266 related articles for article (PubMed ID: 26161903)
21. Efficient spontaneous site-selective cysteine-mediated toxin attachment within a structural loop of antibodies.
Stadlmayr G; Stracke F; Stadlbauer K; Rybka J; Dickgiesser S; Rasche N; Becker S; Toleikis L; Rüker F; Knopp GW
Biochim Biophys Acta Gen Subj; 2022 Jul; 1866(7):130155. PubMed ID: 35469978
[TBL] [Abstract][Full Text] [Related]
22. Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates.
Nanna AR; Li X; Walseng E; Pedzisa L; Goydel RS; Hymel D; Burke TR; Roush WR; Rader C
Nat Commun; 2017 Oct; 8(1):1112. PubMed ID: 29062027
[TBL] [Abstract][Full Text] [Related]
23. Sortase Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody Drug Conjugates with High In Vitro and In Vivo Potency.
Beerli RR; Hell T; Merkel AS; Grawunder U
PLoS One; 2015; 10(7):e0131177. PubMed ID: 26132162
[TBL] [Abstract][Full Text] [Related]
24. A Platform for the Generation of Site-Specific Antibody-Drug Conjugates That Allows for Selective Reduction of Engineered Cysteines.
Coumans RGE; Ariaans GJA; Spijker HJ; Renart Verkerk P; Beusker PH; Kokke BPA; Schouten J; Blomenröhr M; van der Lee MMC; Groothuis PG; Ubink R; Dokter WHA; Timmers CM
Bioconjug Chem; 2020 Sep; 31(9):2136-2146. PubMed ID: 32697078
[TBL] [Abstract][Full Text] [Related]
25. Engineering Dual Variable Domains for the Generation of Site-Specific Antibody-Drug Conjugates.
Nanna AR; Rader C
Methods Mol Biol; 2019; 2033():39-52. PubMed ID: 31332746
[TBL] [Abstract][Full Text] [Related]
26. Characterization of cysteine-linked conjugation profiles of immunoglobulin G1 and immunoglobulin G2 antibody-drug conjugates.
Wiggins B; Liu-Shin L; Yamaguchi H; Ratnaswamy G
J Pharm Sci; 2015 Apr; 104(4):1362-72. PubMed ID: 25631158
[TBL] [Abstract][Full Text] [Related]
27. A Genetically Encoded Photocaged Cysteine for Facile Site-Specific Introduction of Conjugation-Ready Thiol Residues in Antibodies.
Osgood AO; Roy SJS; Koo D; Gu R; Chatterjee A
Bioconjug Chem; 2024 Apr; 35(4):457-464. PubMed ID: 38548654
[TBL] [Abstract][Full Text] [Related]
28. Current methods for the synthesis of homogeneous antibody-drug conjugates.
Sochaj AM; Świderska KW; Otlewski J
Biotechnol Adv; 2015 Nov; 33(6 Pt 1):775-84. PubMed ID: 25981886
[TBL] [Abstract][Full Text] [Related]
29. Site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity through linker and antibody engineering.
Pillow TH; Tien J; Parsons-Reponte KL; Bhakta S; Li H; Staben LR; Li G; Chuh J; Fourie-O'Donohue A; Darwish M; Yip V; Liu L; Leipold DD; Su D; Wu E; Spencer SD; Shen BQ; Xu K; Kozak KR; Raab H; Vandlen R; Lewis Phillips GD; Scheller RH; Polakis P; Sliwkowski MX; Flygare JA; Junutula JR
J Med Chem; 2014 Oct; 57(19):7890-9. PubMed ID: 25191794
[TBL] [Abstract][Full Text] [Related]
30. One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody-Drug Conjugates through Site-Specific Chemoenzymatic Glycan Remodeling.
