These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

444 related articles for article (PubMed ID: 26183715)

  • 1. Treatment with cucurbitacin B alone and in combination with gefitinib induces cell cycle inhibition and apoptosis via EGFR and JAK/STAT pathway in human colorectal cancer cell lines.
    Yar Saglam AS; Alp E; Elmazoglu Z; Menevse S
    Hum Exp Toxicol; 2016 May; 35(5):526-43. PubMed ID: 26183715
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of pancreatic cancer cell growth by cucurbitacin B through modulation of signal transducer and activator of transcription 3 signaling.
    Zhang M; Sun C; Shan X; Yang X; Li-Ling J; Deng Y
    Pancreas; 2010 Aug; 39(6):923-9. PubMed ID: 20182390
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells.
    Thoennissen NH; Iwanski GB; Doan NB; Okamoto R; Lin P; Abbassi S; Song JH; Yin D; Toh M; Xie WD; Said JW; Koeffler HP
    Cancer Res; 2009 Jul; 69(14):5876-84. PubMed ID: 19605406
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Calcitriol and its analogues enhance the antiproliferative activity of gefitinib in breast cancer cells.
    Segovia-Mendoza M; Díaz L; González-González ME; Martínez-Reza I; García-Quiroz J; Prado-Garcia H; Ibarra-Sánchez MJ; Esparza-López J; Larrea F; García-Becerra R
    J Steroid Biochem Mol Biol; 2015 Apr; 148():122-31. PubMed ID: 25510900
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enediyne lidamycin enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitor, gefitinib, in epidermoid carcinoma A431 cells and lung carcinoma H460 cells.
    Liu H; Li L; Li XQ; Liu XJ; Zhen YS
    Anticancer Drugs; 2009 Jan; 20(1):41-9. PubMed ID: 19342999
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Type II cGMP‑dependent protein kinase inhibits EGF‑induced JAK/STAT signaling in gastric cancer cells.
    Wu M; Wu Y; Lan T; Jiang L; Qian H; Chen Y
    Mol Med Rep; 2016 Aug; 14(2):1849-56. PubMed ID: 27357186
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cells.
    Premkumar DR; Jane EP; Pollack IF
    Cancer Biol Ther; 2015; 16(2):233-43. PubMed ID: 25482928
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PANC-1 pancreatic cancer cell growth inhibited by cucurmosin alone and in combination with an epidermal growth factor receptor-targeted drug.
    Wang C; Yang A; Zhang B; Yin Q; Huang H; Chen M; Xie J
    Pancreas; 2014 Mar; 43(2):291-7. PubMed ID: 24518510
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synergistic anti-tumor effect of combined inhibition of EGFR and JAK/STAT3 pathways in human ovarian cancer.
    Wen W; Wu J; Liu L; Tian Y; Buettner R; Hsieh MY; Horne D; Dellinger TH; Han ES; Jove R; Yim JH
    Mol Cancer; 2015 May; 14():100. PubMed ID: 25928246
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Icariside II induces apoptosis via inhibition of the EGFR pathways in A431 human epidermoid carcinoma cells.
    Wu J; Zuo F; Du J; Wong PF; Qin H; Xu J
    Mol Med Rep; 2013 Aug; 8(2):597-602. PubMed ID: 23807305
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeted constitutive activation of signal transducer and activator of transcription 3 in human hepatocellular carcinoma cells by cucurbitacin B.
    Zhang M; Zhang H; Sun C; Shan X; Yang X; Li-Ling J; Deng Y
    Cancer Chemother Pharmacol; 2009 Mar; 63(4):635-42. PubMed ID: 18521604
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels.
    Helfrich BA; Raben D; Varella-Garcia M; Gustafson D; Chan DC; Bemis L; Coldren C; Barón A; Zeng C; Franklin WA; Hirsch FR; Gazdar A; Minna J; Bunn PA
    Clin Cancer Res; 2006 Dec; 12(23):7117-25. PubMed ID: 17145836
    [TBL] [Abstract][Full Text] [Related]  

  • 13. JAK/STAT pathway plays a critical role in the proinflammatory gene expression and apoptosis of RAW264.7 cells induced by trichothecenes as DON and T-2 toxin.
    Wang X; Liu Q; Ihsan A; Huang L; Dai M; Hao H; Cheng G; Liu Z; Wang Y; Yuan Z
    Toxicol Sci; 2012 Jun; 127(2):412-24. PubMed ID: 22454431
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autophagy Inhibition Overcomes the Antagonistic Effect Between Gefitinib and Cisplatin in Epidermal Growth Factor Receptor Mutant Non--Small-Cell Lung Cancer Cells.
    Liu JT; Li WC; Gao S; Wang F; Li XQ; Yu HQ; Fan LL; Wei W; Wang H; Sun GP
    Clin Lung Cancer; 2015 Sep; 16(5):e55-66. PubMed ID: 25979647
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of pemetrexed, gefitinib, and their combination on human colorectal cancer cells.
    Zhang G; Xie X; Liu T; Yang J; Jiao S
    Cancer Chemother Pharmacol; 2013 Oct; 72(4):767-75. PubMed ID: 23959460
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cucurbitacin B controls M2 macrophage polarization to suppresses metastasis via targeting JAK-2/STAT3 signalling pathway in colorectal cancer.
    Zhang H; Zhao B; Wei H; Zeng H; Sheng D; Zhang Y
    J Ethnopharmacol; 2022 Apr; 287():114915. PubMed ID: 34954267
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of the therapeutic potential of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in preclinical models of bladder cancer.
    Dominguez-Escrig JL; Kelly JD; Neal DE; King SM; Davies BR
    Clin Cancer Res; 2004 Jul; 10(14):4874-84. PubMed ID: 15269164
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-alpha in head and neck cancer cells in vitro and in vivo.
    Bruzzese F; Di Gennaro E; Avallone A; Pepe S; Arra C; Caraglia M; Tagliaferri P; Budillon A
    Clin Cancer Res; 2006 Jan; 12(2):617-25. PubMed ID: 16428508
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Efficacy of Zhonglun'a-decoction-containing serum on fibroblast-like synoviocyte apoptosis in rats with collagen-induced arthritis via inhibiting Janus kinase/signal transducer and activator of transcription signaling pathway.
    Yang Y; Dong Q; Ma C; Li Y; Chen K; Zhang S; Zhang Y
    J Tradit Chin Med; 2019 Apr; 39(2):181-190. PubMed ID: 32186040
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin.
    Liu T; Peng H; Zhang M; Deng Y; Wu Z
    Eur J Pharmacol; 2010 Sep; 641(1):15-22. PubMed ID: 20483353
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.