BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

570 related articles for article (PubMed ID: 26180030)

  • 1. Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway.
    Ho CH; Hsu JL; Liu SP; Hsu LC; Chang WL; Chao CC; Guh JH
    Prostate; 2015 Sep; 75(13):1454-66. PubMed ID: 26180030
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery.
    Lu PH; Kung FL; Kuo SC; Chueh SC; Guh JH
    Naunyn Schmiedebergs Arch Pharmacol; 2006 Dec; 374(3):223-33. PubMed ID: 17102938
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.
    Chen YC; Lu PH; Pan SL; Teng CM; Kuo SC; Lin TP; Ho YF; Huang YC; Guh JH
    Biochem Pharmacol; 2007 Jun; 74(1):10-9. PubMed ID: 17475221
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin-induced apoptosis in castration-resistant prostate cancer.
    Ye PC; Leu WJ; Yeh TY; Hsu YT; Lin YC; Wei ZY; Chen YC; Chiang YC; Hsu JL; Chan SH; Hsu LC; Chern JW; Yu CW; Guh JH
    Prostate; 2024 May; 84(6):605-619. PubMed ID: 38375594
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ascleposide, a natural cardenolide, induces anticancer signaling in human castration-resistant prostatic cancer through Na
    Leu WJ; Wang CT; Hsu JL; Chen IS; Chang HS; Guh JH
    Prostate; 2020 Mar; 80(4):305-318. PubMed ID: 31905252
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines.
    Ling YH; Jiang JD; Holland JF; Perez-Soler R
    Mol Pharmacol; 2002 Sep; 62(3):529-38. PubMed ID: 12181429
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dependency of 2-methoxyestradiol-induced mitochondrial apoptosis on mitotic spindle network impairment and prometaphase arrest in human Jurkat T cells.
    Lee ST; Lee JY; Han CR; Kim YH; Jun do Y; Taub D; Kim YH
    Biochem Pharmacol; 2015 Apr; 94(4):257-69. PubMed ID: 25732194
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinase.
    Chang WL; Chang CS; Chiang PC; Ho YF; Liu JF; Chang KW; Guh JH
    Br J Pharmacol; 2010 Aug; 160(7):1677-89. PubMed ID: 20649571
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulation.
    Yu CC; Wu PJ; Hsu JL; Ho YF; Hsu LC; Chang YJ; Chang HS; Chen IS; Guh JH
    Prostate; 2013 Jan; 73(2):133-45. PubMed ID: 22674285
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of microtubule-damage, mitotic arrest, Bcl-2 phosphorylation, Bak activation, and mitochondria-dependent caspase cascade is involved in human Jurkat T-cell apoptosis by aruncin B from Aruncus dioicus var. kamtschaticus.
    Han CR; Jun do Y; Woo HJ; Jeong SY; Woo MH; Kim YH
    Bioorg Med Chem Lett; 2012 Jan; 22(2):945-53. PubMed ID: 22197393
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between endoplasmic reticulum stress and mitochondrial insult.
    Chan ML; Liang JW; Hsu LC; Chang WL; Lee SS; Guh JH
    Naunyn Schmiedebergs Arch Pharmacol; 2015 Nov; 388(11):1223-36. PubMed ID: 26246051
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prometaphase arrest-dependent phosphorylation of Bcl-2 family proteins and activation of mitochondrial apoptotic pathway are associated with 17α-estradiol-induced apoptosis in human Jurkat T cells.
    Han CR; Jun do Y; Kim YH; Lee JY; Kim YH
    Biochim Biophys Acta; 2013 Oct; 1833(10):2220-32. PubMed ID: 23707954
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
    Viola G; Cecconet L; Leszl A; Basso G; Brun P; Salvador A; Dall'Acqua F; Diana P; Barraja P; Cirrincione G
    Cancer Chemother Pharmacol; 2009 Nov; 64(6):1235-51. PubMed ID: 19363609
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Moniliformediquinone induces in vitro and in vivo antitumor activity through glutathione involved DNA damage response and mitochondrial stress in human hormone refractory prostate cancer.
    Hsu JL; Lee YJ; Leu WJ; Dong YS; Pan SL; Uang BJ; Guh JH
    J Urol; 2014 May; 191(5):1429-38. PubMed ID: 24316097
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell.
    Hasanpourghadi M; Karthikeyan C; Pandurangan AK; Looi CY; Trivedi P; Kobayashi K; Tanaka K; Wong WF; Mustafa MR
    J Exp Clin Cancer Res; 2016 Mar; 35():58. PubMed ID: 27030360
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CIL-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer PC-3 cell line.
    Huang YT; Huang DM; Guh JH; Chen IL; Tzeng CC; Teng CM
    J Biol Chem; 2005 Jan; 280(4):2771-9. PubMed ID: 15536083
    [TBL] [Abstract][Full Text] [Related]  

  • 17. KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora A activity.
    Yu CC; Liu SP; Hsu JL; Hsu JT; Kudryavtsev KV; Guh JH
    J Biomed Sci; 2015 Jan; 22(1):2. PubMed ID: 25563361
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of JNK2 and JNK3 by JNK inhibitor IX induces prometaphase arrest-dependent apoptotic cell death in human Jurkat T cells.
    Jang WY; Lee JY; Lee ST; Jun do Y; Kim YH
    Biochem Biophys Res Commun; 2014 Sep; 452(3):845-51. PubMed ID: 25218503
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
    Kuo CC; Hsieh HP; Pan WY; Chen CP; Liou JP; Lee SJ; Chang YL; Chen LT; Chen CT; Chang JY
    Cancer Res; 2004 Jul; 64(13):4621-8. PubMed ID: 15231674
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J; Pang Y; Sheng J; Wang Y; Chen J; Hu J; Huang L; Li X
    Biochem Pharmacol; 2015 Sep; 97(1):51-61. PubMed ID: 26212540
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.