BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 26189795)

  • 1. Targeting hedgehog signaling reduces self-renewal in embryonal rhabdomyosarcoma.
    Satheesha S; Manzella G; Bovay A; Casanova EA; Bode PK; Belle R; Feuchtgruber S; Jaaks P; Dogan N; Koscielniak E; Schäfer BW
    Oncogene; 2016 Apr; 35(16):2020-30. PubMed ID: 26189795
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma.
    Zibat A; Missiaglia E; Rosenberger A; Pritchard-Jones K; Shipley J; Hahn H; Fulda S
    Oncogene; 2010 Dec; 29(48):6323-30. PubMed ID: 20818440
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma.
    Ignatius MS; Hayes MN; Lobbardi R; Chen EY; McCarthy KM; Sreenivas P; Motala Z; Durbin AD; Molodtsov A; Reeder S; Jin A; Sindiri S; Beleyea BC; Bhere D; Alexander MS; Shah K; Keller C; Linardic CM; Nielsen PG; Malkin D; Khan J; Langenau DM
    Cell Rep; 2017 Jun; 19(11):2304-2318. PubMed ID: 28614716
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis.
    Srivastava RK; Kaylani SZ; Edrees N; Li C; Talwelkar SS; Xu J; Palle K; Pressey JG; Athar M
    Oncotarget; 2014 Dec; 5(23):12151-65. PubMed ID: 25432075
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma.
    Chen EY; DeRan MT; Ignatius MS; Grandinetti KB; Clagg R; McCarthy KM; Lobbardi RM; Brockmann J; Keller C; Wu X; Langenau DM
    Proc Natl Acad Sci U S A; 2014 Apr; 111(14):5349-54. PubMed ID: 24706870
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Novel Notch-YAP Circuit Drives Stemness and Tumorigenesis in Embryonal Rhabdomyosarcoma.
    Slemmons KK; Crose LES; Riedel S; Sushnitha M; Belyea B; Linardic CM
    Mol Cancer Res; 2017 Dec; 15(12):1777-1791. PubMed ID: 28923841
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma.
    Graab U; Hahn H; Fulda S
    Oncotarget; 2015 Apr; 6(11):8722-35. PubMed ID: 25749378
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embryonal rhabdomyosarcoma cells.
    Megiorni F; Gravina GL; Camero S; Ceccarelli S; Del Fattore A; Desiderio V; Papaccio F; McDowell HP; Shukla R; Pizzuti A; Beirinckx F; Pujuguet P; Saniere L; der Aar EV; Maggio R; De Felice F; Marchese C; Dominici C; Tombolini V; Festuccia C; Marampon F
    J Hematol Oncol; 2017 Oct; 10(1):161. PubMed ID: 28985758
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells.
    Santini R; Vinci MC; Pandolfi S; Penachioni JY; Montagnani V; Olivito B; Gattai R; Pimpinelli N; Gerlini G; Borgognoni L; Stecca B
    Stem Cells; 2012 Sep; 30(9):1808-18. PubMed ID: 22730244
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A mouse model of rhabdomyosarcoma originating from the adipocyte lineage.
    Hatley ME; Tang W; Garcia MR; Finkelstein D; Millay DP; Liu N; Graff J; Galindo RL; Olson EN
    Cancer Cell; 2012 Oct; 22(4):536-46. PubMed ID: 23079662
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hedgehog/Patched-associated rhabdomyosarcoma formation from delta1-expressing mesodermal cells.
    Nitzki F; Cuvelier N; Dräger J; Schneider A; Braun T; Hahn H
    Oncogene; 2016 Jun; 35(22):2923-31. PubMed ID: 26387541
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Simultaneous targeting of insulin-like growth factor-1 receptor and anaplastic lymphoma kinase in embryonal and alveolar rhabdomyosarcoma: a rational choice.
    van Gaal JC; Roeffen MH; Flucke UE; van der Laak JA; van der Heijden G; de Bont ES; Suurmeijer AJ; Versleijen-Jonkers YM; van der Graaf WT
    Eur J Cancer; 2013 Nov; 49(16):3462-70. PubMed ID: 23867124
    [TBL] [Abstract][Full Text] [Related]  

  • 13. c-Myb regulates tumorigenic potential of embryonal rhabdomyosarcoma cells.
    Kaspar P; Prochazka J; Efenberkova M; Juhasz A; Novosadova V; Sedlacek R
    Sci Rep; 2019 Apr; 9(1):6342. PubMed ID: 31004084
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Repurposing of posaconazole as a hedgehog/SMO signaling inhibitor for embryonal rhabdomyosarcoma therapy.
    Sun J; Lin W; Li C; Ueki H; Xue R; Sadahira T; Hu H; Wada K; Li N; Liu C; Araki M; Xu A; Huang P
    Am J Cancer Res; 2021; 11(9):4528-4540. PubMed ID: 34659903
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LncRNA-Hh Strengthen Cancer Stem Cells Generation in Twist-Positive Breast Cancer via Activation of Hedgehog Signaling Pathway.
    Zhou M; Hou Y; Yang G; Zhang H; Tu G; Du YE; Wen S; Xu L; Tang X; Tang S; Yang L; Cui X; Liu M
    Stem Cells; 2016 Jan; 34(1):55-66. PubMed ID: 26418365
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer.
    Bora-Singhal N; Perumal D; Nguyen J; Chellappan S
    Neoplasia; 2015 Jul; 17(7):538-51. PubMed ID: 26297432
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma.
    Almazán-Moga A; Zarzosa P; Vidal I; Molist C; Giralt I; Navarro N; Soriano A; Segura MF; Alfranca A; Garcia-Castro J; Sánchez de Toledo J; Roma J; Gallego S
    Stem Cells Int; 2017; 2017():7507380. PubMed ID: 28243259
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma.
    Hayes MN; McCarthy K; Jin A; Oliveira ML; Iyer S; Garcia SP; Sindiri S; Gryder B; Motala Z; Nielsen GP; Borg JP; van de Rijn M; Malkin D; Khan J; Ignatius MS; Langenau DM
    Cell Stem Cell; 2018 Mar; 22(3):414-427.e6. PubMed ID: 29499154
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reduction of human embryonal rhabdomyosarcoma tumor growth by inhibition of the hedgehog signaling pathway.
    Tostar U; Toftgård R; Zaphiropoulos PG; Shimokawa T
    Genes Cancer; 2010 Sep; 1(9):941-51. PubMed ID: 21779473
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interfering with Hedgehog Pathway: New Avenues for Targeted Therapy in Rhabdomyosarcoma.
    Manzella G; Schäfer BW
    Curr Drug Targets; 2016; 17(11):1228-34. PubMed ID: 25944015
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.