BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1621 related articles for article (PubMed ID: 26093169)

  • 1. Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
    Paumier KL; Luk KC; Manfredsson FP; Kanaan NM; Lipton JW; Collier TJ; Steece-Collier K; Kemp CJ; Celano S; Schulz E; Sandoval IM; Fleming S; Dirr E; Polinski NK; Trojanowski JQ; Lee VM; Sortwell CE
    Neurobiol Dis; 2015 Oct; 82():185-199. PubMed ID: 26093169
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils.
    Patterson JR; Duffy MF; Kemp CJ; Howe JW; Collier TJ; Stoll AC; Miller KM; Patel P; Levine N; Moore DJ; Luk KC; Fleming SM; Kanaan NM; Paumier KL; El-Agnaf OMA; Sortwell CE
    Neurobiol Dis; 2019 Oct; 130():104525. PubMed ID: 31276792
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dose-related biphasic effect of the Parkinson's disease neurotoxin MPTP, on the spread, accumulation, and toxicity of α-synuclein.
    Merghani MM; Ardah MT; Al Shamsi M; Kitada T; Haque ME
    Neurotoxicology; 2021 May; 84():41-52. PubMed ID: 33549656
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
    Duffy MF; Collier TJ; Patterson JR; Kemp CJ; Luk KC; Tansey MG; Paumier KL; Kanaan NM; Fischer DL; Polinski NK; Barth OL; Howe JW; Vaikath NN; Majbour NK; El-Agnaf OMA; Sortwell CE
    J Neuroinflammation; 2018 May; 15(1):129. PubMed ID: 29716614
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.
    Recasens A; Dehay B; Bové J; Carballo-Carbajal I; Dovero S; Pérez-Villalba A; Fernagut PO; Blesa J; Parent A; Perier C; Fariñas I; Obeso JA; Bezard E; Vila M
    Ann Neurol; 2014 Mar; 75(3):351-62. PubMed ID: 24243558
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PET imaging reveals early and progressive dopaminergic deficits after intra-striatal injection of preformed alpha-synuclein fibrils in rats.
    Thomsen MB; Ferreira SA; Schacht AC; Jacobsen J; Simonsen M; Betzer C; Jensen PH; Brooks DJ; Landau AM; Romero-Ramos M
    Neurobiol Dis; 2021 Feb; 149():105229. PubMed ID: 33352233
    [TBL] [Abstract][Full Text] [Related]  

  • 7. AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson's disease.
    Ip CW; Klaus LC; Karikari AA; Visanji NP; Brotchie JM; Lang AE; Volkmann J; Koprich JB
    Acta Neuropathol Commun; 2017 Feb; 5(1):11. PubMed ID: 28143577
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes.
    Chu Y; Muller S; Tavares A; Barret O; Alagille D; Seibyl J; Tamagnan G; Marek K; Luk KC; Trojanowski JQ; Lee VMY; Kordower JH
    Brain; 2019 Nov; 142(11):3565-3579. PubMed ID: 31580415
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Loss of One Engrailed1 Allele Enhances Induced α-Synucleinopathy.
    Chatterjee D; Sanchez DS; Quansah E; Rey NL; George S; Becker K; Madaj Z; Steiner JA; Ma J; Escobar Galvis ML; Kordower JH; Brundin P
    J Parkinsons Dis; 2019; 9(2):315-326. PubMed ID: 30932894
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice.
    Luk KC; Kehm V; Carroll J; Zhang B; O'Brien P; Trojanowski JQ; Lee VM
    Science; 2012 Nov; 338(6109):949-53. PubMed ID: 23161999
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deficits in basal and evoked striatal dopamine release following alpha-synuclein preformed fibril injection: An in vivo microdialysis study.
    Centner A; Del Priore I; Chambers N; Cohen SR; Terry ML; Coyle M; Glinski J; Stoll AC; Patterson JR; Kemp CJ; Miller KM; Kubik M; Kuhn N; Luk KC; Sortwell CE; Bishop C
    Eur J Neurosci; 2024 Apr; 59(7):1585-1603. PubMed ID: 38356120
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions.
    Stoll AC; Kemp CJ; Patterson JR; Howe JW; Steece-Collier K; Luk KC; Sortwell CE; Benskey MJ
    Neurobiol Dis; 2024 Feb; 191():106411. PubMed ID: 38228253
    [TBL] [Abstract][Full Text] [Related]  

  • 13. α-Synuclein Propagation Mouse Models of Parkinson's Disease.
    Uemura N; Ueda J; Okuda S; Sawamura M; Takahashi R
    Methods Mol Biol; 2021; 2322():119-130. PubMed ID: 34043198
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Host-to-graft Propagation of α-synuclein in a Mouse Model of Parkinson's Disease: Intranigral Versus Intrastriatal Transplantation.
    Patrigeon M; Brot S; Bonnet ML; Belnoue L; Gaillard A
    Transplantation; 2023 Aug; 107(8):e201-e212. PubMed ID: 36944598
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparison of the behavioural and histological characteristics of the 6-OHDA and α-synuclein rat models of Parkinson's disease.
    Decressac M; Mattsson B; Björklund A
    Exp Neurol; 2012 May; 235(1):306-15. PubMed ID: 22394547
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression.
    Bourdenx M; Dovero S; Engeln M; Bido S; Bastide MF; Dutheil N; Vollenweider I; Baud L; Piron C; Grouthier V; Boraud T; Porras G; Li Q; Baekelandt V; Scheller D; Michel A; Fernagut PO; Georges F; Courtine G; Bezard E; Dehay B
    Acta Neuropathol Commun; 2015 Jul; 3():46. PubMed ID: 26205255
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Monoamine Oxidase-B Inhibition Facilitates α-Synuclein Secretion
    Nakamura Y; Arawaka S; Sato H; Sasaki A; Shigekiyo T; Takahata K; Tsunekawa H; Kato T
    J Neurosci; 2021 Sep; 41(35):7479-7491. PubMed ID: 34290084
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition.
    Stoll AC; Kemp CJ; Patterson JR; Kubik M; Kuhn N; Benskey M; Duffy MF; Luk KC; Sortwell CE
    J Neuroinflammation; 2024 Apr; 21(1):108. PubMed ID: 38664840
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Preformed fibrils generated from mouse alpha-synuclein produce more inclusion pathology in rats than fibrils generated from rat alpha-synuclein.
    Howe JW; Sortwell CE; Duffy MF; Kemp CJ; Russell CP; Kubik M; Patel P; Luk KC; El-Agnaf OMA; Patterson JR
    Parkinsonism Relat Disord; 2021 Aug; 89():41-47. PubMed ID: 34218047
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Unilateral intranigral administration of β-sitosterol β-D-glucoside triggers pathological α-synuclein spreading and bilateral nigrostriatal dopaminergic neurodegeneration in the rat.
    Soto-Rojas LO; Martínez-Dávila IA; Luna-Herrera C; Gutierrez-Castillo ME; Lopez-Salas FE; Gatica-Garcia B; Soto-Rodriguez G; Bringas Tobon ME; Flores G; Padilla-Viveros A; Bañuelos C; Blanco-Alvarez VM; Dávila-Ayala J; Reyes-Corona D; Garcés-Ramírez L; Hidalgo-Alegria O; De La Cruz-López F; Martinez-Fong D
    Acta Neuropathol Commun; 2020 Apr; 8(1):56. PubMed ID: 32321590
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 82.