BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

407 related articles for article (PubMed ID: 26124639)

  • 1. Therapeutic effects of C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO-Me; bardoxolone methyl) on radiation-induced lung inflammation and fibrosis in mice.
    Wang YY; Zhang CY; Ma YQ; He ZX; Zhe H; Zhou SF
    Drug Des Devel Ther; 2015; 9():3163-78. PubMed ID: 26124639
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The triterpenoid CDDO-Me inhibits bleomycin-induced lung inflammation and fibrosis.
    Kulkarni AA; Thatcher TH; Hsiao HM; Olsen KC; Kottmann RM; Morrissette J; Wright TW; Phipps RP; Sime PJ
    PLoS One; 2013; 8(5):e63798. PubMed ID: 23741300
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.
    Tran TA; McCoy MK; Sporn MB; Tansey MG
    J Neuroinflammation; 2008 May; 5():14. PubMed ID: 18474101
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells.
    Wang YY; Yang YX; Zhao R; Pan ST; Zhe H; He ZX; Duan W; Zhang X; Yang T; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():993-1026. PubMed ID: 25733817
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bardoxolone methyl (CDDO-Me) as a therapeutic agent: an update on its pharmacokinetic and pharmacodynamic properties.
    Wang YY; Yang YX; Zhe H; He ZX; Zhou SF
    Drug Des Devel Ther; 2014; 8():2075-88. PubMed ID: 25364233
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Methyl Ester of 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid Reduces Endometrial Lesions Development by Modulating the NFkB and Nrf2 Pathways.
    Siracusa R; D'Amico R; Cordaro M; Peritore AF; Genovese T; Gugliandolo E; Crupi R; Impellizzeri D; Cuzzocrea S; Fusco R; Di Paola R
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33924360
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic-acid methyl ester has potent anti-diabetic effects in diet-induced diabetic mice and Lepr(db/db) mice.
    Saha PK; Reddy VT; Konopleva M; Andreeff M; Chan L
    J Biol Chem; 2010 Dec; 285(52):40581-92. PubMed ID: 20956520
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
    Hyer ML; Shi R; Krajewska M; Meyer C; Lebedeva IV; Fisher PB; Reed JC
    Cancer Res; 2008 Apr; 68(8):2927-33. PubMed ID: 18413762
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Preclinical evaluation of targeting the Nrf2 pathway by triterpenoids (CDDO-Im and CDDO-Me) for protection from LPS-induced inflammatory response and reactive oxygen species in human peripheral blood mononuclear cells and neutrophils.
    Thimmulappa RK; Fuchs RJ; Malhotra D; Scollick C; Traore K; Bream JH; Trush MA; Liby KT; Sporn MB; Kensler TW; Biswal S
    Antioxid Redox Signal; 2007 Nov; 9(11):1963-70. PubMed ID: 17822364
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.
    Ferguson HE; Kulkarni A; Lehmann GM; Garcia-Bates TM; Thatcher TH; Huxlin KR; Phipps RP; Sime PJ
    Am J Respir Cell Mol Biol; 2009 Dec; 41(6):722-30. PubMed ID: 19286977
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.
    Nagaraj S; Youn JI; Weber H; Iclozan C; Lu L; Cotter MJ; Meyer C; Becerra CR; Fishman M; Antonia S; Sporn MB; Liby KT; Rawal B; Lee JH; Gabrilovich DI
    Clin Cancer Res; 2010 Mar; 16(6):1812-23. PubMed ID: 20215551
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The synthetic oleanane triterpenoid, CDDO-methyl ester, is a potent antiangiogenic agent.
    Vannini N; Lorusso G; Cammarota R; Barberis M; Noonan DM; Sporn MB; Albini A
    Mol Cancer Ther; 2007 Dec; 6(12 Pt 1):3139-46. PubMed ID: 18065492
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The protective effect of CDDO-Me on lipopolysaccharide-induced acute lung injury in mice.
    Chen T; Mou Y; Tan J; Wei L; Qiao Y; Wei T; Xiang P; Peng S; Zhang Y; Huang Z; Ji H
    Int Immunopharmacol; 2015 Mar; 25(1):55-64. PubMed ID: 25614226
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pirfenidone protects against paraquat-induced lung injury and fibrosis in mice by modulation of inflammation, oxidative stress, and gene expression.
    Pourgholamhossein F; Rasooli R; Pournamdari M; Pourgholi L; Samareh-Fekri M; Ghazi-Khansari M; Iranpour M; Poursalehi HR; Heidari MR; Mandegary A
    Food Chem Toxicol; 2018 Feb; 112():39-46. PubMed ID: 29273418
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling.
    Ling X; Konopleva M; Zeng Z; Ruvolo V; Stephens LC; Schober W; McQueen T; Dietrich M; Madden TL; Andreeff M
    Cancer Res; 2007 May; 67(9):4210-8. PubMed ID: 17483332
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
    Shishodia S; Sethi G; Konopleva M; Andreeff M; Aggarwal BB
    Clin Cancer Res; 2006 Mar; 12(6):1828-38. PubMed ID: 16551868
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and Anticancer Activity of CDDO and CDDO-Me, Two Derivatives of Natural Triterpenoids.
    Borella R; Forti L; Gibellini L; De Gaetano A; De Biasi S; Nasi M; Cossarizza A; Pinti M
    Molecules; 2019 Nov; 24(22):. PubMed ID: 31766211
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combination Therapy with Pirfenidone plus Prednisolone Ameliorates Paraquat-Induced Pulmonary Fibrosis.
    Rasooli R; Pourgholamhosein F; Kamali Y; Nabipour F; Mandegary A
    Inflammation; 2018 Feb; 41(1):134-142. PubMed ID: 28921394
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses.
    Wei J; Zhu H; Komura K; Lord G; Tomcik M; Wang W; Doniparthi S; Tamaki Z; Hinchcliff M; Distler JH; Varga J
    Ann Rheum Dis; 2014 Feb; 73(2):446-54. PubMed ID: 23515440
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice.
    Zhu Y; Liu Y; Zhou W; Xiang R; Jiang L; Huang K; Xiao Y; Guo Z; Gao J
    Respir Res; 2010 Mar; 11(1):34. PubMed ID: 20302663
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.