Ou C; Li C; Zhang R; Yang Q; Zong G; Dai Y; Francis RL; Bournazos S; Ravetch JV; Wang LX
Bioconjug Chem; 2021 Aug; 32(8):1888-1897. PubMed ID: 34351736
[TBL] [Abstract][Full Text] [Related]
31. Assessment of reagents for selenocysteine conjugation and the stability of selenocysteine adducts.
Pedzisa L; Li X; Rader C; Roush WR
Org Biomol Chem; 2016 Jun; 14(22):5141-7. PubMed ID: 27184239
[TBL] [Abstract][Full Text] [Related]
32. Development of Solid-Phase Site-Specific Conjugation and Its Application toward Generation of Dual Labeled Antibody and Fab Drug Conjugates.
Puthenveetil S; Musto S; Loganzo F; Tumey LN; O'Donnell CJ; Graziani E
Bioconjug Chem; 2016 Apr; 27(4):1030-9. PubMed ID: 26942771
[TBL] [Abstract][Full Text] [Related]
33. Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG.
Shao S; Tsai MH; Lu J; Yu T; Jin J; Xiao D; Jiang H; Han M; Wang M; Wang J
Bioorg Med Chem Lett; 2018 May; 28(8):1363-1370. PubMed ID: 29559276
[TBL] [Abstract][Full Text] [Related]
34. Engineering THIOMABs for site-specific conjugation of thiol-reactive linkers.
Bhakta S; Raab H; Junutula JR
Methods Mol Biol; 2013; 1045():189-203. PubMed ID: 23913148
[TBL] [Abstract][Full Text] [Related]
35. Site Selection: a Case Study in the Identification of Optimal Cysteine Engineered Antibody Drug Conjugates.
Tumey LN; Li F; Rago B; Han X; Loganzo F; Musto S; Graziani EI; Puthenveetil S; Casavant J; Marquette K; Clark T; Bikker J; Bennett EM; Barletta F; Piche-Nicholas N; Tam A; O'Donnell CJ; Gerber HP; Tchistiakova L
AAPS J; 2017 Jul; 19(4):1123-1135. PubMed ID: 28439809
[TBL] [Abstract][Full Text] [Related]
36. Conformation and dynamics of interchain cysteine-linked antibody-drug conjugates as revealed by hydrogen/deuterium exchange mass spectrometry.
Pan LY; Salas-Solano O; Valliere-Douglass JF
Anal Chem; 2014 Mar; 86(5):2657-64. PubMed ID: 24512515
[TBL] [Abstract][Full Text] [Related]
37. In Vitro and In Vivo Evaluation of Cysteine Rebridged Trastuzumab-MMAE Antibody Drug Conjugates with Defined Drug-to-Antibody Ratios.
Bryant P; Pabst M; Badescu G; Bird M; McDowell W; Jamieson E; Swierkosz J; Jurlewicz K; Tommasi R; Henseleit K; Sheng X; Camper N; Manin A; Kozakowska K; Peciak K; Laurine E; Grygorash R; Kyle A; Morris D; Parekh V; Abhilash A; Choi JW; Edwards J; Frigerio M; Baker MP; Godwin A
Mol Pharm; 2015 Jun; 12(6):1872-9. PubMed ID: 25894424
[TBL] [Abstract][Full Text] [Related]
38. Bridged Cysteine Conjugations.
Bird M; Nunes J; Frigerio M
Methods Mol Biol; 2020; 2078():113-129. PubMed ID: 31643053
[TBL] [Abstract][Full Text] [Related]
39. Improving the serum stability of site-specific antibody conjugates with sulfone linkers.
Patterson JT; Asano S; Li X; Rader C; Barbas CF
Bioconjug Chem; 2014 Aug; 25(8):1402-7. PubMed ID: 25099687
[TBL] [Abstract][Full Text] [Related]
40. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system.
Zimmerman ES; Heibeck TH; Gill A; Li X; Murray CJ; Madlansacay MR; Tran C; Uter NT; Yin G; Rivers PJ; Yam AY; Wang WD; Steiner AR; Bajad SU; Penta K; Yang W; Hallam TJ; Thanos CD; Sato AK
Bioconjug Chem; 2014 Feb; 25(2):351-61. PubMed ID: 24437342
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
