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2. Disease-related Huntingtin seeding activities in cerebrospinal fluids of Huntington's disease patients. Lee CYD; Wang N; Shen K; Stricos M; Langfelder P; Cheon KH; Cortés EP; Vinters HV; Vonsattel JP; Wexler NS; Damoiseaux R; Frydman J; Yang XW Sci Rep; 2020 Nov; 10(1):20295. PubMed ID: 33219289 [TBL] [Abstract][Full Text] [Related]
3. Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat. Clemens LE; Weber JJ; Wlodkowski TT; Yu-Taeger L; Michaud M; Calaminus C; Eckert SH; Gaca J; Weiss A; Magg JC; Jansson EK; Eckert GP; Pichler BJ; Bordet T; Pruss RM; Riess O; Nguyen HP Brain; 2015 Dec; 138(Pt 12):3632-53. PubMed ID: 26490331 [TBL] [Abstract][Full Text] [Related]
4. Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients. Wild EJ; Boggio R; Langbehn D; Robertson N; Haider S; Miller JR; Zetterberg H; Leavitt BR; Kuhn R; Tabrizi SJ; Macdonald D; Weiss A J Clin Invest; 2015 May; 125(5):1979-86. PubMed ID: 25844897 [TBL] [Abstract][Full Text] [Related]
5. Multidrug resistance protein 1 reduces the aggregation of mutant huntingtin in neuronal cells derived from the Huntington's disease R6/2 model. Im W; Ban JJ; Chung JY; Lee ST; Chu K; Kim M Sci Rep; 2015 Nov; 5():16887. PubMed ID: 26586297 [TBL] [Abstract][Full Text] [Related]
6. A novel human embryonic stem cell-derived Huntington's disease neuronal model exhibits mutant huntingtin (mHTT) aggregates and soluble mHTT-dependent neurodegeneration. Lu B; Palacino J FASEB J; 2013 May; 27(5):1820-9. PubMed ID: 23325320 [TBL] [Abstract][Full Text] [Related]
7. Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease. Caron NS; Banos R; Yanick C; Aly AE; Byrne LM; Smith ED; Xie Y; Smith SEP; Potluri N; Findlay Black H; Casal L; Ko S; Cheung D; Kim H; Seong IS; Wild EJ; Song JJ; Hayden MR; Southwell AL J Neurosci; 2021 Jan; 41(4):780-796. PubMed ID: 33310753 [TBL] [Abstract][Full Text] [Related]
8. Huntington's disease does not appear to increase the risk of diabetes mellitus. Boesgaard TW; Nielsen TT; Josefsen K; Hansen T; Jørgensen T; Pedersen O; Nørremølle A; Nielsen JE; Hasholt L J Neuroendocrinol; 2009 Sep; 21(9):770-6. PubMed ID: 19602103 [TBL] [Abstract][Full Text] [Related]
9. Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models. Sontag EM; Lotz GP; Agrawal N; Tran A; Aron R; Yang G; Necula M; Lau A; Finkbeiner S; Glabe C; Marsh JL; Muchowski PJ; Thompson LM J Neurosci; 2012 Aug; 32(32):11109-19. PubMed ID: 22875942 [TBL] [Abstract][Full Text] [Related]
10. Transgenic animal models for study of the pathogenesis of Huntington's disease and therapy. Chang R; Liu X; Li S; Li XJ Drug Des Devel Ther; 2015; 9():2179-88. PubMed ID: 25931812 [TBL] [Abstract][Full Text] [Related]
11. Validation of Ultrasensitive Mutant Huntingtin Detection in Human Cerebrospinal Fluid by Single Molecule Counting Immunoassay. Fodale V; Boggio R; Daldin M; Cariulo C; Spiezia MC; Byrne LM; Leavitt BR; Wild EJ; Macdonald D; Weiss A; Bresciani A J Huntingtons Dis; 2017; 6(4):349-361. PubMed ID: 29125493 [TBL] [Abstract][Full Text] [Related]
13. [Huntington disease. A review]. Bonilla E Invest Clin; 2000 Jun; 41(2):117-41. PubMed ID: 10961047 [TBL] [Abstract][Full Text] [Related]
14. Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington's disease mice. Caron NS; Byrne LM; Lemarié FL; Bone JN; Aly AE; Ko S; Anderson C; Casal LL; Hill AM; Hawellek DJ; McColgan P; Wild EJ; Leavitt BR; Hayden MR Transl Neurodegener; 2024 Oct; 13(1):50. PubMed ID: 39380076 [TBL] [Abstract][Full Text] [Related]
15. Nucleocytoplasmic trafficking and transcription effects of huntingtin in Huntington's disease. Truant R; Atwal RS; Burtnik A Prog Neurobiol; 2007 Nov; 83(4):211-27. PubMed ID: 17240517 [TBL] [Abstract][Full Text] [Related]
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18. Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography. Darrow MC; Sergeeva OA; Isas JM; Galaz-Montoya JG; King JA; Langen R; Schmid MF; Chiu W J Biol Chem; 2015 Jul; 290(28):17451-61. PubMed ID: 25995452 [TBL] [Abstract][Full Text] [Related]
19. Inhibition of Aggregation of Mutant Huntingtin by Nucleic Acid Aptamers In Vitro and in a Yeast Model of Huntington's Disease. Chaudhary RK; Patel KA; Patel MK; Joshi RH; Roy I Mol Ther; 2015 Dec; 23(12):1912-26. PubMed ID: 26310631 [TBL] [Abstract][Full Text] [Related]
20. Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction. Goswami A; Dikshit P; Mishra A; Mulherkar S; Nukina N; Jana NR Biochem Biophys Res Commun; 2006 Mar; 342(1):184-90. PubMed ID: 16472774 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]