BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

481 related articles for article (PubMed ID: 26098424)

  • 1. Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate.
    Deval J; Hong J; Wang G; Taylor J; Smith LK; Fung A; Stevens SK; Liu H; Jin Z; Dyatkina N; Prhavc M; Stoycheva AD; Serebryany V; Liu J; Smith DB; Tam Y; Zhang Q; Moore ML; Fearns R; Chanda SM; Blatt LM; Symons JA; Beigelman L
    PLoS Pathog; 2015 Jun; 11(6):e1004995. PubMed ID: 26098424
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biochemical Effect of Resistance Mutations against Synergistic Inhibitors of RSV RNA Polymerase.
    Deval J; Fung A; Stevens SK; Jordan PC; Gromova T; Taylor JS; Hong J; Meng J; Wang G; Dyatkina N; Prhavc M; Symons JA; Beigelman L
    PLoS One; 2016; 11(5):e0154097. PubMed ID: 27163448
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of 4'-chloromethyl-2'-deoxy-3',5'-di-O-isobutyryl-2'-fluorocytidine (ALS-8176), a first-in-class RSV polymerase inhibitor for treatment of human respiratory syncytial virus infection.
    Wang G; Deval J; Hong J; Dyatkina N; Prhavc M; Taylor J; Fung A; Jin Z; Stevens SK; Serebryany V; Liu J; Zhang Q; Tam Y; Chanda SM; Smith DB; Symons JA; Blatt LM; Beigelman L
    J Med Chem; 2015 Feb; 58(4):1862-78. PubMed ID: 25667954
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New antiviral approaches for respiratory syncytial virus and other mononegaviruses: Inhibiting the RNA polymerase.
    Fearns R; Deval J
    Antiviral Res; 2016 Oct; 134():63-76. PubMed ID: 27575793
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation Pathway of a Nucleoside Analog Inhibiting Respiratory Syncytial Virus Polymerase.
    Jordan PC; Stevens SK; Tam Y; Pemberton RP; Chaudhuri S; Stoycheva AD; Dyatkina N; Wang G; Symons JA; Deval J; Beigelman L
    ACS Chem Biol; 2017 Jan; 12(1):83-91. PubMed ID: 28103684
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir.
    Tchesnokov EP; Feng JY; Porter DP; Götte M
    Viruses; 2019 Apr; 11(4):. PubMed ID: 30987343
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of an allosteric inhibitor class blocking RNA elongation by the respiratory syncytial virus polymerase complex.
    Cox RM; Toots M; Yoon JJ; Sourimant J; Ludeke B; Fearns R; Bourque E; Patti J; Lee E; Vernachio J; Plemper RK
    J Biol Chem; 2018 Oct; 293(43):16761-16777. PubMed ID: 30206124
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preclinical Characterization of PC786, an Inhaled Small-Molecule Respiratory Syncytial Virus L Protein Polymerase Inhibitor.
    Coates M; Brookes D; Kim YI; Allen H; Fordyce EAF; Meals EA; Colley T; Ciana CL; Parra GF; Sherbukhin V; Stockwell JA; Thomas JC; Hunt SF; Anderson-Dring L; Onions ST; Cass L; Murray PJ; Ito K; Strong P; DeVincenzo JP; Rapeport G
    Antimicrob Agents Chemother; 2017 Sep; 61(9):. PubMed ID: 28652242
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium.
    Brookes DW; Coates M; Allen H; Daly L; Constant S; Huang S; Hows M; Davis A; Cass L; Ayrton J; Knowles I; Strong P; Rapeport G; Ito K
    Br J Pharmacol; 2018 Jun; 175(12):2520-2534. PubMed ID: 29579332
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Respiratory syncytial virus-A dynamics and the effects of lumicitabine, a nucleoside viral replication inhibitor, in experimentally infected humans.
