BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 26141910)

  • 1. Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study.
    Romagnoli R; Baraldi PG; Lopez-Cara C; Cruz-Lopez O; Moorman AR; Massink A; IJzerman AP; Vincenzi F; Borea PA; Varani K
    Eur J Med Chem; 2015 Aug; 101():185-204. PubMed ID: 26141910
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of novel allosteric enhancers of the A1 adenosine receptor based on 2-amino-3-(4'-chlorobenzoyl)-4-substituted-5-arylethynyl thiophene.
    Romagnoli R; Baraldi PG; IJzerman AP; Massink A; Cruz-Lopez O; Lopez-Cara LC; Saponaro G; Preti D; Aghazadeh Tabrizi M; Baraldi S; Moorman AR; Vincenzi F; Borea PA; Varani K
    J Med Chem; 2014 Sep; 57(18):7673-86. PubMed ID: 25181013
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological effects of novel 2-amino-3-(4-chlorobenzoyl)-4-substituted thiophenes as allosteric enhancers of the A1 adenosine receptor.
    Romagnoli R; Baraldi PG; Carrion MD; Lopez Cara C; Kimatrai Salvador M; Preti D; Aghazadeh Tabrizi M; Moorman AR; Vincenzi F; Borea PA; Varani K
    Eur J Med Chem; 2013 Sep; 67():409-27. PubMed ID: 23911855
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5-substituted thiophene derivatives as allosteric enhancers of the A₁ adenosine receptor.
    Romagnoli R; Baraldi PG; Carrion MD; Cruz-Lopez O; Cara CL; Saponaro G; Preti D; Tabrizi MA; Baraldi S; Moorman AR; Vincenzi F; Borea PA; Varani K
    Bioorg Med Chem; 2014 Jan; 22(1):148-66. PubMed ID: 24332652
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4-arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor.
    Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Salvador MK; Preti D; Tabrizi MA; Moorman AR; Vincenzi F; Borea PA; Varani K
    J Med Chem; 2012 Sep; 55(17):7719-35. PubMed ID: 22889387
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and characterization of novel 2-amino-3-benzoylthiophene derivatives as biased allosteric agonists and modulators of the adenosine A(1) receptor.
    Valant C; Aurelio L; Devine SM; Ashton TD; White JM; Sexton PM; Christopoulos A; Scammells PJ
    J Med Chem; 2012 Mar; 55(5):2367-75. PubMed ID: 22315963
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1-yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A₁ adenosine receptor.
    Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Salvador MK; Preti D; Tabrizi MA; Shryock JC; Moorman AR; Vincenzi F; Varani K; Borea PA
    Bioorg Med Chem; 2012 Jan; 20(2):996-1007. PubMed ID: 22182575
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N-(substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor.
    Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Iaconinoto MA; Preti D; Shryock JC; Moorman AR; Vincenzi F; Varani K; Andrea Borea P
    J Med Chem; 2008 Sep; 51(18):5875-9. PubMed ID: 18729349
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Current status of A1 adenosine receptor allosteric enhancers.
    Romagnoli R; Baraldi PG; Moorman AR; Borea PA; Varani K
    Future Med Chem; 2015; 7(10):1247-59. PubMed ID: 26144263
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The synthesis and biological evaluation of 2-amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophenes as allosteric modulators of the A1 adenosine receptor.
    Aurelio L; Christopoulos A; Flynn BL; Scammells PJ; Sexton PM; Valant C
    Bioorg Med Chem Lett; 2011 Jun; 21(12):3704-7. PubMed ID: 21612922
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of 2-amino-3-heteroaroylthiophenes and evaluation of their activity as potential allosteric enhancers at the human A1 receptor.
    Baraldi PG; Pavani MG; Shryock JC; Moorman AR; Iannotta V; Borea PA; Romagnoli R
    Eur J Med Chem; 2004 Oct; 39(10):855-65. PubMed ID: 15464619
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers.
    Nikolakopoulos G; Figler H; Linden J; Scammells PJ
    Bioorg Med Chem; 2006 Apr; 14(7):2358-65. PubMed ID: 16314104
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 2-aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonists.
    Ferguson GN; Valant C; Horne J; Figler H; Flynn BL; Linden J; Chalmers DK; Sexton PM; Christopoulos A; Scammells PJ
    J Med Chem; 2008 Oct; 51(19):6165-72. PubMed ID: 18771255
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological characterization of [3H] (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-(4-chlorophenyl)-methanone, the first radiolabelled adenosine A1 allosteric enhancer.
    Baraldi PG; Pavani MG; Leung E; Moorman AR; Varani K; Vincenzi F; Borea PA; Romagnoli R
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1402-4. PubMed ID: 16321527
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptor.
    Baraldi PG; Romagnoli R; Pavani MG; Nuñez Mdel C; Tabrizi MA; Shryock JC; Leung E; Moorman AR; Uluoglu C; Iannotta V; Merighi S; Borea PA
    J Med Chem; 2003 Feb; 46(5):794-809. PubMed ID: 12593659
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel Irreversible Agonists Acting at the A
    Jörg M; Glukhova A; Abdul-Ridha A; Vecchio EA; Nguyen AT; Sexton PM; White PJ; May LT; Christopoulos A; Scammells PJ
    J Med Chem; 2016 Dec; 59(24):11182-11194. PubMed ID: 27958734
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The allosteric enhancer PD81,723 increases chimaeric A1/A2A adenosine receptor coupling with Gs.
    Bhattacharya S; Youkey RL; Ghartey K; Leonard M; Linden J; Tucker AL
    Biochem J; 2006 May; 396(1):139-46. PubMed ID: 16390330
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Microwave-assisted synthesis of thieno[2,3-c]pyridine derivatives as a new series of allosteric enhancers at the adenosine A(1) receptor.
    Romagnoli R; Baraldi PG; Moorman AR; Iaconinoto MA; Carrion MD; Cara CL; Tabrizi MA; Preti D; Fruttarolo F; Baker SP; Varani K; Borea PA
    Bioorg Med Chem Lett; 2006 Nov; 16(21):5530-3. PubMed ID: 16931014
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-kinetics relationships of Capadenoson derivatives as adenosine A1 receptor agonists.
    Louvel J; Guo D; Soethoudt M; Mocking TA; Lenselink EB; Mulder-Krieger T; Heitman LH; IJzerman AP
    Eur J Med Chem; 2015 Aug; 101():681-91. PubMed ID: 26210506
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Structure-Activity Relationship Study of Bitopic N
    Aurelio L; Baltos JA; Ford L; Nguyen ATN; Jörg M; Devine SM; Valant C; White PJ; Christopoulos A; May LT; Scammells PJ
    J Med Chem; 2018 Mar; 61(5):2087-2103. PubMed ID: 29446948
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.