404 related articles for article (PubMed ID: 26147105)
1. The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia.
Pappano WN; Guo J; He Y; Ferguson D; Jagadeeswaran S; Osterling DJ; Gao W; Spence JK; Pliushchev M; Sweis RF; Buchanan FG; Michaelides MR; Shoemaker AR; Tse C; Chiang GG
PLoS One; 2015; 10(7):e0131716. PubMed ID: 26147105
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of the G9a/GLP histone methyltransferase complex modulates anxiety-related behavior in mice.
Wang DY; Kosowan J; Samsom J; Leung L; Zhang KL; Li YX; Xiong Y; Jin J; Petronis A; Oh G; Wong AHC
Acta Pharmacol Sin; 2018 May; 39(5):866-874. PubMed ID: 29417943
[TBL] [Abstract][Full Text] [Related]
3. Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma.
Yokoyama M; Chiba T; Zen Y; Oshima M; Kusakabe Y; Noguchi Y; Yuki K; Koide S; Tara S; Saraya A; Aoyama K; Mimura N; Miyagi S; Inoue M; Wakamatsu T; Saito T; Ogasawara S; Suzuki E; Ooka Y; Tawada A; Otsuka M; Miyazaki M; Yokosuka O; Iwama A
Oncotarget; 2017 Mar; 8(13):21315-21326. PubMed ID: 28423509
[TBL] [Abstract][Full Text] [Related]
4. Discovery of novel histone lysine methyltransferase G9a/GLP (EHMT2/1) inhibitors: Design, synthesis, and structure-activity relationships of 2,4-diamino-6-methylpyrimidines.
Katayama K; Ishii K; Tsuda E; Yotsumoto K; Hiramoto K; Suzuki M; Yasumatsu I; Igarashi W; Torihata M; Ishiyama T; Katagiri T
Bioorg Med Chem Lett; 2020 Oct; 30(20):127475. PubMed ID: 32781218
[TBL] [Abstract][Full Text] [Related]
5. A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.
Vedadi M; Barsyte-Lovejoy D; Liu F; Rival-Gervier S; Allali-Hassani A; Labrie V; Wigle TJ; Dimaggio PA; Wasney GA; Siarheyeva A; Dong A; Tempel W; Wang SC; Chen X; Chau I; Mangano TJ; Huang XP; Simpson CD; Pattenden SG; Norris JL; Kireev DB; Tripathy A; Edwards A; Roth BL; Janzen WP; Garcia BA; Petronis A; Ellis J; Brown PJ; Frye SV; Arrowsmith CH; Jin J
Nat Chem Biol; 2011 Jul; 7(8):566-74. PubMed ID: 21743462
[TBL] [Abstract][Full Text] [Related]
6. De novo methylation of histone H3K23 by the methyltransferases EHMT1/GLP and EHMT2/G9a.
Vinson DA; Stephens KE; O'Meally RN; Bhat S; Dancy BCR; Cole RN; Yegnasubramanian S; Taverna SD
Epigenetics Chromatin; 2022 Nov; 15(1):36. PubMed ID: 36411491
[TBL] [Abstract][Full Text] [Related]
7. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.
Kubicek S; O'Sullivan RJ; August EM; Hickey ER; Zhang Q; Teodoro ML; Rea S; Mechtler K; Kowalski JA; Homon CA; Kelly TA; Jenuwein T
Mol Cell; 2007 Feb; 25(3):473-81. PubMed ID: 17289593
[TBL] [Abstract][Full Text] [Related]
8. Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase.
Xiong Y; Li F; Babault N; Dong A; Zeng H; Wu H; Chen X; Arrowsmith CH; Brown PJ; Liu J; Vedadi M; Jin J
J Med Chem; 2017 Mar; 60(5):1876-1891. PubMed ID: 28135087
[TBL] [Abstract][Full Text] [Related]
9. Discovery of novel small molecule inhibitors of lysine methyltransferase G9a and their mechanism in leukemia cell lines.
