BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

345 related articles for article (PubMed ID: 26094596)

  • 21. Novel beta-glucocerebrosidase chaperone compounds identified from cell-based screening reduce pathologically accumulated glucosylsphingosine in iPS-derived neuronal cells.
    Naito Y; Sakamoto S; Kojima T; Homma M; Tanaka M; Matsui H
    SLAS Discov; 2023 Oct; 28(7):344-349. PubMed ID: 37369311
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Oral ambroxol increases brain glucocerebrosidase activity in a nonhuman primate.
    Migdalska-Richards A; Ko WKD; Li Q; Bezard E; Schapira AHV
    Synapse; 2017 Jul; 71(7):. PubMed ID: 28295625
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cerebrospinal fluid β-glucocerebrosidase activity is reduced in parkinson's disease patients.
    Parnetti L; Paciotti S; Eusebi P; Dardis A; Zampieri S; Chiasserini D; Tasegian A; Tambasco N; Bembi B; Calabresi P; Beccari T
    Mov Disord; 2017 Oct; 32(10):1423-1431. PubMed ID: 28843015
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Ambroxol modulates 6-Hydroxydopamine-induced temporal reduction in Glucocerebrosidase (GCase) enzymatic activity and Parkinson's disease symptoms.
    Mishra A; Chandravanshi LP; Trigun SK; Krishnamurthy S
    Biochem Pharmacol; 2018 Sep; 155():479-493. PubMed ID: 30040928
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Molecular mechanisms of the ambroxol action in Gaucher disease and GBA1 mutation-associated Parkinson disease.
    Cyske Z; Gaffke L; Rintz E; Wiśniewska K; Węgrzyn G; Pierzynowska K
    Neurochem Int; 2024 May; 178():105774. PubMed ID: 38797393
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The LIMP-2/SCARB2 binding motif on acid β-glucosidase: basic and applied implications for Gaucher disease and associated neurodegenerative diseases.
    Liou B; Haffey WD; Greis KD; Grabowski GA
    J Biol Chem; 2014 Oct; 289(43):30063-74. PubMed ID: 25202012
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Reduced glucocerebrosidase activity in monocytes from patients with Parkinson's disease.
    Atashrazm F; Hammond D; Perera G; Dobson-Stone C; Mueller N; Pickford R; Kim WS; Kwok JB; Lewis SJG; Halliday GM; Dzamko N
    Sci Rep; 2018 Oct; 8(1):15446. PubMed ID: 30337601
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Dissociation of glucocerebrosidase dimer in solution by its co-factor, saposin C.
    Gruschus JM; Jiang Z; Yap TL; Hill SA; Grishaev A; Piszczek G; Sidransky E; Lee JC
    Biochem Biophys Res Commun; 2015 Feb; 457(4):561-6. PubMed ID: 25600808
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease.
    Murphy KE; Gysbers AM; Abbott SK; Tayebi N; Kim WS; Sidransky E; Cooper A; Garner B; Halliday GM
    Brain; 2014 Mar; 137(Pt 3):834-48. PubMed ID: 24477431
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Lysosome sorting of β-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor.
    Zhao Y; Ren J; Padilla-Parra S; Fry EE; Stuart DI
    Nat Commun; 2014 Jul; 5():4321. PubMed ID: 25027712
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models.
    Sanchez-Martinez A; Beavan M; Gegg ME; Chau KY; Whitworth AJ; Schapira AH
    Sci Rep; 2016 Aug; 6():31380. PubMed ID: 27539639
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.
    Mazzulli JR; Zunke F; Tsunemi T; Toker NJ; Jeon S; Burbulla LF; Patnaik S; Sidransky E; Marugan JJ; Sue CM; Krainc D
    J Neurosci; 2016 Jul; 36(29):7693-706. PubMed ID: 27445146
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Enhancing the Activity of Glucocerebrosidase as a Treatment for Parkinson Disease.
    Menozzi E; Schapira AHV
    CNS Drugs; 2020 Sep; 34(9):915-923. PubMed ID: 32607746
    [TBL] [Abstract][Full Text] [Related]  

  • 34. GBA1 mutations: Prospects for exosomal biomarkers in α-synuclein pathologies.
    Johnson PH; Weinreb NJ; Cloyd JC; Tuite PJ; Kartha RV
    Mol Genet Metab; 2020 Feb; 129(2):35-46. PubMed ID: 31761523
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Glucocerebrosidase Defects as a Major Risk Factor for Parkinson's Disease.
    Avenali M; Blandini F; Cerri S
    Front Aging Neurosci; 2020; 12():97. PubMed ID: 32372943
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Glucocerebrosidase and Parkinson disease: Recent advances.
    Schapira AH
    Mol Cell Neurosci; 2015 May; 66(Pt A):37-42. PubMed ID: 25802027
    [TBL] [Abstract][Full Text] [Related]  

  • 37. N370S-GBA1 mutation causes lysosomal cholesterol accumulation in Parkinson's disease.
    García-Sanz P; Orgaz L; Bueno-Gil G; Espadas I; Rodríguez-Traver E; Kulisevsky J; Gutierrez A; Dávila JC; González-Polo RA; Fuentes JM; Mir P; Vicario C; Moratalla R
    Mov Disord; 2017 Oct; 32(10):1409-1422. PubMed ID: 28779532
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Role of LIMP-2 in the intracellular trafficking of β-glucosidase in different human cellular models.
    Malini E; Zampieri S; Deganuto M; Romanello M; Sechi A; Bembi B; Dardis A
    FASEB J; 2015 Sep; 29(9):3839-52. PubMed ID: 26018676
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Interaction between parkin and mutant glucocerebrosidase variants: a possible link between Parkinson disease and Gaucher disease.
    Ron I; Rapaport D; Horowitz M
    Hum Mol Genet; 2010 Oct; 19(19):3771-81. PubMed ID: 20643691
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Selective loss of glucocerebrosidase activity in sporadic Parkinson's disease and dementia with Lewy bodies.
    Chiasserini D; Paciotti S; Eusebi P; Persichetti E; Tasegian A; Kurzawa-Akanbi M; Chinnery PF; Morris CM; Calabresi P; Parnetti L; Beccari T
    Mol Neurodegener; 2015 Mar; 10():15. PubMed ID: 25881142
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.