dec; 48(12):4703-12. PubMed ID: 15561847
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.
    Rascher A; Hu Z; Buchanan GO; Reid R; Hutchinson CR
    Appl Environ Microbiol; 2005 Aug; 71(8):4862-71. PubMed ID: 16085885
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Probing the Flexibility of an Iterative Modular Polyketide Synthase with Non-Native Substrates in Vitro.
    Curran SC; Hagen A; Poust S; Chan LJG; Garabedian BM; de Rond T; Baluyot MJ; Vu JT; Lau AK; Yuzawa S; Petzold CJ; Katz L; Keasling JD
    ACS Chem Biol; 2018 Aug; 13(8):2261-2268. PubMed ID: 29912551
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A type I/type III polyketide synthase hybrid biosynthetic pathway for the structurally unique ansa compound kendomycin.
    Wenzel SC; Bode HB; Kochems I; Müller R
    Chembiochem; 2008 Nov; 9(16):2711-21. PubMed ID: 18972512
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Complete biosynthesis of erythromycin A and designed analogs using E. coli as a heterologous host.
    Zhang H; Wang Y; Wu J; Skalina K; Pfeifer BA
    Chem Biol; 2010 Nov; 17(11):1232-40. PubMed ID: 21095573
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Engineered biosynthesis of geldanamycin analogs for Hsp90 inhibition.
    Patel K; Piagentini M; Rascher A; Tian ZQ; Buchanan GO; Regentin R; Hu Z; Hutchinson CR; McDaniel R
    Chem Biol; 2004 Dec; 11(12):1625-33. PubMed ID: 15610846
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Heterologous Biosynthesis of Spinosad: An Omics-Guided Large Polyketide Synthase Gene Cluster Reconstitution in Streptomyces.
    Tan GY; Deng K; Liu X; Tao H; Chang Y; Chen J; Chen K; Sheng Z; Deng Z; Liu T
    ACS Synth Biol; 2017 Jun; 6(6):995-1005. PubMed ID: 28264562
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Heterologous Expression of a Cryptic Giant Type I PKS Gene Cluster Leads to the Production of Ansaseomycin.
    Liu SH; Wang W; Wang KB; Zhang B; Li W; Shi J; Jiao RH; Tan RX; Ge HM
    Org Lett; 2019 May; 21(10):3785-3788. PubMed ID: 31033301
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Herboxidiene biosynthesis, production, and structural modifications: prospect for hybrids with related polyketide.
    Pokhrel AR; Dhakal D; Jha AK; Sohng JK
    Appl Microbiol Biotechnol; 2015 Oct; 99(20):8351-62. PubMed ID: 26286508
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.
    Shin JC; Na Z; Lee DH; Kim WC; Lee K; Shen YM; Paik SG; Hong YS; Lee JJ
    J Microbiol Biotechnol; 2008 Jun; 18(6):1101-8. PubMed ID: 18600054
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.
    Wu Y; Kang Q; Shen Y; Su W; Bai L
    Mol Biosyst; 2011 Aug; 7(8):2459-69. PubMed ID: 21614382
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Alkyldihydropyrones, new polyketides synthesized by a type III polyketide synthase from Streptomyces reveromyceticus.
    Aizawa T; Kim SY; Takahashi S; Koshita M; Tani M; Futamura Y; Osada H; Funa N
    J Antibiot (Tokyo); 2014 Dec; 67(12):819-23. PubMed ID: 24984800
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Inactivation of putative PKS genes can double geldanamycin yield in Streptomyces hygroscopicus 17997.
    Li YH; Li M; He WQ; Wang YG; Shao RG
    Genet Mol Res; 2013 Jun; 12(2):2076-85. PubMed ID: 23913387
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Involvement of the Baeyer-Villiger Monooxygenase IfnQ in the Biosynthesis of Isofuranonaphthoquinone Scaffold of JBIR-76 and -77.
    Katsuyama Y; Sone K; Satou R; Izumikawa M; Takagi M; Fujie M; Satoh N; Shin-Ya K; Ohnishi Y
    Chembiochem; 2016 Jun; 17(11):1021-8. PubMed ID: 27158812
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.