Kondengaden SM; Luo LF; Huang K; Zhu M; Zang L; Bataba E; Wang R; Luo C; Wang B; Li KK; Wang PG
Eur J Med Chem; 2016 Oct; 122():382-393. PubMed ID: 27393948
[TBL] [Abstract][Full Text] [Related]
10. The histone methyltransferase G9a: a new therapeutic target in biliary tract cancer.
Mayr C; Helm K; Jakab M; Ritter M; Shrestha R; Makaju R; Wagner A; Pichler M; Beyreis M; Staettner S; Jaeger T; Klieser E; Kiesslich T; Neureiter D
Hum Pathol; 2018 Feb; 72():117-126. PubMed ID: 29133140
[TBL] [Abstract][Full Text] [Related]
11. The lysine methyltransferase Ehmt2/G9a is dispensable for skeletal muscle development and regeneration.
Zhang RH; Judson RN; Liu DY; Kast J; Rossi FM
Skelet Muscle; 2016; 6():22. PubMed ID: 27239264
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II).
Lenstra DC; Al Temimi AHK; Mecinović J
Bioorg Med Chem Lett; 2018 Apr; 28(7):1234-1238. PubMed ID: 29519735
[TBL] [Abstract][Full Text] [Related]
13. Histone Methyltransferase G9a Is Required for Cardiomyocyte Homeostasis and Hypertrophy.
Papait R; Serio S; Pagiatakis C; Rusconi F; Carullo P; Mazzola M; Salvarani N; Miragoli M; Condorelli G
Circulation; 2017 Sep; 136(13):1233-1246. PubMed ID: 28778944
[TBL] [Abstract][Full Text] [Related]
14. Histone Methyltransferases G9a/
Souza BK; Freire NH; Monteiro TS; Herlinger AL; Jaeger M; Dalmolin MGS; de Farias CB; Gregianin L; Brunetto AT; Brunetto AL; Thiele CJ; Roesler R
Int J Mol Sci; 2023 Oct; 24(20):. PubMed ID: 37894922
[TBL] [Abstract][Full Text] [Related]
15. GLP overexpression is associated with poor prognosis in Chronic Lymphocytic Leukemia and its inhibition induces leukemic cell death.
Alves-Silva JC; de Carvalho JL; Rabello DA; Serejo TRT; Rego EM; Neves FAR; Lucena-Araujo AR; Pittella-Silva F; Saldanha-Araujo F
Invest New Drugs; 2018 Oct; 36(5):955-960. PubMed ID: 29855824
[TBL] [Abstract][Full Text] [Related]
16. G9a/GLP histone lysine dimethyltransferase complex activity in the hippocampus and the entorhinal cortex is required for gene activation and silencing during memory consolidation.
Gupta-Agarwal S; Franklin AV; Deramus T; Wheelock M; Davis RL; McMahon LL; Lubin FD
J Neurosci; 2012 Apr; 32(16):5440-53. PubMed ID: 22514307
[TBL] [Abstract][Full Text] [Related]
17. Unexpected Distinct Roles of the Related Histone H3 Lysine 9 Methyltransferases G9a and G9a-Like Protein in Myoblasts.
Battisti V; Pontis J; Boyarchuk E; Fritsch L; Robin P; Ait-Si-Ali S; Joliot V
J Mol Biol; 2016 Jun; 428(11):2329-2343. PubMed ID: 27056598
[TBL] [Abstract][Full Text] [Related]
18. Structure-Based Design and Characterization of the Highly Potent and Selective Covalent Inhibitors Targeting the Lysine Methyltransferases G9a/GLP.
Feng Z; Yang C; Zhang Y; Li H; Fang W; Wang J; Nie Y; Wang CY; Liu Z; Jiang Z; Wang J; Wang Y
J Med Chem; 2023 Jun; 66(12):8086-8102. PubMed ID: 37268593
[TBL] [Abstract][Full Text] [Related]
19. Epigenetics and memory: Emerging role of histone lysine methyltransferase G9a/GLP complex as bidirectional regulator of synaptic plasticity.
Pang KKL; Sharma M; Sajikumar S
Neurobiol Learn Mem; 2019 Mar; 159():1-5. PubMed ID: 30703547
[TBL] [Abstract][Full Text] [Related]
20. Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells.
Deguchi K; Nagamatsu G; Miyachi H; Kato Y; Morita S; Kimura H; Kitano S; Hatada I; Saga Y; Tachibana M; Shinkai Y
Biol Reprod; 2013 Feb; 88(2):36. PubMed ID: 23284137
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
