These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Evaluation and optimization of compound solubilization and delivery methods in a two-tiered ion channel lead optimization triage. Hendricson AW; Gallagher L; Matchett M; Ferrante M; Spence S; Paiva T; Shou W; Tertyshnikova S; Krambis M; Post-Munson D; Zhang L; Knox R Assay Drug Dev Technol; 2012 Apr; 10(2):202-11. PubMed ID: 22085018 [TBL] [Abstract][Full Text] [Related]
4. High-throughput viability assay using an autonomously bioluminescent cell line with a bacterial Lux reporter. Class B; Thorne N; Aguisanda F; Southall N; McKew JC; Zheng W J Lab Autom; 2015 Apr; 20(2):164-74. PubMed ID: 25447977 [TBL] [Abstract][Full Text] [Related]
5. Quality control procedures for dose-response curve generation using nanoliter dispense technologies. Quintero C; Rosenstein C; Hughes B; Middleton R; Kariv I J Biomol Screen; 2007 Sep; 12(6):891-9. PubMed ID: 17517899 [TBL] [Abstract][Full Text] [Related]
7. High throughput sonication: evaluation for compound solubilization. Oldenburg K; Pooler D; Scudder K; Lipinski C; Kelly M Comb Chem High Throughput Screen; 2005 Sep; 8(6):499-512. PubMed ID: 16178809 [TBL] [Abstract][Full Text] [Related]
8. High throughput solubility measurement with automated polarized light microscopy analysis. Sugano K; Kato T; Suzuki K; Keiko K; Sujaku T; Mano T J Pharm Sci; 2006 Oct; 95(10):2115-22. PubMed ID: 16871512 [TBL] [Abstract][Full Text] [Related]
9. Protein precipitation and denaturation by dimethyl sulfoxide. Arakawa T; Kita Y; Timasheff SN Biophys Chem; 2007 Dec; 131(1-3):62-70. PubMed ID: 17904724 [TBL] [Abstract][Full Text] [Related]
10. Achieving accurate compound concentration in cell-based screening: validation of acoustic droplet ejection technology. Grant RJ; Roberts K; Pointon C; Hodgson C; Womersley L; Jones DC; Tang E J Biomol Screen; 2009 Jun; 14(5):452-9. PubMed ID: 19498082 [TBL] [Abstract][Full Text] [Related]
11. In silico estimation of DMSO solubility of organic compounds for bioscreening. Balakin KV; Ivanenkov YA; Skorenko AV; Nikolsky YV; Savchuk NP; Ivashchenko AA J Biomol Screen; 2004 Feb; 9(1):22-31. PubMed ID: 15006145 [TBL] [Abstract][Full Text] [Related]
12. Streamlined system for purifying and quantifying a diverse library of compounds and the effect of compound concentration measurements on the accurate interpretation of biological assay results. Popa-Burke IG; Issakova O; Arroway JD; Bernasconi P; Chen M; Coudurier L; Galasinski S; Jadhav AP; Janzen WP; Lagasca D; Liu D; Lewis RS; Mohney RP; Sepetov N; Sparkman DA; Hodge CN Anal Chem; 2004 Dec; 76(24):7278-87. PubMed ID: 15595870 [TBL] [Abstract][Full Text] [Related]
13. Detailed study of precipitation of a poorly water soluble test compound using methodologies as in activity and solubility screening - mixing and automation effects. Gillespie C; Kennedy AR; Edwards D; Dowden L; Daublain P; Halling P Comb Chem High Throughput Screen; 2013 Sep; 16(8):636-43. PubMed ID: 23713459 [TBL] [Abstract][Full Text] [Related]
14. Cell dispensing in low-volume range with the immediate drop-on-demand technology (I-DOT). Schober L; Büttner E; Laske C; Traube A; Brode T; Traube AF; Bauernhansl T J Lab Autom; 2015 Apr; 20(2):154-63. PubMed ID: 25524492 [TBL] [Abstract][Full Text] [Related]
15. Biological assay challenges from compound solubility: strategies for bioassay optimization. Di L; Kerns EH Drug Discov Today; 2006 May; 11(9-10):446-51. PubMed ID: 16635808 [TBL] [Abstract][Full Text] [Related]
17. Cross contamination associated with the use of multiwell culture plates for cytotoxicity assessment of volatile chemicals. Blein O; Ronot X; Adolphe M Cytotechnology; 1991 May; 6(1):79-82. PubMed ID: 1367403 [TBL] [Abstract][Full Text] [Related]
18. Preparation and characterization of amorphous amphotericin B nanoparticles for oral administration through liquid antisolvent precipitation. Zu Y; Sun W; Zhao X; Wang W; Li Y; Ge Y; Liu Y; Wang K Eur J Pharm Sci; 2014 Mar; 53():109-17. PubMed ID: 24345795 [TBL] [Abstract][Full Text] [Related]
19. Protein precipitation In Vitro as a measure of chemical-induced cytotoxicity: an EDIT sub-programme. Novillo A; Ekwall B; Castaño A Altern Lab Anim; 2001; 29(3):309-24. PubMed ID: 11387026 [TBL] [Abstract][Full Text] [Related]
20. Toxicity profiles and solvent-toxicant interference in the planarian Schmidtea mediterranea after dimethylsulfoxide (DMSO) exposure. Stevens AS; Pirotte N; Plusquin M; Willems M; Neyens T; Artois T; Smeets K J Appl Toxicol; 2015 Mar; 35(3):319-26. PubMed ID: 24964768 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]