278 related articles for article (PubMed ID: 26138282)
1. Microsecond simulations of mdm2 and its complex with p53 yield insight into force field accuracy and conformational dynamics.
Pantelopulos GA; Mukherjee S; Voelz VA
Proteins; 2015 Sep; 83(9):1665-76. PubMed ID: 26138282
[TBL] [Abstract][Full Text] [Related]
2. Conformational changes of the p53-binding cleft of MDM2 revealed by molecular dynamics simulations.
Espinoza-Fonseca LM; Trujillo-Ferrara JG
Biopolymers; 2006 Nov; 83(4):365-73. PubMed ID: 16817233
[TBL] [Abstract][Full Text] [Related]
3. Quantitative lid dynamics of MDM2 reveals differential ligand binding modes of the p53-binding cleft.
Showalter SA; Bruschweiler-Li L; Johnson E; Zhang F; Brüschweiler R
J Am Chem Soc; 2008 May; 130(20):6472-8. PubMed ID: 18435534
[TBL] [Abstract][Full Text] [Related]
4. Simulating molecular mechanisms of the MDM2-mediated regulatory interactions: a conformational selection model of the MDM2 lid dynamics.
Verkhivker GM
PLoS One; 2012; 7(7):e40897. PubMed ID: 22815859
[TBL] [Abstract][Full Text] [Related]
5. Effects of force fields on the conformational and dynamic properties of amyloid β(1-40) dimer explored by replica exchange molecular dynamics simulations.
Watts CR; Gregory A; Frisbie C; Lovas S
Proteins; 2018 Mar; 86(3):279-300. PubMed ID: 29235155
[TBL] [Abstract][Full Text] [Related]
6. Binding induced folding in p53-MDM2 complex.
Chen HF; Luo R
J Am Chem Soc; 2007 Mar; 129(10):2930-7. PubMed ID: 17302414
[TBL] [Abstract][Full Text] [Related]
7. Markov models of the apo-MDM2 lid region reveal diffuse yet two-state binding dynamics and receptor poses for computational docking.
Mukherjee S; Pantelopulos GA; Voelz VA
Sci Rep; 2016 Aug; 6():31631. PubMed ID: 27538695
[TBL] [Abstract][Full Text] [Related]
8. Characterizing the conformational landscape of MDM2-binding p53 peptides using Molecular Dynamics simulations.
Yadahalli S; Li J; Lane DP; Gosavi S; Verma CS
Sci Rep; 2017 Nov; 7(1):15600. PubMed ID: 29142290
[TBL] [Abstract][Full Text] [Related]
9. Characterizing the Free-Energy Landscape of MDM2 Protein-Ligand Interactions by Steered Molecular Dynamics Simulations.
Hu G; Xu S; Wang J
Chem Biol Drug Des; 2015 Dec; 86(6):1351-9. PubMed ID: 26032728
[TBL] [Abstract][Full Text] [Related]
10. Targeting the conformational transitions of MDM2 and MDMX: insights into key residues affecting p53 recognition.
Carotti A; Macchiarulo A; Giacchè N; Pellicciari R
Proteins; 2009 Nov; 77(3):524-35. PubMed ID: 19507240
[TBL] [Abstract][Full Text] [Related]
11. A computational analysis of binding modes and conformation changes of MDM2 induced by p53 and inhibitor bindings.
Chen J; Wang J; Zhu W; Li G
J Comput Aided Mol Des; 2013 Nov; 27(11):965-74. PubMed ID: 24264557
[TBL] [Abstract][Full Text] [Related]
12. Direct observations of conformational distributions of intrinsically disordered p53 peptides using UV Raman and explicit solvent simulations.
Xiong K; Zwier MC; Myshakina NS; Burger VM; Asher SA; Chong LT
J Phys Chem A; 2011 Sep; 115(34):9520-7. PubMed ID: 21528875
[TBL] [Abstract][Full Text] [Related]
13. Protein-peptide molecular docking with large-scale conformational changes: the p53-MDM2 interaction.
Ciemny MP; Debinski A; Paczkowska M; Kolinski A; Kurcinski M; Kmiecik S
Sci Rep; 2016 Dec; 6():37532. PubMed ID: 27905468
[TBL] [Abstract][Full Text] [Related]
14. Modulation of p53 binding to MDM2: computational studies reveal important roles of Tyr100.
Dastidar SG; Lane DP; Verma CS
BMC Bioinformatics; 2009 Dec; 10 Suppl 15(Suppl 15):S6. PubMed ID: 19958516
[TBL] [Abstract][Full Text] [Related]
15. Dissociation Process of a MDM2/p53 Complex Investigated by Parallel Cascade Selection Molecular Dynamics and the Markov State Model.
Tran DP; Kitao A
J Phys Chem B; 2019 Mar; 123(11):2469-2478. PubMed ID: 30645121
[TBL] [Abstract][Full Text] [Related]
16. Elucidation of Ligand-Dependent Modulation of Disorder-Order Transitions in the Oncoprotein MDM2.
Bueren-Calabuig JA; Michel J
PLoS Comput Biol; 2015 Jun; 11(6):e1004282. PubMed ID: 26046940
[TBL] [Abstract][Full Text] [Related]
17. Multiple peptide conformations give rise to similar binding affinities: molecular simulations of p53-MDM2.
Dastidar SG; Lane DP; Verma CS
J Am Chem Soc; 2008 Oct; 130(41):13514-5. PubMed ID: 18800837
[TBL] [Abstract][Full Text] [Related]
18. Co-operative intra-protein structural response due to protein-protein complexation revealed through thermodynamic quantification: study of MDM2-p53 binding.
Samanta S; Mukherjee S
J Comput Aided Mol Des; 2017 Oct; 31(10):891-903. PubMed ID: 28871352
[TBL] [Abstract][Full Text] [Related]
19. Molecular dynamics simulations studies and free energy analysis on inhibitors of MDM2-p53 interaction.
Niu RJ; Zheng QC; Zhang JL; Zhang HX
J Mol Graph Model; 2013 Nov; 46():132-9. PubMed ID: 24211465
[TBL] [Abstract][Full Text] [Related]
20. Comparison of Secondary Structure Formation Using 10 Different Force Fields in Microsecond Molecular Dynamics Simulations.
Cino EA; Choy WY; Karttunen M
J Chem Theory Comput; 2012 Aug; 8(8):2725-2740. PubMed ID: 22904695
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]