BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

348 related articles for article (PubMed ID: 26212886)

  • 1. Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis.
    Mkrtchyan G; Aleshin V; Parkhomenko Y; Kaehne T; Di Salvo ML; Parroni A; Contestabile R; Vovk A; Bettendorff L; Bunik V
    Sci Rep; 2015 Jul; 5():12583. PubMed ID: 26212886
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thiamin diphosphate in biological chemistry: new aspects of thiamin metabolism, especially triphosphate derivatives acting other than as cofactors.
    Bettendorff L; Wins P
    FEBS J; 2009 Jun; 276(11):2917-25. PubMed ID: 19490098
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thiamin diphosphate-dependent enzymes: from enzymology to metabolic regulation, drug design and disease models.
    Bunik VI; Tylicki A; Lukashev NV
    FEBS J; 2013 Dec; 280(24):6412-42. PubMed ID: 24004353
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation.
    Hohmann S; Meacock PA
    Biochim Biophys Acta; 1998 Jun; 1385(2):201-19. PubMed ID: 9655908
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Daytime Dependence of the Activity of the Rat Brain Pyruvate Dehydrogenase Corresponds to the Mitochondrial Sirtuin 3 Level and Acetylation of Brain Proteins, All Regulated by Thiamine Administration Decreasing Phosphorylation of PDHA Ser293.
    Aleshin VA; Artiukhov AV; Kaehne T; Graf AV; Bunik VI
    Int J Mol Sci; 2021 Jul; 22(15):. PubMed ID: 34360775
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of Malate Dehydrogenases and Glutamate Dehydrogenase of Mammalian Brain by Thiamine in vitro and in vivo.
    Mezhenska OA; Aleshin VA; Kaehne T; Artiukhov AV; Bunik VI
    Biochemistry (Mosc); 2020 Jan; 85(1):27-39. PubMed ID: 32079515
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tetrahedral intermediates in thiamin diphosphate-dependent decarboxylations exist as a 1',4'-imino tautomeric form of the coenzyme, unlike the michaelis complex or the free coenzyme.
    Nemeria N; Baykal A; Joseph E; Zhang S; Yan Y; Furey W; Jordan F
    Biochemistry; 2004 Jun; 43(21):6565-75. PubMed ID: 15157089
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanisms of Non-coenzyme Action of Thiamine: Protein Targets and Medical Significance.
    Aleshin VA; Mkrtchyan GV; Bunik VI
    Biochemistry (Mosc); 2019 Aug; 84(8):829-850. PubMed ID: 31522667
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of charge transfer transitions related to thiamin-bound intermediates on enzymes provides a plethora of signatures useful in mechanistic studies.
    Patel H; Nemeria NS; Andrews FH; McLeish MJ; Jordan F
    Biochemistry; 2014 Apr; 53(13):2145-52. PubMed ID: 24628377
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thiamin diphosphate in biological chemistry: applications in biocatalysis, coenzyme analogues as mechanistic probes and natural derivatives of thiamin.
    Tittmann K
    FEBS J; 2009 Jun; 276(11):2893. PubMed ID: 19490095
    [No Abstract]   [Full Text] [Related]  

  • 11. Structural determinants of enzyme binding affinity: the E1 component of pyruvate dehydrogenase from Escherichia coli in complex with the inhibitor thiamin thiazolone diphosphate.
    Arjunan P; Chandrasekhar K; Sax M; Brunskill A; Nemeria N; Jordan F; Furey W
    Biochemistry; 2004 Mar; 43(9):2405-11. PubMed ID: 14992577
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Arabidopsis thiamin-deficient mutant pale green1 lacks thiamin monophosphate phosphatase of the vitamin B
    Hsieh WY; Liao JC; Wang HT; Hung TH; Tseng CC; Chung TY; Hsieh MH
    Plant J; 2017 Jul; 91(1):145-157. PubMed ID: 28346710
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin.
    Nemeria NS; Shome B; DeColli AA; Heflin K; Begley TP; Meyers CF; Jordan F
    Biochemistry; 2016 Feb; 55(7):1135-48. PubMed ID: 26813608
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thiamin diphosphate in biological chemistry: analogues of thiamin diphosphate in studies of enzymes and riboswitches.
    Agyei-Owusu K; Leeper FJ
    FEBS J; 2009 Jun; 276(11):2905-16. PubMed ID: 19490097
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design of thiamine analogues for inhibition of thiamine diphosphate (ThDP)-dependent enzymes: Systematic investigation through Scaffold-Hopping and C2-Functionalisation.
    Chan AHY; Ho TCS; Irfan R; Hamid RAA; Rudge ES; Iqbal A; Turner A; Hirsch AKH; Leeper FJ
    Bioorg Chem; 2023 Sep; 138():106602. PubMed ID: 37201323
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Influence of allosteric regulators on individual steps in the reaction catalyzed by Mycobacterium tuberculosis 2-hydroxy-3-oxoadipate synthase.
    Balakrishnan A; Jordan F; Nathan CF
    J Biol Chem; 2013 Jul; 288(30):21688-702. PubMed ID: 23760263
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intermediates and transition states in thiamin diphosphate-dependent decarboxylases. A kinetic and NMR study on wild-type indolepyruvate decarboxylase and variants using indolepyruvate, benzoylformate, and pyruvate as substrates.
    Schütz A; Golbik R; König S; Hübner G; Tittmann K
    Biochemistry; 2005 Apr; 44(16):6164-79. PubMed ID: 15835904
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism.
    Goyer A; Hasnain G; Frelin O; Ralat MA; Gregory JF; Hanson AD
    Biochem J; 2013 Sep; 454(3):533-42. PubMed ID: 23834287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thiamin nutrition and catalysis-induced instability of thiamin diphosphate.
    McCourt JA; Nixon PF; Duggleby RG
    Br J Nutr; 2006 Oct; 96(4):636-8. PubMed ID: 17010220
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Communication between thiamin cofactors in the Escherichia coli pyruvate dehydrogenase complex E1 component active centers: evidence for a "direct pathway" between the 4'-aminopyrimidine N1' atoms.
    Nemeria NS; Arjunan P; Chandrasekhar K; Mossad M; Tittmann K; Furey W; Jordan F
    J Biol Chem; 2010 Apr; 285(15):11197-209. PubMed ID: 20106967
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.