142 related articles for article (PubMed ID: 26114812)
1. Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors.
Rupiani S; Buonfiglio R; Manerba M; Di Ianni L; Vettraino M; Giacomini E; Masetti M; Falchi F; Di Stefano G; Roberti M; Recanatini M
Eur J Med Chem; 2015 Aug; 101():63-70. PubMed ID: 26114812
[TBL] [Abstract][Full Text] [Related]
2. Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1.
Vettraino M; Manerba M; Govoni M; Di Stefano G
Anticancer Drugs; 2013 Sep; 24(8):862-70. PubMed ID: 23797802
[TBL] [Abstract][Full Text] [Related]
3. Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.
Granchi C; Roy S; Giacomelli C; Macchia M; Tuccinardi T; Martinelli A; Lanza M; Betti L; Giannaccini G; Lucacchini A; Funel N; León LG; Giovannetti E; Peters GJ; Palchaudhuri R; Calvaresi EC; Hergenrother PJ; Minutolo F
J Med Chem; 2011 Mar; 54(6):1599-612. PubMed ID: 21332213
[TBL] [Abstract][Full Text] [Related]
4. Identification of a potent inhibitor targeting human lactate dehydrogenase A and its metabolic modulation for cancer cell line.
Chen CY; Feng Y; Chen JY; Deng H
Bioorg Med Chem Lett; 2016 Jan; 26(1):72-5. PubMed ID: 26597536
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of lactate dehydrogenase activity as an approach to cancer therapy.
Fiume L; Manerba M; Vettraino M; Di Stefano G
Future Med Chem; 2014 Mar; 6(4):429-45. PubMed ID: 24635523
[TBL] [Abstract][Full Text] [Related]
6. Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase.
Manerba M; Vettraino M; Fiume L; Di Stefano G; Sartini A; Giacomini E; Buonfiglio R; Roberti M; Recanatini M
ChemMedChem; 2012 Feb; 7(2):311-7. PubMed ID: 22052811
[TBL] [Abstract][Full Text] [Related]
7. Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase.
Dragovich PS; Fauber BP; Boggs J; Chen J; Corson LB; Ding CZ; Eigenbrot C; Ge H; Giannetti AM; Hunsaker T; Labadie S; Li C; Liu Y; Liu Y; Ma S; Malek S; Peterson D; Pitts KE; Purkey HE; Robarge K; Salphati L; Sideris S; Ultsch M; VanderPorten E; Wang J; Wei B; Xu Q; Yen I; Yue Q; Zhang H; Zhang X; Zhou A
Bioorg Med Chem Lett; 2014 Aug; 24(16):3764-71. PubMed ID: 25037916
[TBL] [Abstract][Full Text] [Related]
8. Evaluation on the inhibition of pyrrol-2-yl ethanone derivatives to lactate dehydrogenase and anticancer activities.
Lu NN; Weng ZY; Chen QY; Boison D; Xiao XX; Gao J
Spectrochim Acta A Mol Biomol Spectrosc; 2016 Aug; 165():21-25. PubMed ID: 27104676
[TBL] [Abstract][Full Text] [Related]
9. Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.
Chaube B; Malvi P; Singh SV; Mohammad N; Meena AS; Bhat MK
Oncotarget; 2015 Nov; 6(35):37281-99. PubMed ID: 26484566
[TBL] [Abstract][Full Text] [Related]
10. Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors.
Kohlmann A; Zech SG; Li F; Zhou T; Squillace RM; Commodore L; Greenfield MT; Lu X; Miller DP; Huang WS; Qi J; Thomas RM; Wang Y; Zhang S; Dodd R; Liu S; Xu R; Xu Y; Miret JJ; Rivera V; Clackson T; Shakespeare WC; Zhu X; Dalgarno DC
J Med Chem; 2013 Feb; 56(3):1023-40. PubMed ID: 23302067
[TBL] [Abstract][Full Text] [Related]
11. Effects of the suppression of lactate dehydrogenase A on the growth and invasion of human gastric cancer cells.
Liu X; Yang Z; Chen Z; Chen R; Zhao D; Zhou Y; Qiao L
Oncol Rep; 2015 Jan; 33(1):157-62. PubMed ID: 25394466
[TBL] [Abstract][Full Text] [Related]
12. Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes.
Manerba M; Di Ianni L; Fiume L; Roberti M; Recanatini M; Di Stefano G
Eur J Pharm Sci; 2015 Jul; 74():95-102. PubMed ID: 25930121
[TBL] [Abstract][Full Text] [Related]
13. Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds.
Granchi C; Calvaresi EC; Tuccinardi T; Paterni I; Macchia M; Martinelli A; Hergenrother PJ; Minutolo F
Org Biomol Chem; 2013 Oct; 11(38):6588-96. PubMed ID: 23986182
[TBL] [Abstract][Full Text] [Related]
14. Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.
Kolappan S; Shen DL; Mosi R; Sun J; McEachern EJ; Vocadlo DJ; Craig L
Acta Crystallogr D Biol Crystallogr; 2015 Feb; 71(Pt 2):185-95. PubMed ID: 25664730
[TBL] [Abstract][Full Text] [Related]
15. N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation.
Granchi C; Roy S; De Simone A; Salvetti I; Tuccinardi T; Martinelli A; Macchia M; Lanza M; Betti L; Giannaccini G; Lucacchini A; Giovannetti E; Sciarrillo R; Peters GJ; Minutolo F
Eur J Med Chem; 2011 Nov; 46(11):5398-407. PubMed ID: 21944286
[TBL] [Abstract][Full Text] [Related]
16. Dual targeting of the Warburg effect with a glucose-conjugated lactate dehydrogenase inhibitor.
Calvaresi EC; Granchi C; Tuccinardi T; Di Bussolo V; Huigens RW; Lee HY; Palchaudhuri R; Macchia M; Martinelli A; Minutolo F; Hergenrother PJ
Chembiochem; 2013 Nov; 14(17):2263-7. PubMed ID: 24174263
[TBL] [Abstract][Full Text] [Related]
17. Characterization of the Saffron Derivative Crocetin as an Inhibitor of Human Lactate Dehydrogenase 5 in the Antiglycolytic Approach against Cancer.
Granchi C; Fortunato S; Meini S; Rizzolio F; Caligiuri I; Tuccinardi T; Lee HY; Hergenrother PJ; Minutolo F
J Agric Food Chem; 2017 Jul; 65(28):5639-5649. PubMed ID: 28643510
[TBL] [Abstract][Full Text] [Related]
18. Oxamic acid analogues as LDH-C4-specific competitive inhibitors.
Rodríguez-Páez L; Chena-Taboada MA; Cabrera-Hernández A; Cordero-Martínez J; Wong C
J Enzyme Inhib Med Chem; 2011 Aug; 26(4):579-86. PubMed ID: 21438710
[TBL] [Abstract][Full Text] [Related]
19. Identification and optimization of hydrazone-gallate derivatives as specific inhibitors of DNA methyltransferase 3A.
Erdmann A; Menon Y; Gros C; Masson V; Aussagues Y; Ausseil F; Novosad N; Schambel P; Baltas M; Arimondo PB
Future Med Chem; 2016; 8(4):373-80. PubMed ID: 26976348
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of N-acylhydrazones as inhibitors of MurC and MurD ligases.
Sink R; Kovac A; Tomasić T; Rupnik V; Boniface A; Bostock J; Chopra I; Blanot D; Masic LP; Gobec S; Zega A
ChemMedChem; 2008 Sep; 3(9):1362-70. PubMed ID: 18651694
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
