244 related articles for article (PubMed ID: 26171734)
1. Xenosensor CAR mediates down-regulation of miR-122 and up-regulation of miR-122 targets in the liver.
Kazantseva YA; Yarushkin AA; Mostovich LA; Pustylnyak YA; Pustylnyak VO
Toxicol Appl Pharmacol; 2015 Oct; 288(1):26-32. PubMed ID: 26171734
[TBL] [Abstract][Full Text] [Related]
2. Peroxisome proliferator-activated receptor γ activation inhibits liver growth through miR-122-mediated downregulation of cMyc.
Yarushkin AA; Kazantseva YA; Kobelev VS; Pustylnyak YA; Pustylnyak VO
Eur J Pharmacol; 2017 Feb; 797():39-44. PubMed ID: 28095325
[TBL] [Abstract][Full Text] [Related]
3. Bioinformatic analysis of microRNA networks following the activation of the constitutive androstane receptor (CAR) in mouse liver.
Hao R; Su S; Wan Y; Shen F; Niu B; Coslo DM; Albert I; Han X; Omiecinski CJ
Biochim Biophys Acta; 2016 Sep; 1859(9):1228-1237. PubMed ID: 27080131
[TBL] [Abstract][Full Text] [Related]
4. MicroRNA-561 promotes acetaminophen-induced hepatotoxicity in HepG2 cells and primary human hepatocytes through downregulation of the nuclear receptor corepressor dosage-sensitive sex-reversal adrenal hypoplasia congenital critical region on the X chromosome, gene 1 (DAX-1).
Li M; Yang Y; He ZX; Zhou ZW; Yang T; Guo P; Zhang X; Zhou SF
Drug Metab Dispos; 2014 Jan; 42(1):44-61. PubMed ID: 24104199
[TBL] [Abstract][Full Text] [Related]
5. C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia.
Blanco-Bose WE; Murphy MJ; Ehninger A; Offner S; Dubey C; Huang W; Moore DD; Trumpp A
Hepatology; 2008 Oct; 48(4):1302-11. PubMed ID: 18798339
[TBL] [Abstract][Full Text] [Related]
6. Constitutive androstane receptor activation evokes the expression of glycolytic genes.
Yarushkin AA; Kazantseva YA; Prokopyeva EA; Markova DN; Pustylnyak YA; Pustylnyak VO
Biochem Biophys Res Commun; 2016 Sep; 478(3):1099-105. PubMed ID: 27530923
[TBL] [Abstract][Full Text] [Related]
7. The constitutive androstane receptor activator 4-[(4R,6R)-4,6-diphenyl-1,3-dioxan-2-yl]-N,N-dimethylaniline inhibits the gluconeogenic genes PEPCK and G6Pase through the suppression of HNF4α and FOXO1 transcriptional activity.
Yarushkin AA; Kachaylo EM; Pustylnyak VO
Br J Pharmacol; 2013 Apr; 168(8):1923-32. PubMed ID: 23231652
[TBL] [Abstract][Full Text] [Related]
8. Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development.
Xu H; He JH; Xiao ZD; Zhang QQ; Chen YQ; Zhou H; Qu LH
Hepatology; 2010 Oct; 52(4):1431-42. PubMed ID: 20842632
[TBL] [Abstract][Full Text] [Related]
9. Positive regulation of hepatic miR-122 expression by HNF4α.
Li ZY; Xi Y; Zhu WN; Zeng C; Zhang ZQ; Guo ZC; Hao DL; Liu G; Feng L; Chen HZ; Chen F; Lv X; Liu DP; Liang CC
J Hepatol; 2011 Sep; 55(3):602-611. PubMed ID: 21241755
[TBL] [Abstract][Full Text] [Related]
10. RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.
Cui JY; Klaassen CD
Biochim Biophys Acta; 2016 Sep; 1859(9):1198-1217. PubMed ID: 27113289
[TBL] [Abstract][Full Text] [Related]
11. Stilbene compound trans-3,4,5,4´-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver.
Dusek J; Skoda J; Holas O; Horvatova A; Smutny T; Linhartova L; Hirsova P; Kucera O; Micuda S; Braeuning A; Pavek P
Toxicol Lett; 2019 Oct; 313():1-10. PubMed ID: 31170421
[TBL] [Abstract][Full Text] [Related]
12. Nuclear receptor coactivator 6 mediates the synergistic activation of human cytochrome P-450 2C9 by the constitutive androstane receptor and hepatic nuclear factor-4alpha.
Surapureddi S; Rana R; Reddy JK; Goldstein JA
Mol Pharmacol; 2008 Sep; 74(3):913-23. PubMed ID: 18552123
[TBL] [Abstract][Full Text] [Related]
13. Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha.
Miao J; Fang S; Bae Y; Kemper JK
J Biol Chem; 2006 May; 281(21):14537-46. PubMed ID: 16492670
[TBL] [Abstract][Full Text] [Related]
14. Hepatitis C virus suppresses Hepatocyte Nuclear Factor 4 alpha, a key regulator of hepatocellular carcinoma.
Vallianou I; Dafou D; Vassilaki N; Mavromara P; Hadzopoulou-Cladaras M
Int J Biochem Cell Biol; 2016 Sep; 78():315-326. PubMed ID: 27477312
[TBL] [Abstract][Full Text] [Related]
15. CAR-mediated repression of Foxo1 transcriptional activity regulates the cell cycle inhibitor p21 in mouse livers.
Kazantseva YA; Yarushkin AA; Pustylnyak VO
Toxicology; 2014 Jul; 321():73-9. PubMed ID: 24769335
[TBL] [Abstract][Full Text] [Related]
16. Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins.
Baskin-Bey ES; Huang W; Ishimura N; Isomoto H; Bronk SF; Braley K; Craig RW; Moore DD; Gores GJ
Hepatology; 2006 Jul; 44(1):252-62. PubMed ID: 16799968
[TBL] [Abstract][Full Text] [Related]
17. Characterization of glucocorticoid receptor and hepatocyte nuclear factor 4alpha (HNF4alpha) binding to the hnf4alpha gene in the liver.
Bailly A; Briançon N; Weiss MC
Biochimie; 2009 Sep; 91(9):1095-103. PubMed ID: 19540905
[TBL] [Abstract][Full Text] [Related]
18. An HNF4α-microRNA-194/192 signaling axis maintains hepatic cell function.
Morimoto A; Kannari M; Tsuchida Y; Sasaki S; Saito C; Matsuta T; Maeda T; Akiyama M; Nakamura T; Sakaguchi M; Nameki N; Gonzalez FJ; Inoue Y
J Biol Chem; 2017 Jun; 292(25):10574-10585. PubMed ID: 28465351
[TBL] [Abstract][Full Text] [Related]
19. Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear constitutive active/androstane receptor (CAR) in the cytoplasm of mouse primary hepatocytes.
Koike C; Moore R; Negishi M
Mol Pharmacol; 2007 May; 71(5):1217-21. PubMed ID: 17314319
[TBL] [Abstract][Full Text] [Related]
20. Regulation of gene expression by CAR: an update.
Kobayashi K; Hashimoto M; Honkakoski P; Negishi M
Arch Toxicol; 2015 Jul; 89(7):1045-55. PubMed ID: 25975989
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