    Patel K; Kirkpatrick CM; Nieforth KA; Chanda S; Zhang Q; McClure M; Fry J; Symons JA; Blatt LM; Beigelman L; DeVincenzo JP; Huntjens DR; Smith PF
    J Antimicrob Chemother; 2019 Feb; 74(2):442-452. PubMed ID: 30376079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of Non-Nucleoside Inhibitors of the Respiratory Syncytial Virus Polymerase Complex.
    Jiménez-Somarribas A; Mao S; Yoon JJ; Weisshaar M; Cox RM; Marengo JR; Mitchell DG; Morehouse ZP; Yan D; Solis I; Liotta DC; Natchus MG; Plemper RK
    J Med Chem; 2017 Mar; 60(6):2305-2325. PubMed ID: 28245119
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and validation of small interfering RNA on respiratory syncytial virus M2-2 gene: A potential approach in RNA interference on viral replication.
    Chin VK; Atika Aziz NA; Hudu SA; Harmal NS; Syahrilnizam A; Jalilian FA; Zamberi S
    J Virol Methods; 2016 Oct; 236():117-125. PubMed ID: 27432115
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Construction and Characterization of a Recombinant Human Respiratory Syncytial Virus Encoding Enhanced Green Fluorescence Protein for Antiviral Drug Screening Assay.
    Xu M; Jiao YY; Fu YH; Jiang N; Zheng YB; Yan YF; Zhang M; Zheng YP; Zhu WY; Peng XL; He JS
    Biomed Res Int; 2018; 2018():8431243. PubMed ID: 29568767
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Verdinexor (KPT-335), a Selective Inhibitor of Nuclear Export, Reduces Respiratory Syncytial Virus Replication
    Jorquera PA; Mathew C; Pickens J; Williams C; Luczo JM; Tamir S; Ghildyal R; Tripp RA
    J Virol; 2019 Feb; 93(4):. PubMed ID: 30541831
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential antiviral activities of respiratory syncytial virus (RSV) inhibitors in human airway epithelium.
    Mirabelli C; Jaspers M; Boon M; Jorissen M; Koukni M; Bardiot D; Chaltin P; Marchand A; Neyts J; Jochmans D
    J Antimicrob Chemother; 2018 Jul; 73(7):1823-1829. PubMed ID: 29596680
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of novel respiratory syncytial virus inhibitors identified by high throughput screen.
    Laganas VA; Dunn EF; McLaughlin RE; Tiong-Yip CL; Yuzhakov O; Isabella VM; Hill P; Yu Q
    Antiviral Res; 2015 Mar; 115():71-4. PubMed ID: 25542974
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vivo evaluation of antiviral compounds on respiratory syncytial virus using a juvenile vervet monkey (Chlorocebus pygerythrus) infection model.
    Houspie L; Stevens H; Ngotho M; Keyaerts E; Ispas G; Verloes R; Van Ranst M; Maes P
    Methods Mol Biol; 2013; 1030():373-82. PubMed ID: 23821283
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Direct Inhibition of Cellular Fatty Acid Synthase Impairs Replication of Respiratory Syncytial Virus and Other Respiratory Viruses.
    Ohol YM; Wang Z; Kemble G; Duke G
    PLoS One; 2015; 10(12):e0144648. PubMed ID: 26659560
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Respiratory Syncytial Virus Inhibitor AZ-27 Differentially Inhibits Different Polymerase Activities at the Promoter.
    Noton SL; Nagendra K; Dunn EF; Mawhorter ME; Yu Q; Fearns R
    J Virol; 2015 Aug; 89(15):7786-98. PubMed ID: 25995255
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative Therapeutic Potential of ALX-0171 and Palivizumab against Respiratory Syncytial Virus Clinical Isolate Infection of Well-Differentiated Primary Pediatric Bronchial Epithelial Cell Cultures.
    Broadbent L; Parke HG; Ferguson LJ; Millar A; Shields MD; Detalle L; Power UF
    Antimicrob Agents Chemother; 2020 Jan; 64(2):. PubMed ID: 31767728
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.