BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1038 related articles for article (PubMed ID: 26159692)

  • 1. Regulation of mTORC1 by PI3K signaling.
    Dibble CC; Cantley LC
    Trends Cell Biol; 2015 Sep; 25(9):545-55. PubMed ID: 26159692
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.
    Carroll B; Maetzel D; Maddocks OD; Otten G; Ratcliff M; Smith GR; Dunlop EA; Passos JF; Davies OR; Jaenisch R; Tee AR; Sarkar S; Korolchuk VI
    Elife; 2016 Jan; 5():. PubMed ID: 26742086
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.
    Menon S; Dibble CC; Talbott G; Hoxhaj G; Valvezan AJ; Takahashi H; Cantley LC; Manning BD
    Cell; 2014 Feb; 156(4):771-85. PubMed ID: 24529379
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Amino acid regulation of TOR complex 1.
    Avruch J; Long X; Ortiz-Vega S; Rapley J; Papageorgiou A; Dai N
    Am J Physiol Endocrinol Metab; 2009 Apr; 296(4):E592-602. PubMed ID: 18765678
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Point mutations of the mTOR-RHEB pathway in renal cell carcinoma.
    Ghosh AP; Marshall CB; Coric T; Shim EH; Kirkman R; Ballestas ME; Ikura M; Bjornsti MA; Sudarshan S
    Oncotarget; 2015 Jul; 6(20):17895-910. PubMed ID: 26255626
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mammalian target of rapamycin and tuberous sclerosis complex.
    Wataya-Kaneda M
    J Dermatol Sci; 2015 Aug; 79(2):93-100. PubMed ID: 26051878
    [TBL] [Abstract][Full Text] [Related]  

  • 8. REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling.
    Dennis MD; Coleman CS; Berg A; Jefferson LS; Kimball SR
    Sci Signal; 2014 Jul; 7(335):ra68. PubMed ID: 25056877
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rheb and Rags come together at the lysosome to activate mTORC1.
    Groenewoud MJ; Zwartkruis FJ
    Biochem Soc Trans; 2013 Aug; 41(4):951-5. PubMed ID: 23863162
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
    Dibble CC; Elis W; Menon S; Qin W; Klekota J; Asara JM; Finan PM; Kwiatkowski DJ; Murphy LO; Manning BD
    Mol Cell; 2012 Aug; 47(4):535-46. PubMed ID: 22795129
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Current models of mammalian target of rapamycin complex 1 (mTORC1) activation by growth factors and amino acids.
    Zheng X; Liang Y; He Q; Yao R; Bao W; Bao L; Wang Y; Wang Z
    Int J Mol Sci; 2014 Nov; 15(11):20753-69. PubMed ID: 25402640
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation.
    Dalle Pezze P; Sonntag AG; Thien A; Prentzell MT; Gödel M; Fischer S; Neumann-Haefelin E; Huber TB; Baumeister R; Shanley DP; Thedieck K
    Sci Signal; 2012 Mar; 5(217):ra25. PubMed ID: 22457331
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Key mediators of intracellular amino acids signaling to mTORC1 activation.
    Duan Y; Li F; Tan K; Liu H; Li Y; Liu Y; Kong X; Tang Y; Wu G; Yin Y
    Amino Acids; 2015 May; 47(5):857-67. PubMed ID: 25701492
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation.
    Foster KG; Acosta-Jaquez HA; Romeo Y; Ekim B; Soliman GA; Carriere A; Roux PP; Ballif BA; Fingar DC
    J Biol Chem; 2010 Jan; 285(1):80-94. PubMed ID: 19864431
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress.
    Ozturk DG; Kocak M; Akcay A; Kinoglu K; Kara E; Buyuk Y; Kazan H; Gozuacik D
    Autophagy; 2019 Mar; 15(3):375-390. PubMed ID: 30290719
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Requirement for lysosomal localization of mTOR for its activation differs between leucine and other amino acids.
    Averous J; Lambert-Langlais S; Carraro V; Gourbeyre O; Parry L; B'Chir W; Muranishi Y; Jousse C; Bruhat A; Maurin AC; Proud CG; Fafournoux P
    Cell Signal; 2014 Sep; 26(9):1918-27. PubMed ID: 24793303
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MCRS1 binds and couples Rheb to amino acid-dependent mTORC1 activation.
    Fawal MA; Brandt M; Djouder N
    Dev Cell; 2015 Apr; 33(1):67-81. PubMed ID: 25816988
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fisetin regulates obesity by targeting mTORC1 signaling.
    Jung CH; Kim H; Ahn J; Jeon TI; Lee DH; Ha TY
    J Nutr Biochem; 2013 Aug; 24(8):1547-54. PubMed ID: 23517912
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase.
    Avruch J; Hara K; Lin Y; Liu M; Long X; Ortiz-Vega S; Yonezawa K
    Oncogene; 2006 Oct; 25(48):6361-72. PubMed ID: 17041622
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes.
    Ögmundsdóttir MH; Heublein S; Kazi S; Reynolds B; Visvalingam SM; Shaw MK; Goberdhan DC
    PLoS One; 2012; 7(5):e36616. PubMed ID: 22574197
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 52.