These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 26139848)

  • 1. Label-free Quantitative Proteomics of Mouse Cerebrospinal Fluid Detects β-Site APP Cleaving Enzyme (BACE1) Protease Substrates In Vivo.
    Dislich B; Wohlrab F; Bachhuber T; Müller SA; Kuhn PH; Hogl S; Meyer-Luehmann M; Lichtenthaler SF
    Mol Cell Proteomics; 2015 Oct; 14(10):2550-63. PubMed ID: 26139848
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.
    Rudan Njavro J; Klotz J; Dislich B; Wanngren J; Shmueli MD; Herber J; Kuhn PH; Kumar R; Koeglsperger T; Conrad M; Wurst W; Feederle R; Vlachos A; Michalakis S; Jedlicka P; Müller SA; Lichtenthaler SF
    FASEB J; 2020 Feb; 34(2):2465-2482. PubMed ID: 31908000
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.
    Pigoni M; Wanngren J; Kuhn PH; Munro KM; Gunnersen JM; Takeshima H; Feederle R; Voytyuk I; De Strooper B; Levasseur MD; Hrupka BJ; Müller SA; Lichtenthaler SF
    Mol Neurodegener; 2016 Oct; 11(1):67. PubMed ID: 27716410
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Label-free quantitative analysis of the membrane proteome of Bace1 protease knock-out zebrafish brains.
    Hogl S; van Bebber F; Dislich B; Kuhn PH; Haass C; Schmid B; Lichtenthaler SF
    Proteomics; 2013 May; 13(9):1519-27. PubMed ID: 23457027
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease.
    Kizuka Y; Kitazume S; Fujinawa R; Saito T; Iwata N; Saido TC; Nakano M; Yamaguchi Y; Hashimoto Y; Staufenbiel M; Hatsuta H; Murayama S; Manya H; Endo T; Taniguchi N
    EMBO Mol Med; 2015 Feb; 7(2):175-89. PubMed ID: 25592972
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome.
    Herber J; Njavro J; Feederle R; Schepers U; Müller UC; Bräse S; Müller SA; Lichtenthaler SF
    Mol Cell Proteomics; 2018 Aug; 17(8):1487-1501. PubMed ID: 29716987
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Associations of CSF BACE1 with amyloid pathology, neurodegeneration, and cognition in Alzheimer's disease.
    Gao F; Zhang M; Wang Q; Ni M; Liu C; Deng K; Xie Q; Wang S; Shi J; Shen Y;
    Acta Neuropathol; 2024 Jun; 147(1):97. PubMed ID: 38856925
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
    Kim W; Ma L; Lomoio S; Willen R; Lombardo S; Dong J; Haydon PG; Tesco G
    Mol Neurodegener; 2018 Feb; 13(1):6. PubMed ID: 29391027
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functions of the Alzheimer's Disease Protease BACE1 at the Synapse in the Central Nervous System.
    Munro KM; Nash A; Pigoni M; Lichtenthaler SF; Gunnersen JM
    J Mol Neurosci; 2016 Nov; 60(3):305-315. PubMed ID: 27456313
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of Cerebrospinal Fluid BACE1 Species.
    Lopez-Font I; Boix CP; Zetterberg H; Blennow K; Sáez-Valero J
    Mol Neurobiol; 2019 Dec; 56(12):8603-8616. PubMed ID: 31290061
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cerebrospinal fluid BACE1 activity and markers of amyloid precursor protein metabolism and axonal degeneration in Alzheimer's disease.
    Perneczky R; Alexopoulos P;
    Alzheimers Dement; 2014 Oct; 10(5 Suppl):S425-S429.e1. PubMed ID: 24239250
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BACE1 Dynamics Upon Inhibition with a BACE Inhibitor and Correlation to Downstream Alzheimer's Disease Markers in Elderly Healthy Participants.
    Timmers M; Barão S; Van Broeck B; Tesseur I; Slemmon J; De Waepenaert K; Bogert J; Shaw LM; Engelborghs S; Moechars D; Mercken M; Van Nueten L; Tritsmans L; de Strooper B; Streffer JR
    J Alzheimers Dis; 2017; 56(4):1437-1449. PubMed ID: 28157093
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BACE1 and Other Alzheimer's-Related Biomarkers in Cerebrospinal Fluid and Plasma Distinguish Alzheimer's Disease Patients from Cognitively-Impaired Neurosyphilis Patients.
    Zhang M; Zhong X; Shi H; Vanmechelen E; De Vos A; Liu S; Chen B; Mai N; Peng Q; Chen X; Wu Z; Hou L; Zhou H; Ouyang C; Zhang W; Liang W; Dai C; Ning Y
    J Alzheimers Dis; 2020; 77(1):313-322. PubMed ID: 32804135
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons.
    Kuhn PH; Koroniak K; Hogl S; Colombo A; Zeitschel U; Willem M; Volbracht C; Schepers U; Imhof A; Hoffmeister A; Haass C; Roßner S; Bräse S; Lichtenthaler SF
    EMBO J; 2012 Jun; 31(14):3157-68. PubMed ID: 22728825
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An optimized quantitative proteomics method establishes the cell type-resolved mouse brain secretome.
    Tüshaus J; Müller SA; Kataka ES; Zaucha J; Sebastian Monasor L; Su M; Güner G; Jocher G; Tahirovic S; Frishman D; Simons M; Lichtenthaler SF
    EMBO J; 2020 Oct; 39(20):e105693. PubMed ID: 32954517
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BACE1 levels correlate with phospho-tau levels in human cerebrospinal fluid.
    Barao S; Zhou L; Adamczuk K; Vanhoutvin T; van Leuven F; Demedts D; Vijverman AC; Bossuyt X; Vandenberghe R; De Strooper B
    Curr Alzheimer Res; 2013 Sep; 10(7):671-8. PubMed ID: 23566348
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
    Sankaranarayanan S; Price EA; Wu G; Crouthamel MC; Shi XP; Tugusheva K; Tyler KX; Kahana J; Ellis J; Jin L; Steele T; Stachel S; Coburn C; Simon AJ
    J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464
    [TBL] [Abstract][Full Text] [Related]  

  • 19. β-Site amyloid precursor protein-cleaving enzyme 1 activity is related to cerebrospinal fluid concentrations of sortilin-related receptor with A-type repeats, soluble amyloid precursor protein, and tau.
    Tsolakidou A; Alexopoulos P; Guo LH; Grimmer T; Westerteicher C; Kratzer M; Jiang M; Bujo H; Roselli F; Leante MR; Livrea P; Kurz A; Perneczky R
    Alzheimers Dement; 2013 Jul; 9(4):386-91. PubMed ID: 23127467
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel mutations introduced at the beta-site of amyloid beta protein precursor enhance the production of amyloid beta peptide by BACE1 in vitro and in cells.
    Shi XP; Tugusheva K; Bruce JE; Lucka A; Chen-Dodson E; Hu B; Wu GX; Price E; Register RB; Lineberger J; Miller R; Tang MJ; Espeseth A; Kahana J; Wolfe A; Crouthamel MC; Sankaranarayanan S; Simon A; Chen L; Lai MT; Pietrak B; DiMuzio J; Li Y; Xu M; Huang Q; Garsky V; Sardana MK; Hazuda DJ
    J Alzheimers Dis; 2005 Apr; 7(2):139-48; discussion 173-80. PubMed ID: 15851852
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.