These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

274 related articles for article (PubMed ID: 26101257)

  • 1. SAMHD1 is a single-stranded nucleic acid binding protein with no active site-associated nuclease activity.
    Seamon KJ; Sun Z; Shlyakhtenko LS; Lyubchenko YL; Stivers JT
    Nucleic Acids Res; 2015 Jul; 43(13):6486-99. PubMed ID: 26101257
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Guanine-containing ssDNA and RNA induce dimeric and tetrameric structural forms of SAMHD1.
    Orris B; Sung MW; Bhat S; Xu Y; Huynh KW; Han S; Johnson DC; Bosbach B; Shields DJ; Stivers JT
    Nucleic Acids Res; 2023 Dec; 51(22):12443-12458. PubMed ID: 37930833
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Single-Stranded Nucleic Acids Bind to the Tetramer Interface of SAMHD1 and Prevent Formation of the Catalytic Homotetramer.
    Seamon KJ; Bumpus NN; Stivers JT
    Biochemistry; 2016 Nov; 55(44):6087-6099. PubMed ID: 27775344
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis of allosteric activation of sterile α motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates.
    Koharudin LM; Wu Y; DeLucia M; Mehrens J; Gronenborn AM; Ahn J
    J Biol Chem; 2014 Nov; 289(47):32617-27. PubMed ID: 25288794
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.
    Beloglazova N; Flick R; Tchigvintsev A; Brown G; Popovic A; Nocek B; Yakunin AF
    J Biol Chem; 2013 Mar; 288(12):8101-8110. PubMed ID: 23364794
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Guanine-containing ssDNA and RNA induce dimeric and tetrameric SAMHD1 in cryo-EM and binding studies.
    Orris B; Sung MW; Bhat S; Xu Y; Huynh KW; Han S; Johnson DC; Bosbach B; Shields DJ; Stivers JT
    bioRxiv; 2023 Jun; ():. PubMed ID: 37398126
    [TBL] [Abstract][Full Text] [Related]  

  • 7. GTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated state.
    Hansen EC; Seamon KJ; Cravens SL; Stivers JT
    Proc Natl Acad Sci U S A; 2014 May; 111(18):E1843-51. PubMed ID: 24753578
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis of cellular dNTP regulation by SAMHD1.
    Ji X; Tang C; Zhao Q; Wang W; Xiong Y
    Proc Natl Acad Sci U S A; 2014 Oct; 111(41):E4305-14. PubMed ID: 25267621
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase.
    Zhu C; Gao W; Zhao K; Qin X; Zhang Y; Peng X; Zhang L; Dong Y; Zhang W; Li P; Wei W; Gong Y; Yu XF
    Nat Commun; 2013; 4():2722. PubMed ID: 24217394
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Allosteric Activation of SAMHD1 Protein by Deoxynucleotide Triphosphate (dNTP)-dependent Tetramerization Requires dNTP Concentrations That Are Similar to dNTP Concentrations Observed in Cycling T Cells.
    Wang Z; Bhattacharya A; Villacorta J; Diaz-Griffero F; Ivanov DN
    J Biol Chem; 2016 Oct; 291(41):21407-21413. PubMed ID: 27566548
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deoxyguanosine-Linked Bifunctional Inhibitor of SAMHD1 dNTPase Activity and Nucleic Acid Binding.
    Egleston M; Dong L; Howlader AH; Bhat S; Orris B; Bianchet MA; Greenberg MM; Stivers JT
    ACS Chem Biol; 2023 Oct; 18(10):2200-2210. PubMed ID: 37233733
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The ribonuclease activity of SAMHD1 is required for HIV-1 restriction.
    Ryoo J; Choi J; Oh C; Kim S; Seo M; Kim SY; Seo D; Kim J; White TE; Brandariz-Nuñez A; Diaz-Griffero F; Yun CH; Hollenbaugh JA; Kim B; Baek D; Ahn K
    Nat Med; 2014 Aug; 20(8):936-41. PubMed ID: 25038827
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural Insights into the High-efficiency Catalytic Mechanism of the Sterile α-Motif/Histidine-Aspartate Domain-containing Protein.
    Li Y; Kong J; Peng X; Hou W; Qin X; Yu XF
    J Biol Chem; 2015 Dec; 290(49):29428-37. PubMed ID: 26438820
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTP.
    Zhu CF; Wei W; Peng X; Dong YH; Gong Y; Yu XF
    Acta Crystallogr D Biol Crystallogr; 2015 Mar; 71(Pt 3):516-24. PubMed ID: 25760601
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CyclinA2-Cyclin-dependent Kinase Regulates SAMHD1 Protein Phosphohydrolase Domain.
    Yan J; Hao C; DeLucia M; Swanson S; Florens L; Washburn MP; Ahn J; Skowronski J
    J Biol Chem; 2015 May; 290(21):13279-92. PubMed ID: 25847232
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allosteric regulation of the human and mouse deoxyribonucleotide triphosphohydrolase sterile α-motif/histidine-aspartate domain-containing protein 1 (SAMHD1).
    Miazzi C; Ferraro P; Pontarin G; Rampazzo C; Reichard P; Bianchi V
    J Biol Chem; 2014 Jun; 289(26):18339-46. PubMed ID: 24828500
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.
    Goldstone DC; Ennis-Adeniran V; Hedden JJ; Groom HC; Rice GI; Christodoulou E; Walker PA; Kelly G; Haire LF; Yap MW; de Carvalho LP; Stoye JP; Crow YJ; Taylor IA; Webb M
    Nature; 2011 Nov; 480(7377):379-82. PubMed ID: 22056990
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Uncovering allostery and regulation in SAMHD1 through molecular dynamics simulations.
    Patra KK; Bhattacharya A; Bhattacharya S
    Proteins; 2017 Jul; 85(7):1266-1275. PubMed ID: 28321930
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation.
    St Gelais C; Kim SH; Maksimova VV; Buzovetsky O; Knecht KM; Shepard C; Kim B; Xiong Y; Wu L
    J Virol; 2018 Mar; 92(6):. PubMed ID: 29321329
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SAMHD1, the Aicardi-Goutières syndrome gene and retroviral restriction factor, is a phosphorolytic ribonuclease rather than a hydrolytic ribonuclease.
    Ryoo J; Hwang SY; Choi J; Oh C; Ahn K
    Biochem Biophys Res Commun; 2016 Sep; 477(4):977-981. PubMed ID: 27387229
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.