310 related articles for article (PubMed ID: 26147621)
1. Dichloroacetate, the Pyruvate Dehydrogenase Complex and the Modulation of mESC Pluripotency.
Rodrigues AS; Correia M; Gomes A; Pereira SL; Perestrelo T; Sousa MI; Ramalho-Santos J
PLoS One; 2015; 10(7):e0131663. PubMed ID: 26147621
[TBL] [Abstract][Full Text] [Related]
2. Differentiate or Die: 3-Bromopyruvate and Pluripotency in Mouse Embryonic Stem Cells.
Rodrigues AS; Pereira SL; Correia M; Gomes A; Perestrelo T; Ramalho-Santos J
PLoS One; 2015; 10(8):e0135617. PubMed ID: 26266544
[TBL] [Abstract][Full Text] [Related]
3. Activation of pyruvate dehydrogenase by dichloroacetate has the potential to induce epigenetic remodeling in the heart.
Matsuhashi T; Hishiki T; Zhou H; Ono T; Kaneda R; Iso T; Yamaguchi A; Endo J; Katsumata Y; Atsushi A; Yamamoto T; Shirakawa K; Yan X; Shinmura K; Suematsu M; Fukuda K; Sano M
J Mol Cell Cardiol; 2015 May; 82():116-24. PubMed ID: 25744081
[TBL] [Abstract][Full Text] [Related]
4. Dichloroacetate induces regulatory T-cell differentiation and suppresses Th17-cell differentiation by pyruvate dehydrogenase kinase-independent mechanism.
Makita N; Ishiguro J; Suzuki K; Nara F
J Pharm Pharmacol; 2017 Jan; 69(1):43-51. PubMed ID: 27757958
[TBL] [Abstract][Full Text] [Related]
5. The regulation of pyruvate dehydrogenase activity in rat hippocampal slices: effect of dichloroacetate.
Baudry M; Kessler M; Smith EK; Lynch G
Neurosci Lett; 1982 Jul; 31(1):41-6. PubMed ID: 6289199
[TBL] [Abstract][Full Text] [Related]
6. Expression and regulation of pyruvate dehydrogenase kinase isoforms in the developing rat heart and in adulthood: role of thyroid hormone status and lipid supply.
Sugden MC; Langdown ML; Harris RA; Holness MJ
Biochem J; 2000 Dec; 352 Pt 3(Pt 3):731-8. PubMed ID: 11104680
[TBL] [Abstract][Full Text] [Related]
7. Functional response of the isolated, perfused normoxic heart to pyruvate dehydrogenase activation by dichloroacetate and pyruvate.
Jaimes R; Kuzmiak-Glancy S; Brooks DM; Swift LM; Posnack NG; Kay MW
Pflugers Arch; 2016 Jan; 468(1):131-142. PubMed ID: 26142699
[TBL] [Abstract][Full Text] [Related]
8. Phosphorylation-mediated changes in pyruvate dehydrogenase activity influence pyruvate-supported calcium accumulation by brain mitochondria.
Browning M; Baudry M; Bennett WF; Lynch G
J Neurochem; 1981 Jun; 36(6):1932-40. PubMed ID: 7241145
[TBL] [Abstract][Full Text] [Related]
9. Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage differentiation.
Kumar A; Kant S; Singh SM
Toxicol Appl Pharmacol; 2013 Nov; 273(1):196-208. PubMed ID: 24051182
[TBL] [Abstract][Full Text] [Related]
10. IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
Izquierdo-Garcia JL; Viswanath P; Eriksson P; Cai L; Radoul M; Chaumeil MM; Blough M; Luchman HA; Weiss S; Cairncross JG; Phillips JJ; Pieper RO; Ronen SM
Cancer Res; 2015 Aug; 75(15):2999-3009. PubMed ID: 26045167
[TBL] [Abstract][Full Text] [Related]
11. Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.
