BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

344 related articles for article (PubMed ID: 26116172)

  • 1. YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors.
    Stachelek GC; Peterson-Roth E; Liu Y; Fernandez RJ; Pike LR; Qian JM; Abriola L; Hoyer D; Hungerford W; Merkel J; Glazer PM
    Mol Cancer Res; 2015 Oct; 13(10):1389-97. PubMed ID: 26116172
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library.
    Lally BE; Geiger GA; Kridel S; Arcury-Quandt AE; Robbins ME; Kock ND; Wheeler K; Peddi P; Georgakilas A; Kao GD; Koumenis C
    Cancer Res; 2007 Sep; 67(18):8791-9. PubMed ID: 17875720
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Poly(ADP-ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets.
    Chalmers AJ; Lakshman M; Chan N; Bristow RG
    Semin Radiat Oncol; 2010 Oct; 20(4):274-81. PubMed ID: 20832020
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair.
    Löser DA; Shibata A; Shibata AK; Woodbine LJ; Jeggo PA; Chalmers AJ
    Mol Cancer Ther; 2010 Jun; 9(6):1775-87. PubMed ID: 20530711
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441.
    Zhao Y; Thomas HD; Batey MA; Cowell IG; Richardson CJ; Griffin RJ; Calvert AH; Newell DR; Smith GC; Curtin NJ
    Cancer Res; 2006 May; 66(10):5354-62. PubMed ID: 16707462
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas.
    Czyż M; Toma M; Gajos-Michniewicz A; Majchrzak K; Hoser G; Szemraj J; Nieborowska-Skorska M; Cheng P; Gritsyuk D; Levesque M; Dummer R; Sliwinski T; Skorski T
    Oncotarget; 2016 Nov; 7(46):75551-75560. PubMed ID: 27705909
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparison of the effect of three different topoisomerase II inhibitors combined with cisplatin in human glioblastoma cells sensitized with double strand break repair inhibitors.
    Macieja A; Kopa P; Galita G; Pastwa E; Majsterek I; Poplawski T
    Mol Biol Rep; 2019 Aug; 46(4):3625-3636. PubMed ID: 31020489
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potentiation of Peptide Receptor Radionuclide Therapy by the PARP Inhibitor Olaparib.
    Nonnekens J; van Kranenburg M; Beerens CE; Suker M; Doukas M; van Eijck CH; de Jong M; van Gent DC
    Theranostics; 2016; 6(11):1821-32. PubMed ID: 27570553
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.
    Calabrese CR; Almassy R; Barton S; Batey MA; Calvert AH; Canan-Koch S; Durkacz BW; Hostomsky Z; Kumpf RA; Kyle S; Li J; Maegley K; Newell DR; Notarianni E; Stratford IJ; Skalitzky D; Thomas HD; Wang LZ; Webber SE; Williams KJ; Curtin NJ
    J Natl Cancer Inst; 2004 Jan; 96(1):56-67. PubMed ID: 14709739
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A preclinical study combining the DNA repair inhibitor Dbait with radiotherapy for the treatment of melanoma.
    Biau J; Devun F; Jdey W; Kotula E; Quanz M; Chautard E; Sayarath M; Sun JS; Verrelle P; Dutreix M
    Neoplasia; 2014 Oct; 16(10):835-44. PubMed ID: 25379020
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Poly (ADP-ribose) polymerase inhibitors sensitize cancer cells to hypofractionated radiotherapy through altered selection of DNA double-strand break repair pathways.
    Seo Y; Tamari K; Takahashi Y; Minami K; Tatekawa S; Isohashi F; Suzuki O; Akino Y; Ogawa K
    Int J Radiat Biol; 2022; 98(7):1222-1234. PubMed ID: 34919022
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [From poly(ADP-ribose) discovery to PARP inhibitors in cancer therapy].
    Schreiber V; Illuzzi G; Héberlé E; Dantzer F
    Bull Cancer; 2015 Oct; 102(10):863-73. PubMed ID: 26384693
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro and in vivo radiosensitization of colorectal cancer HT-29 cells by the smac mimetic JP-1201.
    Huerta S; Gao X; Livingston EH; Kapur P; Sun H; Anthony T
    Surgery; 2010 Aug; 148(2):346-53. PubMed ID: 20633731
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Exploiting the Achilles heel of cancer: the therapeutic potential of poly(ADP-ribose) polymerase inhibitors in BRCA2-defective cancer.
    Kyle S; Thomas HD; Mitchell J; Curtin NJ
    Br J Radiol; 2008 Oct; 81 Spec No 1():S6-11. PubMed ID: 18820000
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Repurposing of mTOR Complex Inhibitors Attenuates MCL-1 and Sensitizes to PARP Inhibition.
    Mattoo AR; Joun A; Jessup JM
    Mol Cancer Res; 2019 Jan; 17(1):42-53. PubMed ID: 30201826
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of base excision repair potentiates iododeoxyuridine-induced cytotoxicity and radiosensitization.
    Taverna P; Hwang HS; Schupp JE; Radivoyevitch T; Session NN; Reddy G; Zarling DA; Kinsella TJ
    Cancer Res; 2003 Feb; 63(4):838-46. PubMed ID: 12591735
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Natural product β-thujaplicin inhibits homologous recombination repair and sensitizes cancer cells to radiation therapy.
    Zhang L; Peng Y; Uray IP; Shen J; Wang L; Peng X; Brown PH; Tu W; Peng G
    DNA Repair (Amst); 2017 Dec; 60():89-101. PubMed ID: 29112893
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors.
    Goglia AG; Delsite R; Luz AN; Shahbazian D; Salem AF; Sundaram RK; Chiaravalli J; Hendrikx PJ; Wilshire JA; Jasin M; Kluger HM; Glickman JF; Powell SN; Bindra RS
    Mol Cancer Ther; 2015 Feb; 14(2):326-42. PubMed ID: 25512618
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand Breaks.
    Soni A; Li F; Wang Y; Grabos M; Krieger LM; Chaudhary S; Hasan MSM; Ahmed M; Coleman CN; Teicher BA; Piekarz RL; Wang D; Iliakis GE
    Mol Cancer Ther; 2018 Oct; 17(10):2206-2216. PubMed ID: 29970481
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhancement of radiation response by roscovitine in human breast carcinoma in vitro and in vivo.
    Maggiorella L; Deutsch E; Frascogna V; Chavaudra N; Jeanson L; Milliat F; Eschwege F; Bourhis J
    Cancer Res; 2003 May; 63(10):2513-7. PubMed ID: 12750274
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.