BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

719 related articles for article (PubMed ID: 26111938)

  • 1. Uncoupling of endothelial nitric oxide synthase in cerebral vasculature of Tg2576 mice.
    Santhanam AV; d'Uscio LV; He T; Das P; Younkin SG; Katusic ZS
    J Neurochem; 2015 Sep; 134(6):1129-38. PubMed ID: 26111938
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of PPARδ prevents endothelial dysfunction induced by overexpression of amyloid-β precursor protein.
    d'Uscio LV; Das P; Santhanam AV; He T; Younkin SG; Katusic ZS
    Cardiovasc Res; 2012 Dec; 96(3):504-12. PubMed ID: 22886847
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Erythropoietin increases bioavailability of tetrahydrobiopterin and protects cerebral microvasculature against oxidative stress induced by eNOS uncoupling.
    Santhanam AV; d'Uscio LV; Katusic ZS
    J Neurochem; 2014 Nov; 131(4):521-9. PubMed ID: 25041251
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PPARδ agonist GW501516 prevents uncoupling of endothelial nitric oxide synthase in cerebral microvessels of hph-1 mice.
    Santhanam AV; d'Uscio LV; He T; Katusic ZS
    Brain Res; 2012 Nov; 1483():89-95. PubMed ID: 22982594
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I.
    Santhanam AV; d'Uscio LV; Katusic ZS
    Brain Res; 2015 Nov; 1625():198-205. PubMed ID: 26343845
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling.
    Schmidt K; Kolesnik B; Gorren AC; Werner ER; Mayer B
    Biochem Pharmacol; 2014 Aug; 90(3):246-53. PubMed ID: 24863258
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase.
    Chalupsky K; Cai H
    Proc Natl Acad Sci U S A; 2005 Jun; 102(25):9056-61. PubMed ID: 15941833
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.
    Crabtree MJ; Tatham AL; Hale AB; Alp NJ; Channon KM
    J Biol Chem; 2009 Oct; 284(41):28128-28136. PubMed ID: 19666465
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes.
    Bitar MS; Wahid S; Mustafa S; Al-Saleh E; Dhaunsi GS; Al-Mulla F
    Eur J Pharmacol; 2005 Mar; 511(1):53-64. PubMed ID: 15777779
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tetrahydrobiopterin, but not L-arginine, decreases NO synthase uncoupling in cells expressing high levels of endothelial NO synthase.
    Bevers LM; Braam B; Post JA; van Zonneveld AJ; Rabelink TJ; Koomans HA; Verhaar MC; Joles JA
    Hypertension; 2006 Jan; 47(1):87-94. PubMed ID: 16344367
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression.
    Bendall JK; Alp NJ; Warrick N; Cai S; Adlam D; Rockett K; Yokoyama M; Kawashima S; Channon KM
    Circ Res; 2005 Oct; 97(9):864-71. PubMed ID: 16179591
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerization.
    Benson MA; Batchelor H; Chuaiphichai S; Bailey J; Zhu H; Stuehr DJ; Bhattacharya S; Channon KM; Crabtree MJ
    J Biol Chem; 2013 Oct; 288(41):29836-45. PubMed ID: 23965989
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Folic Acid Promotes Recycling of Tetrahydrobiopterin and Protects Against Hypoxia-Induced Pulmonary Hypertension by Recoupling Endothelial Nitric Oxide Synthase.
    Chalupsky K; Kračun D; Kanchev I; Bertram K; Görlach A
    Antioxid Redox Signal; 2015 Nov; 23(14):1076-91. PubMed ID: 26414244
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Uncoupling of eNOS causes superoxide anion production and impairs NO signaling in the cerebral microvessels of hph-1 mice.
    Santhanam AV; d'Uscio LV; Smith LA; Katusic ZS
    J Neurochem; 2012 Sep; 122(6):1211-8. PubMed ID: 22784235
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.
    Crabtree MJ; Tatham AL; Al-Wakeel Y; Warrick N; Hale AB; Cai S; Channon KM; Alp NJ
    J Biol Chem; 2009 Jan; 284(2):1136-44. PubMed ID: 19011239
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Uncoupling of eNOS contributes to redox-sensitive leukocyte recruitment and microvascular leakage elicited by methylglyoxal.
    Su Y; Qadri SM; Hossain M; Wu L; Liu L
    Biochem Pharmacol; 2013 Dec; 86(12):1762-74. PubMed ID: 24144633
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Endothelial cell superoxide anion radical generation is not dependent on endothelial nitric oxide synthase-serine 1179 phosphorylation and endothelial nitric oxide synthase dimer/monomer distribution.
    Whitsett J; Martásek P; Zhao H; Schauer DW; Hatakeyama K; Kalyanaraman B; Vásquez-Vivar J
    Free Radic Biol Med; 2006 Jun; 40(11):2056-68. PubMed ID: 16716906
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Erythropoietin prevents endothelial dysfunction in GTP-cyclohydrolase I-deficient hph1 mice.
    dʼUscio LV; Santhanam AV; Katusic ZS
    J Cardiovasc Pharmacol; 2014 Dec; 64(6):514-21. PubMed ID: 25490417
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells.
    Sugiyama T; Levy BD; Michel T
    J Biol Chem; 2009 May; 284(19):12691-700. PubMed ID: 19286667
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endothelial dysfunction in rat adjuvant-induced arthritis: vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase.
    Haruna Y; Morita Y; Komai N; Yada T; Sakuta T; Tomita N; Fox DA; Kashihara N
    Arthritis Rheum; 2006 Jun; 54(6):1847-55. PubMed ID: 16729278
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.