Stacpoole PW
J Natl Cancer Inst; 2017 Nov; 109(11):. PubMed ID: 29059435
[TBL] [Abstract][Full Text] [Related]
12. Pyruvate dehydrogenase kinase expression and metabolic changes following dichloroacetate exposure in anoxic human colorectal cancer cells.
Ho N; Coomber BL
Exp Cell Res; 2015 Feb; 331(1):73-81. PubMed ID: 25536473
[TBL] [Abstract][Full Text] [Related]
13. Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines.
Tataranni T; Agriesti F; Pacelli C; Ruggieri V; Laurenzana I; Mazzoccoli C; Sala GD; Panebianco C; Pazienza V; Capitanio N; Piccoli C
Cells; 2019 May; 8(5):. PubMed ID: 31109089
[TBL] [Abstract][Full Text] [Related]
14. Stabilization of the pyruvate dehydrogenase E1alpha subunit by dichloroacetate.
Morten KJ; Caky M; Matthews PM
Neurology; 1998 Nov; 51(5):1331-5. PubMed ID: 9818855
[TBL] [Abstract][Full Text] [Related]
15. PDH activation by dichloroacetate reduces TCA cycle intermediates at rest but not during exercise in humans.
Gibala MJ; Saltin B
Am J Physiol; 1999 Jul; 277(1):E33-8. PubMed ID: 10409125
[TBL] [Abstract][Full Text] [Related]
16. The Effects of Sodium Dichloroacetate on Mitochondrial Dysfunction and Neuronal Death Following Hypoglycemia-Induced Injury.
Kho AR; Choi BY; Lee SH; Hong DK; Jeong JH; Kang BS; Kang DH; Park KH; Park JB; Suh SW
Cells; 2019 May; 8(5):. PubMed ID: 31052436
[TBL] [Abstract][Full Text] [Related]
17. Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis.
Ferrarini MG; Nisimura LM; Girard RMBM; Alencar MB; Fragoso MSI; Araújo-Silva CA; Veiga AA; Abud APR; Nardelli SC; Vommaro RC; Silber AM; France-Sagot M; Ávila AR
mSphere; 2021 Jan; 6(1):. PubMed ID: 33408226
[TBL] [Abstract][Full Text] [Related]
18. Activation of Pyruvate Dehydrogenase by Sodium Dichloroacetate Shifts Metabolic Consumption from Amino Acids to Glucose in IPEC-J2 Cells and Intestinal Bacteria in Pigs.
An R; Tang Z; Li Y; Li T; Xu Q; Zhen J; Huang F; Yang J; Chen C; Wu Z; Li M; Sun J; Zhang X; Chen J; Wu L; Zhao S; Qingyan J; Zhu W; Yin Y; Sun Z
J Agric Food Chem; 2018 Apr; 66(15):3793-3800. PubMed ID: 29471628
[TBL] [Abstract][Full Text] [Related]
19. Regulation of pyruvate dehydrogenase activity and glucose metabolism in post-ischaemic myocardium.
Schöder H; Knight RJ; Kofoed KF; Schelbert HR; Buxton DB
Biochim Biophys Acta; 1998 Feb; 1406(1):62-72. PubMed ID: 9545535
[TBL] [Abstract][Full Text] [Related]
20. Inactivation of the HIF-1α/PDK3 signaling axis drives melanoma toward mitochondrial oxidative metabolism and potentiates the therapeutic activity of pro-oxidants.
Kluza J; Corazao-Rozas P; Touil Y; Jendoubi M; Maire C; Guerreschi P; Jonneaux A; Ballot C; Balayssac S; Valable S; Corroyer-Dulmont A; Bernaudin M; Malet-Martino M; de Lassalle EM; Maboudou P; Formstecher P; Polakowska R; Mortier L; Marchetti P
Cancer Res; 2012 Oct; 72(19):5035-47. PubMed ID: 22865452
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
