BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 26148237)

  • 1. Structural basis of how stress-induced MDMX phosphorylation activates p53.
    Chen X; Gohain N; Zhan C; Lu WY; Pazgier M; Lu W
    Oncogene; 2016 Apr; 35(15):1919-25. PubMed ID: 26148237
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX.
    Pazgier M; Liu M; Zou G; Yuan W; Li C; Li C; Li J; Monbo J; Zella D; Tarasov SG; Lu W
    Proc Natl Acad Sci U S A; 2009 Mar; 106(12):4665-70. PubMed ID: 19255450
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional Interrogation of the N-Terminal Lid of MDMX in p53 Binding via Native Chemical Ligation.
    Chen X; Lu W
    Chem Pharm Bull (Tokyo); 2016; 64(7):1004-8. PubMed ID: 27373663
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Systematic mutational analysis of peptide inhibition of the p53-MDM2/MDMX interactions.
    Li C; Pazgier M; Li C; Yuan W; Liu M; Wei G; Lu WY; Lu W
    J Mol Biol; 2010 Apr; 398(2):200-13. PubMed ID: 20226197
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
    Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
    EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Secondary interaction between MDMX and p53 core domain inhibits p53 DNA binding.
    Wei X; Wu S; Song T; Chen L; Gao M; Borcherds W; Daughdrill GW; Chen J
    Proc Natl Acad Sci U S A; 2016 May; 113(19):E2558-63. PubMed ID: 27114532
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular basis for the inhibition of p53 by Mdmx.
    Popowicz GM; Czarna A; Rothweiler U; Szwagierczak A; Krajewski M; Weber L; Holak TA
    Cell Cycle; 2007 Oct; 6(19):2386-92. PubMed ID: 17938582
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A site-directed mutagenesis study of the MdmX RING domain.
    Egorova O; Mis M; Sheng Y
    Biochem Biophys Res Commun; 2014 May; 447(4):696-701. PubMed ID: 24755078
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.
    Okamoto K; Kashima K; Pereg Y; Ishida M; Yamazaki S; Nota A; Teunisse A; Migliorini D; Kitabayashi I; Marine JC; Prives C; Shiloh Y; Jochemsen AG; Taya Y
    Mol Cell Biol; 2005 Nov; 25(21):9608-20. PubMed ID: 16227609
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain.
    Popowicz GM; Czarna A; Holak TA
    Cell Cycle; 2008 Aug; 7(15):2441-3. PubMed ID: 18677113
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human epidermal growth factor receptor 4 (Her4) Suppresses p53 Protein via Targeting the MDMX-MDM2 Protein Complex: IMPLICATION OF A NOVEL MDMX SER-314 PHOSPHOSITE.
    Gerarduzzi C; de Polo A; Liu XS; El Kharbili M; Little JB; Yuan ZM
    J Biol Chem; 2016 Dec; 291(50):25937-25949. PubMed ID: 27777309
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation.
    Meulmeester E; Pereg Y; Shiloh Y; Jochemsen AG
    Cell Cycle; 2005 Sep; 4(9):1166-70. PubMed ID: 16082221
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of p53: a collaboration between Mdm2 and Mdmx.
    Pei D; Zhang Y; Zheng J
    Oncotarget; 2012 Mar; 3(3):228-35. PubMed ID: 22410433
    [TBL] [Abstract][Full Text] [Related]  

  • 14. AMP-activated protein kinase induces p53 by phosphorylating MDMX and inhibiting its activity.
    He G; Zhang YW; Lee JH; Zeng SX; Wang YV; Luo Z; Dong XC; Viollet B; Wahl GM; Lu H
    Mol Cell Biol; 2014 Jan; 34(2):148-57. PubMed ID: 24190973
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MDM2 promotes ubiquitination and degradation of MDMX.
    Pan Y; Chen J
    Mol Cell Biol; 2003 Aug; 23(15):5113-21. PubMed ID: 12860999
    [TBL] [Abstract][Full Text] [Related]  

  • 16. AXL receptor signalling suppresses p53 in melanoma through stabilization of the MDMX-MDM2 complex.
    de Polo A; Luo Z; Gerarduzzi C; Chen X; Little JB; Yuan ZM
    J Mol Cell Biol; 2017 Apr; 9(2):154-165. PubMed ID: 27927748
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation
    Yang J; Jin A; Han J; Chen X; Zheng J; Zhang Y
    Cancer Res; 2021 Feb; 81(4):898-909. PubMed ID: 33277368
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Abnormal MDMX degradation in tumor cells due to ARF deficiency.
    Li X; Gilkes D; Li B; Cheng Q; Pernazza D; Lawrence H; Lawrence N; Chen J
    Oncogene; 2012 Aug; 31(32):3721-32. PubMed ID: 22120712
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inferring Leading Interactions in the p53/Mdm2/Mdmx Circuit through Live-Cell Imaging and Modeling.
    Heltberg ML; Chen SH; Jiménez A; Jambhekar A; Jensen MH; Lahav G
    Cell Syst; 2019 Dec; 9(6):548-558.e5. PubMed ID: 31812692
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mdmx promotes genomic instability independent of p53 and Mdm2.
    Carrillo AM; Bouska A; Arrate MP; Eischen CM
    Oncogene; 2015 Feb; 34(7):846-56. PubMed ID: 24608433
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.