BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 26177608)

  • 1. Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor.
    Keshari KR; Wilson DM; Van Criekinge M; Sriram R; Koelsch BL; Wang ZJ; VanBrocklin HF; Peehl DM; O'Brien T; Sampath D; Carano RA; Kurhanewicz J
    Prostate; 2015 Oct; 75(14):1601-9. PubMed ID: 26177608
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combined hyperpolarized
    Hansen AE; Gutte H; Holst P; Johannesen HH; Rahbek S; Clemmensen AE; Larsen MME; Schøier C; Ardenkjaer-Larsen J; Klausen TL; Kristensen AT; Kjaer A
    Eur J Radiol; 2018 Jun; 103():6-12. PubMed ID: 29803387
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolic reprogramming and validation of hyperpolarized 13C lactate as a prostate cancer biomarker using a human prostate tissue slice culture bioreactor.
    Keshari KR; Sriram R; Van Criekinge M; Wilson DM; Wang ZJ; Vigneron DB; Peehl DM; Kurhanewicz J
    Prostate; 2013 Aug; 73(11):1171-81. PubMed ID: 23532911
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Real-time measurement of hyperpolarized lactate production and efflux as a biomarker of tumor aggressiveness in an MR compatible 3D cell culture bioreactor.
    Sriram R; Van Criekinge M; Hansen A; Wang ZJ; Vigneron DB; Wilson DM; Keshari KR; Kurhanewicz J
    NMR Biomed; 2015 Sep; 28(9):1141-9. PubMed ID: 26202449
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Utilization of
    Mudd SR; Voorbach MJ; Cheng D; Cheng M; Guo J; Gao W; Buchanan FG; Tse C; Wilsbacher J
    J Pharmacol Exp Ther; 2019 Dec; 371(3):583-589. PubMed ID: 31562200
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multimodal assessment of in vivo metabolism with hyperpolarized [1-13C]MR spectroscopy and 18F-FDG PET imaging in hepatocellular carcinoma tumor-bearing rats.
    Menzel MI; Farrell EV; Janich MA; Khegai O; Wiesinger F; Nekolla S; Otto AM; Haase A; Schulte RF; Schwaiger M
    J Nucl Med; 2013 Jul; 54(7):1113-9. PubMed ID: 23596002
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Divergent metabolic responses dictate vulnerability to NAMPT inhibition in ovarian cancer.
    Kudo K; Nomura M; Sakamoto Y; Ito S; Morita M; Kawai M; Yamashita Y; Ito K; Yamada H; Shima H; Yaegashi N; Tanuma N
    FEBS Lett; 2020 May; 594(9):1379-1388. PubMed ID: 31950503
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized
    Sriram R; Van Criekinge M; DeLos Santos J; Ahamed F; Qin H; Nolley R; Santos RD; Tabatabai ZL; Bok RA; Keshari KR; Vigneron DB; Peehl DM; Kurhanewicz J
    Cancers (Basel); 2020 Feb; 12(3):. PubMed ID: 32110965
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolomics analysis of metabolic effects of nicotinamide phosphoribosyltransferase (NAMPT) inhibition on human cancer cells.
    Tolstikov V; Nikolayev A; Dong S; Zhao G; Kuo MS
    PLoS One; 2014; 9(12):e114019. PubMed ID: 25486521
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase.
    Zabka TS; Singh J; Dhawan P; Liederer BM; Oeh J; Kauss MA; Xiao Y; Zak M; Lin T; McCray B; La N; Nguyen T; Beyer J; Farman C; Uppal H; Dragovich PS; O'Brien T; Sampath D; Misner DL
    Toxicol Sci; 2015 Mar; 144(1):163-72. PubMed ID: 25505128
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NAMPT inhibitor and metabolite protect mouse brain from cryoinjury through distinct mechanisms.
    Zhang XQ; Lu JT; Jiang WX; Lu YB; Wu M; Wei EQ; Zhang WP; Tang C
    Neuroscience; 2015 Apr; 291():230-40. PubMed ID: 25684751
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Simultaneous Hyperpolarized 13C-Pyruvate MRI and 18F-FDG PET (HyperPET) in 10 Dogs with Cancer.
    Gutte H; Hansen AE; Larsen MM; Rahbek S; Henriksen ST; Johannesen HH; Ardenkjaer-Larsen J; Kristensen AT; Højgaard L; Kjær A
    J Nucl Med; 2015 Nov; 56(11):1786-92. PubMed ID: 26338899
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD
    Chmielewski JP; Bowlby SC; Wheeler FB; Shi L; Sui G; Davis AL; Howard TD; D'Agostino RB; Miller LD; Sirintrapun SJ; Cramer SD; Kridel SJ
    Mol Cancer Res; 2018 Nov; 16(11):1687-1700. PubMed ID: 30076241
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cardiotoxicity Associated with Nicotinamide Phosphoribosyltransferase Inhibitors in Rodents and in Rat and Human-Derived Cells Lines.
    Misner DL; Kauss MA; Singh J; Uppal H; Bruening-Wright A; Liederer BM; Lin T; McCray B; La N; Nguyen T; Sampath D; Dragovich PS; O'Brien T; Zabka TS
    Cardiovasc Toxicol; 2017 Jul; 17(3):307-318. PubMed ID: 27783203
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer.
    Sampath D; Zabka TS; Misner DL; O'Brien T; Dragovich PS
    Pharmacol Ther; 2015 Jul; 151():16-31. PubMed ID: 25709099
    [TBL] [Abstract][Full Text] [Related]  

  • 16. EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition.
    Zucal C; D'Agostino VG; Casini A; Mantelli B; Thongon N; Soncini D; Caffa I; Cea M; Ballestrero A; Quattrone A; Indraccolo S; Nencioni A; Provenzani A
    BMC Cancer; 2015 Nov; 15():855. PubMed ID: 26542945
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures.
    Cox BL; Erickson-Bhatt S; Szulczewski JM; Squirrell JM; Ludwig KD; Macdonald EB; Swader R; Ponik SM; Eliceiri KW; Fain SB
    Magn Reson Med; 2019 May; 81(5):3379-3391. PubMed ID: 30652350
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NAMPT protects against 6-hydroxydopamine-induced neurotoxicity in PC12 cells through modulating SIRT1 activity.
    Zou XD; Guo SQ; Hu ZW; Li WL
    Mol Med Rep; 2016 May; 13(5):4058-64. PubMed ID: 27035562
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting NAMPT for Therapeutic Intervention in Cancer and Inflammation: Structure-Based Drug Design and Biological Screening.
    Pulla VK; Sriram DS; Soni V; Viswanadha S; Sriram D; Yogeeswari P
    Chem Biol Drug Des; 2015 Oct; 86(4):881-94. PubMed ID: 25850461
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells.
    Yang NC; Song TY; Chang YZ; Chen MY; Hu ML
    Biogerontology; 2015 Feb; 16(1):31-42. PubMed ID: 25146190
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.