344 related articles for article (PubMed ID: 26100075)
1. PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling.
Braccini L; Ciraolo E; Campa CC; Perino A; Longo DL; Tibolla G; Pregnolato M; Cao Y; Tassone B; Damilano F; Laffargue M; Calautti E; Falasca M; Norata GD; Backer JM; Hirsch E
Nat Commun; 2015 Jun; 6():7400. PubMed ID: 26100075
[TBL] [Abstract][Full Text] [Related]
2. Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.
Liu TY; Shi CX; Gao R; Sun HJ; Xiong XQ; Ding L; Chen Q; Li YH; Wang JJ; Kang YM; Zhu GQ
Clin Sci (Lond); 2015 Nov; 129(10):839-50. PubMed ID: 26201094
[TBL] [Abstract][Full Text] [Related]
3. Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4alpha pathway in insulin resistant mice.
De Souza CT; Frederico MJ; da Luz G; Cintra DE; Ropelle ER; Pauli JR; Velloso LA
J Physiol; 2010 Jun; 588(Pt 12):2239-53. PubMed ID: 20421289
[TBL] [Abstract][Full Text] [Related]
4. Keratin 8/18 regulation of insulin receptor signaling and trafficking in hepatocytes through a concerted phosphoinositide-dependent Akt and Rab5 modulation.
Roux A; Loranger A; Lavoie JN; Marceau N
FASEB J; 2017 Aug; 31(8):3555-3573. PubMed ID: 28442548
[TBL] [Abstract][Full Text] [Related]
5. Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes.
Valverde AM; Burks DJ; Fabregat I; Fisher TL; Carretero J; White MF; Benito M
Diabetes; 2003 Sep; 52(9):2239-48. PubMed ID: 12941762
[TBL] [Abstract][Full Text] [Related]
6. Akt2 influences glycogen synthase activity in human skeletal muscle through regulation of NH₂-terminal (sites 2 + 2a) phosphorylation.
Friedrichsen M; Birk JB; Richter EA; Ribel-Madsen R; Pehmøller C; Hansen BF; Beck-Nielsen H; Hirshman MF; Goodyear LJ; Vaag A; Poulsen P; Wojtaszewski JF
Am J Physiol Endocrinol Metab; 2013 Mar; 304(6):E631-9. PubMed ID: 23321478
[TBL] [Abstract][Full Text] [Related]
7. Glutamine administration promotes hepatic glucose homeostasis through regulating the PI3K/Akt pathway in high-fat diet-induced obese mice with limb ischemia.
Pitaloka DMI; Ko CH; Lin MT; Yeh SL; Yeh CL
Nutr Res; 2019 Aug; 68():45-53. PubMed ID: 31419579
[TBL] [Abstract][Full Text] [Related]
8. Fucosylated chondroitin sulfate from sea cucumber improves glucose metabolism and activates insulin signaling in the liver of insulin-resistant mice.
Hu SW; Tian YY; Chang YG; Li ZJ; Xue CH; Wang YM
J Med Food; 2014 Jul; 17(7):749-57. PubMed ID: 24949837
[TBL] [Abstract][Full Text] [Related]
9. Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity.
Alliouachene S; Bilanges B; Chicanne G; Anderson KE; Pearce W; Ali K; Valet C; Posor Y; Low PC; Chaussade C; Scudamore CL; Salamon RS; Backer JM; Stephens L; Hawkins PT; Payrastre B; Vanhaesebroeck B
Cell Rep; 2015 Dec; 13(9):1881-94. PubMed ID: 26655903
[TBL] [Abstract][Full Text] [Related]
10. Caulerpa lentillifera extract ameliorates insulin resistance and regulates glucose metabolism in C57BL/KsJ-db/db mice via PI3K/AKT signaling pathway in myocytes.
Sharma BR; Kim HJ; Rhyu DY
J Transl Med; 2015 Feb; 13():62. PubMed ID: 25889508
[TBL] [Abstract][Full Text] [Related]
11. WDFY2 Potentiates Hepatic Insulin Sensitivity and Controls Endosomal Localization of the Insulin Receptor and IRS1/2.
Zhang L; Li X; Zhang N; Yang X; Hou T; Fu W; Yuan F; Wang L; Wen H; Tian Y; Zhang H; Lu X; Zhu WG
Diabetes; 2020 Sep; 69(9):1887-1902. PubMed ID: 32641353
[TBL] [Abstract][Full Text] [Related]
12. Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice.
Alliouachene S; Bilanges B; Chaussade C; Pearce W; Foukas LC; Scudamore CL; Moniz LS; Vanhaesebroeck B
Diabetologia; 2016 Jul; 59(7):1503-1512. PubMed ID: 27138914
[TBL] [Abstract][Full Text] [Related]
13. Sanhuang xiexin decoction synergizes insulin/PI3K-Akt/FoxO signaling pathway to inhibit hepatic glucose production and alleviate T2DM.
Chen D; Chen X; He C; Xiao C; Chen Z; Chen Q; Chen J; Bo H
J Ethnopharmacol; 2023 Apr; 306():116162. PubMed ID: 36646159
[TBL] [Abstract][Full Text] [Related]
14. Dietary Lycium barbarum polysaccharide induces Nrf2/ARE pathway and ameliorates insulin resistance induced by high-fat via activation of PI3K/AKT signaling.
Yang Y; Li W; Li Y; Wang Q; Gao L; Zhao J
Oxid Med Cell Longev; 2014; 2014():145641. PubMed ID: 25045414
[TBL] [Abstract][Full Text] [Related]
15. Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1.
Lu M; Wan M; Leavens KF; Chu Q; Monks BR; Fernandez S; Ahima RS; Ueki K; Kahn CR; Birnbaum MJ
Nat Med; 2012 Feb; 18(3):388-95. PubMed ID: 22344295
[TBL] [Abstract][Full Text] [Related]
16. Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes.
Veilleux A; Houde VP; Bellmann K; Marette A
Mol Endocrinol; 2010 Apr; 24(4):766-78. PubMed ID: 20203102
[TBL] [Abstract][Full Text] [Related]
17. Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance.
Sajan MP; Lee MC; Foufelle F; Sajan J; Cleland C; Farese RV
Cell Signal; 2018 Mar; 43():62-70. PubMed ID: 29269047
[TBL] [Abstract][Full Text] [Related]
18. Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS.
Molinaro A; Becattini B; Mazzoli A; Bleve A; Radici L; Maxvall I; Sopasakis VR; Molinaro A; Bäckhed F; Solinas G
Cell Metab; 2019 Jun; 29(6):1400-1409.e5. PubMed ID: 30982732
[TBL] [Abstract][Full Text] [Related]
19. Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake.
Green CJ; Göransson O; Kular GS; Leslie NR; Gray A; Alessi DR; Sakamoto K; Hundal HS
J Biol Chem; 2008 Oct; 283(41):27653-27667. PubMed ID: 18669636
[TBL] [Abstract][Full Text] [Related]
20. Stimulation of glycogen synthesis by insulin requires S6 kinase and phosphatidylinositol-3-kinase in HTC-IR cells.
Sánchez-Margalet V
J Cell Physiol; 2000 Feb; 182(2):182-8. PubMed ID: 10623881
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]