BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

572 related articles for article (PubMed ID: 26199860)

  • 1. Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites.
    Engel JA; Jones AJ; Avery VM; Sumanadasa SD; Ng SS; Fairlie DP; Skinner-Adams T; Andrews KT
    Int J Parasitol Drugs Drug Resist; 2015 Dec; 5(3):117-26. PubMed ID: 26199860
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth.
    Chua MJ; Arnold MS; Xu W; Lancelot J; Lamotte S; Späth GF; Prina E; Pierce RJ; Fairlie DP; Skinner-Adams TS; Andrews KT
    Int J Parasitol Drugs Drug Resist; 2017 Apr; 7(1):42-50. PubMed ID: 28107750
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and Synthesis of Novel Anti-Plasmodial Histone Deacetylase Inhibitors Containing an Alkoxyamide Connecting Unit.
    Alves Avelar LA; Held J; Engel JA; Sureechatchaiyan P; Hansen FK; Hamacher A; Kassack MU; Mordmüller B; Andrews KT; Kurz T
    Arch Pharm (Weinheim); 2017 Apr; 350(3-4):. PubMed ID: 28317157
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages.
    Hansen FK; Sumanadasa SD; Stenzel K; Duffy S; Meister S; Marek L; Schmetter R; Kuna K; Hamacher A; Mordmüller B; Kassack MU; Winzeler EA; Avery VM; Andrews KT; Kurz T
    Eur J Med Chem; 2014 Jul; 82():204-13. PubMed ID: 24904967
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In silico identification of inhibitors against Plasmodium falciparum histone deacetylase 1 (PfHDAC-1).
    Kumar A; Dhar SK; Subbarao N
    J Mol Model; 2018 Aug; 24(9):232. PubMed ID: 30109440
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and Synthesis of Terephthalic Acid-Based Histone Deacetylase Inhibitors with Dual-Stage Anti-Plasmodium Activity.
    Stenzel K; Chua MJ; Duffy S; Antonova-Koch Y; Meister S; Hamacher A; Kassack MU; Winzeler E; Avery VM; Kurz T; Andrews KT; Hansen FK
    ChemMedChem; 2017 Oct; 12(19):1627-1636. PubMed ID: 28812327
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.
    Trenholme K; Marek L; Duffy S; Pradel G; Fisher G; Hansen FK; Skinner-Adams TS; Butterworth A; Ngwa CJ; Moecking J; Goodman CD; McFadden GI; Sumanadasa SD; Fairlie DP; Avery VM; Kurz T; Andrews KT
    Antimicrob Agents Chemother; 2014 Jul; 58(7):3666-78. PubMed ID: 24733477
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activity of alkoxyamide-based histone deacetylase inhibitors against Plasmodium falciparum malaria parasites.
    Dawood WA; Fisher GM; Kinnen FJM; Anzenhofer C; Skinner-Adams T; Alves Avelar L; Asfaha Y; Kurz T; Andrews KT
    Exp Parasitol; 2024 Mar; 258():108716. PubMed ID: 38340779
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ex vivo activity of histone deacetylase inhibitors against multidrug-resistant clinical isolates of Plasmodium falciparum and P. vivax.
    Marfurt J; Chalfein F; Prayoga P; Wabiser F; Kenangalem E; Piera KA; Fairlie DP; Tjitra E; Anstey NM; Andrews KT; Price RN
    Antimicrob Agents Chemother; 2011 Mar; 55(3):961-6. PubMed ID: 21135175
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Antimalarial activity of the anticancer histone deacetylase inhibitor SB939.
    Sumanadasa SD; Goodman CD; Lucke AJ; Skinner-Adams T; Sahama I; Haque A; Do TA; McFadden GI; Fairlie DP; Andrews KT
    Antimicrob Agents Chemother; 2012 Jul; 56(7):3849-56. PubMed ID: 22508312
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, antimalarial properties, and SAR studies of alkoxyurea-based HDAC inhibitors.
    Hansen FK; Skinner-Adams TS; Duffy S; Marek L; Sumanadasa SD; Kuna K; Held J; Avery VM; Andrews KT; Kurz T
    ChemMedChem; 2014 Mar; 9(3):665-70. PubMed ID: 24497437
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of histone deacetylase inhibitors (HDACi) as therapeutic leads for human African trypanosomiasis (HAT).
    Carrillo AK; Guiguemde WA; Guy RK
    Bioorg Med Chem; 2015 Aug; 23(16):5151-5. PubMed ID: 25637120
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An ELISA method to assess HDAC inhibitor-induced alterations to P. falciparum histone lysine acetylation.
    Hesping E; Skinner-Adams TS; Fisher GM; Kurz T; Andrews KT
    Int J Parasitol Drugs Drug Resist; 2020 Dec; 14():249-256. PubMed ID: 33279862
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathway.
    Fletcher S; Lucantoni L; Sykes ML; Jones AJ; Holleran JP; Saliba KJ; Avery VM
    Parasit Vectors; 2016 Nov; 9(1):589. PubMed ID: 27855724
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antiprotozoal and cytotoxic screening of 45 plant extracts from Democratic Republic of Congo.
    Mesia GK; Tona GL; Nanga TH; Cimanga RK; Apers S; Cos P; Maes L; Pieters L; Vlietinck AJ
    J Ethnopharmacol; 2008 Feb; 115(3):409-15. PubMed ID: 18068320
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice.
    Chua MJ; Tng J; Hesping E; Fisher GM; Goodman CD; Skinner-Adams T; Do D; Lucke AJ; Reid RC; Fairlie DP; Andrews KT
    Int J Parasitol Drugs Drug Resist; 2021 Dec; 17():118-127. PubMed ID: 34560571
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histone deacetylase inhibitors with high in vitro activities against Plasmodium falciparum isolates collected from Gabonese children and adults.
    Koehne E; Kreidenweiss A; Zoleko Manego R; McCall M; Mombo-Ngoma G; Mackwitz MKW; Hansen FK; Held J
    Sci Rep; 2019 Nov; 9(1):17336. PubMed ID: 31758015
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite.
    Giannini G; Battistuzzi G; Vignola D
    Bioorg Med Chem Lett; 2015 Feb; 25(3):459-61. PubMed ID: 25563890
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitors.
    Andrews KT; Gupta AP; Tran TN; Fairlie DP; Gobert GN; Bozdech Z
    PLoS One; 2012; 7(2):e31847. PubMed ID: 22384084
    [TBL] [Abstract][Full Text] [Related]  

  • 20. One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites.
    Diedrich D; Stenzel K; Hesping E; Antonova-Koch Y; Gebru T; Duffy S; Fisher G; Schöler A; Meister S; Kurz T; Avery VM; Winzeler EA; Held J; Andrews KT; Hansen FK
    Eur J Med Chem; 2018 Oct; 158():801-813. PubMed ID: 30245402
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.