BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 26136493)

  • 1. Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation.
    Gong Y; Ma Y; Sinyuk M; Loganathan S; Thompson RC; Sarkaria JN; Chen W; Lathia JD; Mobley BC; Clark SW; Wang J
    Neuro Oncol; 2016 Jan; 18(1):48-57. PubMed ID: 26136493
    [TBL] [Abstract][Full Text] [Related]  

  • 2. InsR/IGF1R Pathway Mediates Resistance to EGFR Inhibitors in Glioblastoma.
    Ma Y; Tang N; Thompson RC; Mobley BC; Clark SW; Sarkaria JN; Wang J
    Clin Cancer Res; 2016 Apr; 22(7):1767-76. PubMed ID: 26561558
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Classifying the adverse mitogenic mode of action of insulin analogues using a novel mechanism-based genetically engineered human breast cancer cell panel.
    ter Braak B; Siezen CL; Kannegieter N; Koedoot E; van de Water B; van der Laan JW
    Arch Toxicol; 2014 Apr; 88(4):953-66. PubMed ID: 24464500
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Controlled dimerization of insulin-like growth factor-1 and insulin receptors reveals shared and distinct activities of holo and hybrid receptors.
    Chen J; Nagle AM; Wang YF; Boone DN; Lee AV
    J Biol Chem; 2018 Mar; 293(10):3700-3709. PubMed ID: 29330302
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting Insulin Receptor in Breast Cancer Using Small Engineered Protein Scaffolds.
    Chan JY; Hackel BJ; Yee D
    Mol Cancer Ther; 2017 Jul; 16(7):1324-1334. PubMed ID: 28468775
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of E-cadherin Enhances IGF1-IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR Inhibitors.
    Nagle AM; Levine KM; Tasdemir N; Scott JA; Burlbaugh K; Kehm J; Katz TA; Boone DN; Jacobsen BM; Atkinson JM; Oesterreich S; Lee AV
    Clin Cancer Res; 2018 Oct; 24(20):5165-5177. PubMed ID: 29941485
    [No Abstract]   [Full Text] [Related]  

  • 7. Disruption of insulin receptor function inhibits proliferation in endocrine-resistant breast cancer cells.
    Chan JY; LaPara K; Yee D
    Oncogene; 2016 Aug; 35(32):4235-43. PubMed ID: 26876199
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Both IGF1R and INSR Knockdown Exert Antitumorigenic Effects in Prostate Cancer In Vitro and In Vivo.
    Ofer P; Heidegger I; Eder IE; Schöpf B; Neuwirt H; Geley S; Klocker H; Massoner P
    Mol Endocrinol; 2015 Dec; 29(12):1694-707. PubMed ID: 26452103
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting the Oncogenic Transcriptional Regulator MYB in Adenoid Cystic Carcinoma by Inhibition of IGF1R/AKT Signaling.
    Andersson MK; Afshari MK; Andrén Y; Wick MJ; Stenman G
    J Natl Cancer Inst; 2017 Sep; 109(9):. PubMed ID: 28954282
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Up-regulation of INSR/IGF1R by C-myc promotes TSCC tumorigenesis and metastasis through the NF-κB pathway.
    Sun J; Lu Z; Deng Y; Wang W; He Q; Yan W; Wang A
    Biochim Biophys Acta Mol Basis Dis; 2018 May; 1864(5 Pt A):1873-1882. PubMed ID: 29518496
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hyperactivated Insulin Signaling Cascade in Human Glioblastoma Cells.
    Pei Z; Lee KC; Khan A; Wang HY
    Crit Rev Oncog; 2019; 24(3):243-250. PubMed ID: 32422022
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential expression and signaling activation of insulin receptor isoforms A and B: A link between breast cancer and diabetes.
    Kalla Singh S; Brito C; Tan QW; De León M; De León D
    Growth Factors; 2011 Dec; 29(6):278-89. PubMed ID: 21913804
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis.
    Heidegger I; Kern J; Ofer P; Klocker H; Massoner P
    Oncotarget; 2014 May; 5(9):2723-35. PubMed ID: 24809298
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Efficacy of ganitumab (AMG 479), alone and in combination with rapamycin, in Ewing's and osteogenic sarcoma models.
    Beltran PJ; Chung YA; Moody G; Mitchell P; Cajulis E; Vonderfecht S; Kendall R; Radinsky R; Calzone FJ
    J Pharmacol Exp Ther; 2011 Jun; 337(3):644-54. PubMed ID: 21385891
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential Effects of Insulin and IGF1 Receptors on ERK and AKT Subcellular Distribution in Breast Cancer Cells.
    Sarfstein R; Nagaraj K; LeRoith D; Werner H
    Cells; 2019 Nov; 8(12):. PubMed ID: 31771180
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ridaforolimus (MK-8669) synergizes with Dalotuzumab (MK-0646) in hormone-sensitive breast cancer.
    Becker MA; Hou X; Tienchaianada P; Haines BB; Harrington SC; Weroha SJ; Sathyanarayanan S; Haluska P
    BMC Cancer; 2016 Oct; 16(1):814. PubMed ID: 27765027
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma.
    Loganathan SN; Tang N; Fleming JT; Ma Y; Guo Y; Borinstein SC; Chiang C; Wang J
    Oncotarget; 2016 Jul; 7(28):43504-43517. PubMed ID: 27259270
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CRNDE, a long non-coding RNA responsive to insulin/IGF signaling, regulates genes involved in central metabolism.
    Ellis BC; Graham LD; Molloy PL
    Biochim Biophys Acta; 2014 Feb; 1843(2):372-86. PubMed ID: 24184209
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells.
    Erdem C; Lee AV; Taylor DL; Lezon TR
    PLoS Comput Biol; 2021 Jun; 17(6):e1009125. PubMed ID: 34191793
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combined and individual tumor-specific expression of insulin-like growth factor-I receptor, insulin receptor and phospho-insulin-like growth factor-I receptor/insulin receptor in primary breast cancer: Implications for prognosis in different treatment groups.
    Björner S; Rosendahl AH; Simonsson M; Markkula A; Jirström K; Borgquist S; Rose C; Ingvar C; Jernström H
    Oncotarget; 2017 Feb; 8(6):9093-9107. PubMed ID: 28030849
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.