208 related articles for article (PubMed ID: 26188093)
1. Cereblon is recruited to aggresome and shows cytoprotective effect against ubiquitin-proteasome system dysfunction.
Sawamura N; Wakabayashi S; Matsumoto K; Yamada H; Asahi T
Biochem Biophys Res Commun; 2015 Sep; 464(4):1054-1059. PubMed ID: 26188093
[TBL] [Abstract][Full Text] [Related]
2. A mental retardation-linked nonsense mutation in cereblon is rescued by proteasome inhibition.
Xu G; Jiang X; Jaffrey SR
J Biol Chem; 2013 Oct; 288(41):29573-85. PubMed ID: 23983124
[TBL] [Abstract][Full Text] [Related]
3. Cereblon-mediated degradation of the amyloid precursor protein via the ubiquitin-proteasome pathway.
Kurihara T; Asahi T; Sawamura N
Biochem Biophys Res Commun; 2020 Mar; 524(1):236-241. PubMed ID: 31983437
[TBL] [Abstract][Full Text] [Related]
4. Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon.
Akuffo AA; Alontaga AY; Metcalf R; Beatty MS; Becker A; McDaniel JM; Hesterberg RS; Goodheart WE; Gunawan S; Ayaz M; Yang Y; Karim MR; Orobello ME; Daniel K; Guida W; Yoder JA; Rajadhyaksha AM; Schönbrunn E; Lawrence HR; Lawrence NJ; Epling-Burnette PK
J Biol Chem; 2018 Apr; 293(16):6187-6200. PubMed ID: 29449372
[TBL] [Abstract][Full Text] [Related]
5. Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).
Gandhi AK; Kang J; Havens CG; Conklin T; Ning Y; Wu L; Ito T; Ando H; Waldman MF; Thakurta A; Klippel A; Handa H; Daniel TO; Schafer PH; Chopra R
Br J Haematol; 2014 Mar; 164(6):811-21. PubMed ID: 24328678
[TBL] [Abstract][Full Text] [Related]
6. A novel effect of thalidomide and its analogs: suppression of cereblon ubiquitination enhances ubiquitin ligase function.
Liu Y; Huang X; He X; Zhou Y; Jiang X; Chen-Kiang S; Jaffrey SR; Xu G
FASEB J; 2015 Dec; 29(12):4829-39. PubMed ID: 26231201
[TBL] [Abstract][Full Text] [Related]
7. Positive selection of cereblon modified function including its E3 ubiquitin ligase activity and binding efficiency with AMPK.
Onodera W; Asahi T; Sawamura N
Mol Phylogenet Evol; 2019 Jun; 135():78-85. PubMed ID: 30836149
[TBL] [Abstract][Full Text] [Related]
8. Cereblon inhibits proteasome activity by binding to the 20S core proteasome subunit beta type 4.
Lee KM; Lee J; Park CS
Biochem Biophys Res Commun; 2012 Oct; 427(3):618-22. PubMed ID: 23026050
[TBL] [Abstract][Full Text] [Related]
9. Chemical approaches to targeted protein degradation through modulation of the ubiquitin-proteasome pathway.
Collins I; Wang H; Caldwell JJ; Chopra R
Biochem J; 2017 Mar; 474(7):1127-1147. PubMed ID: 28298557
[TBL] [Abstract][Full Text] [Related]
10. Hypnotic effect of thalidomide is independent of teratogenic ubiquitin/proteasome pathway.
Hirose Y; Kitazono T; Sezaki M; Abe M; Sakimura K; Funato H; Handa H; Vogt KE; Yanagisawa M
Proc Natl Acad Sci U S A; 2020 Sep; 117(37):23106-23112. PubMed ID: 32848052
[TBL] [Abstract][Full Text] [Related]
11. Rescue of Learning and Memory Deficits in the Human Nonsyndromic Intellectual Disability Cereblon Knock-Out Mouse Model by Targeting the AMP-Activated Protein Kinase-mTORC1 Translational Pathway.
Bavley CC; Rice RC; Fischer DK; Fakira AK; Byrne M; Kosovsky M; Rizzo BK; Del Prete D; Alaedini A; Morón JA; Higgins JJ; D'Adamio L; Rajadhyaksha AM
J Neurosci; 2018 Mar; 38(11):2780-2795. PubMed ID: 29459374
[TBL] [Abstract][Full Text] [Related]
12. Targeting cereblon in hematologic malignancies.
Fuchs O
Blood Rev; 2023 Jan; 57():100994. PubMed ID: 35933246
[TBL] [Abstract][Full Text] [Related]
13. Parkin co-regulated gene is involved in aggresome formation and autophagy in response to proteasomal impairment.
Taylor JM; Brody KM; Lockhart PJ
Exp Cell Res; 2012 Oct; 318(16):2059-70. PubMed ID: 22652456
[TBL] [Abstract][Full Text] [Related]
14. Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology.
Ito T; Yamaguchi Y; Handa H
Cell Chem Biol; 2021 Jul; 28(7):987-999. PubMed ID: 34033753
[TBL] [Abstract][Full Text] [Related]
15. Dysregulation of large-conductance Ca2+-activated K+ channel expression in nonsyndromal mental retardation due to a cereblon p.R419X mutation.
Higgins JJ; Hao J; Kosofsky BE; Rajadhyaksha AM
Neurogenetics; 2008 Jul; 9(3):219-23. PubMed ID: 18414909
[TBL] [Abstract][Full Text] [Related]
16. A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Matyskiela ME; Lu G; Ito T; Pagarigan B; Lu CC; Miller K; Fang W; Wang NY; Nguyen D; Houston J; Carmel G; Tran T; Riley M; Nosaka L; Lander GC; Gaidarova S; Xu S; Ruchelman AL; Handa H; Carmichael J; Daniel TO; Cathers BE; Lopez-Girona A; Chamberlain PP
Nature; 2016 Jul; 535(7611):252-7. PubMed ID: 27338790
[TBL] [Abstract][Full Text] [Related]
17. UCH-L1 aggresome formation in response to proteasome impairment indicates a role in inclusion formation in Parkinson's disease.
Ardley HC; Scott GB; Rose SA; Tan NG; Robinson PA
J Neurochem; 2004 Jul; 90(2):379-91. PubMed ID: 15228595
[TBL] [Abstract][Full Text] [Related]
18. Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon.
Nguyen TV; Lee JE; Sweredoski MJ; Yang SJ; Jeon SJ; Harrison JS; Yim JH; Lee SG; Handa H; Kuhlman B; Jeong JS; Reitsma JM; Park CS; Hess S; Deshaies RJ
Mol Cell; 2016 Mar; 61(6):809-20. PubMed ID: 26990986
[TBL] [Abstract][Full Text] [Related]
19. A missense mutation in the
Sheereen A; Alaamery M; Bawazeer S; Al Yafee Y; Massadeh S; Eyaid W
J Med Genet; 2017 Apr; 54(4):236-240. PubMed ID: 28143899
[TBL] [Abstract][Full Text] [Related]
20. Cereblon: promise and challenges for combating human diseases.
Kim HK; Seol JE; Ahn SW; Jeon S; Park CS; Han J
Pflugers Arch; 2021 Nov; 473(11):1695-1711. PubMed ID: 34553266
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]