BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1044 related articles for article (PubMed ID: 26158266)

  • 1. Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells.
    Woo YM; Shin Y; Lee EJ; Lee S; Jeong SH; Kong HK; Park EY; Kim HK; Han J; Chang M; Park JH
    PLoS One; 2015; 10(7):e0132285. PubMed ID: 26158266
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Knockdown of KLF5 suppresses hypoxia-induced resistance to cisplatin in NSCLC cells by regulating HIF-1α-dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway.
    Gong T; Cui L; Wang H; Wang H; Han N
    J Transl Med; 2018 Jun; 16(1):164. PubMed ID: 29898734
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Long Non-Coding RNA (lncRNA) Urothelial Carcinoma-Associated 1 (UCA1) Enhances Tamoxifen Resistance in Breast Cancer Cells via Inhibiting mTOR Signaling Pathway.
    Wu C; Luo J
    Med Sci Monit; 2016 Oct; 22():3860-3867. PubMed ID: 27765938
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.
    deGraffenried LA; Friedrichs WE; Russell DH; Donzis EJ; Middleton AK; Silva JM; Roth RA; Hidalgo M
    Clin Cancer Res; 2004 Dec; 10(23):8059-67. PubMed ID: 15585641
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Curcumin induces cell death and restores tamoxifen sensitivity in the antiestrogen-resistant breast cancer cell lines MCF-7/LCC2 and MCF-7/LCC9.
    Jiang M; Huang O; Zhang X; Xie Z; Shen A; Liu H; Geng M; Shen K
    Molecules; 2013 Jan; 18(1):701-20. PubMed ID: 23299550
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The phenomenon of acquired resistance to metformin in breast cancer cells: The interaction of growth pathways and estrogen receptor signaling.
    Scherbakov AM; Sorokin DV; Tatarskiy VV; Prokhorov NS; Semina SE; Berstein LM; Krasil'nikov MA
    IUBMB Life; 2016 Apr; 68(4):281-92. PubMed ID: 26892736
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Anticancer Effects of γ-Tocotrienol Are Associated with a Suppression in Aerobic Glycolysis.
    Parajuli P; Tiwari RV; Sylvester PW
    Biol Pharm Bull; 2015; 38(9):1352-60. PubMed ID: 26328490
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen.
    Brünner N; Boysen B; Jirus S; Skaar TC; Holst-Hansen C; Lippman J; Frandsen T; Spang-Thomsen M; Fuqua SA; Clarke R
    Cancer Res; 1997 Aug; 57(16):3486-93. PubMed ID: 9270017
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glycometabolic adaptation mediates the insensitivity of drug-resistant K562/ADM leukaemia cells to adriamycin via the AKT-mTOR/c-Myc signalling pathway.
    Zhang X; Ai Z; Chen J; Yi J; Liu Z; Zhao H; Wei H
    Mol Med Rep; 2017 Apr; 15(4):1869-1876. PubMed ID: 28259993
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of the AKT/mTOR and erbB pathways by gefitinib, perifosine and analogs of gonadotropin-releasing hormone I and II to overcome tamoxifen resistance in breast cancer cells.
    Block M; Gründker C; Fister S; Kubin J; Wilkens L; Mueller MD; Hemmerlein B; Emons G; Günthert AR
    Int J Oncol; 2012 Nov; 41(5):1845-54. PubMed ID: 22922893
    [TBL] [Abstract][Full Text] [Related]  

  • 11. INPP4B-mediated tumor resistance is associated with modulation of glucose metabolism via hexokinase 2 regulation in laryngeal cancer cells.
    Min JW; Kim KI; Kim HA; Kim EK; Noh WC; Jeon HB; Cho DH; Oh JS; Park IC; Hwang SG; Kim JS
    Biochem Biophys Res Commun; 2013 Oct; 440(1):137-42. PubMed ID: 24051093
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dual inhibition of PI3K and mTOR mitigates compensatory AKT activation and improves tamoxifen response in breast cancer.
    Chen X; Zhao M; Hao M; Sun X; Wang J; Mao Y; Zu L; Liu J; Shen Y; Wang J; Shen K
    Mol Cancer Res; 2013 Oct; 11(10):1269-78. PubMed ID: 23814023
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway.
    Wang H; Zhao L; Zhu LT; Wang Y; Pan D; Yao J; You QD; Guo QL
    Mol Carcinog; 2014 Feb; 53 Suppl 1():E107-18. PubMed ID: 23761018
    [TBL] [Abstract][Full Text] [Related]  

  • 14. AMPK Activation and Metabolic Reprogramming by Tamoxifen through Estrogen Receptor-Independent Mechanisms Suggests New Uses for This Therapeutic Modality in Cancer Treatment.
    Daurio NA; Tuttle SW; Worth AJ; Song EY; Davis JM; Snyder NW; Blair IA; Koumenis C
    Cancer Res; 2016 Jun; 76(11):3295-306. PubMed ID: 27020861
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Clk1-regulated aerobic glycolysis is involved in glioma chemoresistance.
    Zhang L; Yang H; Zhang W; Liang Z; Huang Q; Xu G; Zhen X; Zheng LT
    J Neurochem; 2017 Aug; 142(4):574-588. PubMed ID: 28581641
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nuclear respiratory factor-1 and bioenergetics in tamoxifen-resistant breast cancer cells.
    Radde BN; Ivanova MM; Mai HX; Alizadeh-Rad N; Piell K; Van Hoose P; Cole MP; Muluhngwi P; Kalbfleisch TS; Rouchka EC; Hill BG; Klinge CM
    Exp Cell Res; 2016 Sep; 347(1):222-231. PubMed ID: 27515002
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ascofuranone suppresses EGF-induced HIF-1α protein synthesis by inhibition of the Akt/mTOR/p70S6K pathway in MDA-MB-231 breast cancer cells.
    Jeong YJ; Cho HJ; Magae J; Lee IK; Park KG; Chang YC
    Toxicol Appl Pharmacol; 2013 Dec; 273(3):542-50. PubMed ID: 24096035
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Wortmannin influences hypoxia-inducible factor-1 alpha expression and glycolysis in esophageal carcinoma cells.
    Zeng L; Zhou HY; Tang NN; Zhang WF; He GJ; Hao B; Feng YD; Zhu H
    World J Gastroenterol; 2016 May; 22(20):4868-80. PubMed ID: 27239113
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting the ROS/PI3K/AKT/HIF-1α/HK2 axis of breast cancer cells: Combined administration of Polydatin and 2-Deoxy-d-glucose.
    Zhang T; Zhu X; Wu H; Jiang K; Zhao G; Shaukat A; Deng G; Qiu C
    J Cell Mol Med; 2019 May; 23(5):3711-3723. PubMed ID: 30920152
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acquisition of epithelial-mesenchymal transition phenotype in the tamoxifen-resistant breast cancer cell: a new role for G protein-coupled estrogen receptor in mediating tamoxifen resistance through cancer-associated fibroblast-derived fibronectin and β1-integrin signaling pathway in tumor cells.
    Yuan J; Liu M; Yang L; Tu G; Zhu Q; Chen M; Cheng H; Luo H; Fu W; Li Z; Yang G
    Breast Cancer Res; 2015 May; 17(1):69. PubMed ID: 25990368
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 53.