BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

410 related articles for article (PubMed ID: 26145171)

  • 1. Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry.
    Zhao W; Vaithiyalingam S; San Filippo J; Maranon DG; Jimenez-Sainz J; Fontenay GV; Kwon Y; Leung SG; Lu L; Jensen RB; Chazin WJ; Wiese C; Sung P
    Mol Cell; 2015 Jul; 59(2):176-87. PubMed ID: 26145171
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DSS1 and ssDNA regulate oligomerization of BRCA2.
    Le HP; Ma X; Vaquero J; Brinkmeyer M; Guo F; Heyer WD; Liu J
    Nucleic Acids Res; 2020 Aug; 48(14):7818-7833. PubMed ID: 32609828
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BRCA2 chaperones RAD51 to single molecules of RPA-coated ssDNA.
    Bell JC; Dombrowski CC; Plank JL; Jensen RB; Kowalczykowski SC
    Proc Natl Acad Sci U S A; 2023 Apr; 120(14):e2221971120. PubMed ID: 36976771
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.
    Siaud N; Barbera MA; Egashira A; Lam I; Christ N; Schlacher K; Xia B; Jasin M
    PLoS Genet; 2011 Dec; 7(12):e1002409. PubMed ID: 22194698
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BRCA2 regulates DMC1-mediated recombination through the BRC repeats.
    Martinez JS; von Nicolai C; Kim T; Ehlén Å; Mazin AV; Kowalczykowski SC; Carreira A
    Proc Natl Acad Sci U S A; 2016 Mar; 113(13):3515-20. PubMed ID: 26976601
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.
    Liu J; Doty T; Gibson B; Heyer WD
    Nat Struct Mol Biol; 2010 Oct; 17(10):1260-2. PubMed ID: 20729859
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation.
    Kwon Y; Rösner H; Zhao W; Selemenakis P; He Z; Kawale AS; Katz JN; Rogers CM; Neal FE; Badamchi Shabestari A; Petrosius V; Singh AK; Joel MZ; Lu L; Holloway SP; Burma S; Mukherjee B; Hromas R; Mazin A; Wiese C; Sørensen CS; Sung P
    Nat Commun; 2023 Jan; 14(1):432. PubMed ID: 36702902
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Purified human BRCA2 stimulates RAD51-mediated recombination.
    Jensen RB; Carreira A; Kowalczykowski SC
    Nature; 2010 Oct; 467(7316):678-83. PubMed ID: 20729832
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells.
    Gudmundsdottir K; Lord CJ; Witt E; Tutt AN; Ashworth A
    EMBO Rep; 2004 Oct; 5(10):989-93. PubMed ID: 15359272
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Approaches to Understanding the Mediator Function of Brh2 in Ustilago maydis.
    Zhou Q; Holloman WK; Kojic M
    Methods Enzymol; 2018; 600():513-525. PubMed ID: 29458772
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination.
    Inano S; Sato K; Katsuki Y; Kobayashi W; Tanaka H; Nakajima K; Nakada S; Miyoshi H; Knies K; Takaori-Kondo A; Schindler D; Ishiai M; Kurumizaka H; Takata M
    Mol Cell; 2017 Jun; 66(5):622-634.e8. PubMed ID: 28575658
    [TBL] [Abstract][Full Text] [Related]  

  • 12. EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/recombination syndromes as checkpoint diseases.
    Cousineau I; Belmaaza A
    Mol Genet Genomics; 2011 Apr; 285(4):325-40. PubMed ID: 21409565
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance.
    Lee M; Shorthouse D; Mahen R; Hall BA; Venkitaraman AR
    Nucleic Acids Res; 2021 Jun; 49(10):5588-5604. PubMed ID: 33978741
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DSS1 allosterically regulates the conformation of the tower domain of BRCA2 that has dsDNA binding specificity for homologous recombination.
    Alagar S; Bahadur RP
    Int J Biol Macromol; 2020 Dec; 165(Pt A):918-929. PubMed ID: 33011260
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
    Yang H; Jeffrey PD; Miller J; Kinnucan E; Sun Y; Thoma NH; Zheng N; Chen PL; Lee WH; Pavletich NP
    Science; 2002 Sep; 297(5588):1837-48. PubMed ID: 12228710
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The β-isoform of BCCIP promotes ADP release from the RAD51 presynaptic filament and enhances homologous DNA pairing.
    Kelso AA; Goodson SD; Watts LE; Ledford LL; Waldvogel SM; Diehl JN; Shah SB; Say AF; White JD; Sehorn MG
    Nucleic Acids Res; 2017 Jan; 45(2):711-725. PubMed ID: 27694622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.
    San Filippo J; Chi P; Sehorn MG; Etchin J; Krejci L; Sung P
    J Biol Chem; 2006 Apr; 281(17):11649-57. PubMed ID: 16513631
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions.
    Saeki H; Siaud N; Christ N; Wiegant WW; van Buul PP; Han M; Zdzienicka MZ; Stark JM; Jasin M
    Proc Natl Acad Sci U S A; 2006 Jun; 103(23):8768-73. PubMed ID: 16731627
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor.
    Shahid T; Soroka J; Kong E; Malivert L; McIlwraith MJ; Pape T; West SC; Zhang X
    Nat Struct Mol Biol; 2014 Nov; 21(11):962-968. PubMed ID: 25282148
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lamin A/C recruits ssDNA protective proteins RPA and RAD51 to stalled replication forks to maintain fork stability.
    Graziano S; Coll-Bonfill N; Teodoro-Castro B; Kuppa S; Jackson J; Shashkova E; Mahajan U; Vindigni A; Antony E; Gonzalo S
    J Biol Chem; 2021 Nov; 297(5):101301. PubMed ID: 34648766
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.