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8. Dominantly inherited constitutional epigenetic silencing of MLH1 in a cancer-affected family is linked to a single nucleotide variant within the 5'UTR. Hitchins MP; Rapkins RW; Kwok CT; Srivastava S; Wong JJ; Khachigian LM; Polly P; Goldblatt J; Ward RL Cancer Cell; 2011 Aug; 20(2):200-13. PubMed ID: 21840485 [TBL] [Abstract][Full Text] [Related]
9. Intensity-dependent constitutional MLH1 promoter methylation leads to early onset of colorectal cancer by affecting both alleles. Auclair J; Vaissière T; Desseigne F; Lasset C; Bonadona V; Giraud S; Saurin JC; Joly MO; Leroux D; Faivre L; Audoynaud C; Montmain G; Ruano E; Herceg Z; Puisieux A; Wang Q Genes Chromosomes Cancer; 2011 Mar; 50(3):178-85. PubMed ID: 21213371 [TBL] [Abstract][Full Text] [Related]
10. Highly sensitive MLH1 methylation analysis in blood identifies a cancer patient with low-level mosaic MLH1 epimutation. Dámaso E; Canet-Hermida J; Vargas-Parra G; Velasco À; Marín F; Darder E; Del Valle J; Fernández A; Izquierdo À; Mateu G; Oliveras G; Escribano C; Piñol V; Uchima HI; Soto JL; Hitchins M; Farrés R; Lázaro C; Queralt B; Brunet J; Capellá G; Pineda M Clin Epigenetics; 2019 Nov; 11(1):171. PubMed ID: 31779681 [TBL] [Abstract][Full Text] [Related]
11. Further evidence for heritability of an epimutation in one of 12 cases with MLH1 promoter methylation in blood cells clinically displaying HNPCC. Morak M; Schackert HK; Rahner N; Betz B; Ebert M; Walldorf C; Royer-Pokora B; Schulmann K; von Knebel-Doeberitz M; Dietmaier W; Keller G; Kerker B; Leitner G; Holinski-Feder E Eur J Hum Genet; 2008 Jul; 16(7):804-11. PubMed ID: 18301449 [TBL] [Abstract][Full Text] [Related]
12. MLH1-methylated endometrial cancer under 60 years of age as the "sentinel" cancer in female carriers of high-risk constitutional MLH1 epimutation. Hitchins MP; Alvarez R; Zhou L; Aguirre F; Dámaso E; Pineda M; Capella G; Wong JJ; Yuan X; Ryan SR; Sathe DS; Baxter MD; Cannon T; Biswas R; DeMarco T; Grzelak D; Hampel H; Pearlman R Gynecol Oncol; 2023 Apr; 171():129-140. PubMed ID: 36893489 [TBL] [Abstract][Full Text] [Related]
13. Identification of new cases of early-onset colorectal cancer with an MLH1 epimutation in an ethnically diverse South African cohort. Hitchins MP; Owens SE; Kwok CT; Godsmark G; Algar UF; Ramesar RS Clin Genet; 2011 Nov; 80(5):428-34. PubMed ID: 21375527 [TBL] [Abstract][Full Text] [Related]
14. Prevalence of MLH1 constitutional epimutations as a cause of Lynch syndrome in unselected versus selected consecutive series of patients with colorectal cancer. Castillejo A; Hernández-Illán E; Rodriguez-Soler M; Pérez-Carbonell L; Egoavil C; Barberá VM; Castillejo MI; Guarinos C; Martínez-de-Dueñas E; Juan MJ; Sánchez-Heras AB; García-Casado Z; Ruiz-Ponte C; Brea-Fernández A; Juárez M; Bujanda L; Clofent J; Llor X; Andreu M; Castells A; Carracedo A; Alenda C; Payá A; Jover R; Soto JL J Med Genet; 2015 Jul; 52(7):498-502. PubMed ID: 25908759 [TBL] [Abstract][Full Text] [Related]
15. DNA methylation, epimutations and cancer predisposition. Dobrovic A; Kristensen LS Int J Biochem Cell Biol; 2009 Jan; 41(1):34-9. PubMed ID: 18835361 [TBL] [Abstract][Full Text] [Related]
16. Germline epimutation: A basis for epigenetic disease in humans. Martin DI; Ward R; Suter CM Ann N Y Acad Sci; 2005; 1054():68-77. PubMed ID: 16339653 [TBL] [Abstract][Full Text] [Related]
17. Germline epimutation of MLH1 in individuals with multiple cancers. Suter CM; Martin DI; Ward RL Nat Genet; 2004 May; 36(5):497-501. PubMed ID: 15064764 [TBL] [Abstract][Full Text] [Related]
18. Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer. Hitchins MP; Ward RL J Med Genet; 2009 Dec; 46(12):793-802. PubMed ID: 19564652 [TBL] [Abstract][Full Text] [Related]
19. MLH1 germline epimutations in selected patients with early-onset non-polyposis colorectal cancer. Valle L; Carbonell P; Fernandez V; Dotor AM; Sanz M; Benitez J; Urioste M Clin Genet; 2007 Mar; 71(3):232-7. PubMed ID: 17309645 [TBL] [Abstract][Full Text] [Related]
20. Concomitant mutation and epimutation of the MLH1 gene in a Lynch syndrome family. Cini G; Carnevali I; Quaia M; Chiaravalli AM; Sala P; Giacomini E; Maestro R; Tibiletti MG; Viel A Carcinogenesis; 2015 Apr; 36(4):452-8. PubMed ID: 25742745 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]