BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 26219303)

  • 1. Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner.
    Mochizuki-Kashio M; Aoyama K; Sashida G; Oshima M; Tomioka T; Muto T; Wang C; Iwama A
    Blood; 2015 Sep; 126(10):1172-83. PubMed ID: 26219303
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.
    Muto T; Sashida G; Oshima M; Wendt GR; Mochizuki-Kashio M; Nagata Y; Sanada M; Miyagi S; Saraya A; Kamio A; Nagae G; Nakaseko C; Yokote K; Shimoda K; Koseki H; Suzuki Y; Sugano S; Aburatani H; Ogawa S; Iwama A
    J Exp Med; 2013 Nov; 210(12):2627-39. PubMed ID: 24218139
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PRC2 insufficiency causes p53-dependent dyserythropoiesis in myelodysplastic syndrome.
    Aoyama K; Shinoda D; Suzuki E; Nakajima-Takagi Y; Oshima M; Koide S; Rizq O; Si S; Tara S; Sashida G; Iwama A
    Leukemia; 2021 Apr; 35(4):1156-1165. PubMed ID: 32820269
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells.
    Mochizuki-Kashio M; Mishima Y; Miyagi S; Negishi M; Saraya A; Konuma T; Shinga J; Koseki H; Iwama A
    Blood; 2011 Dec; 118(25):6553-61. PubMed ID: 22042701
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia.
    Xu B; On DM; Ma A; Parton T; Konze KD; Pattenden SG; Allison DF; Cai L; Rockowitz S; Liu S; Liu Y; Li F; Vedadi M; Frye SV; Garcia BA; Zheng D; Jin J; Wang GG
    Blood; 2015 Jan; 125(2):346-57. PubMed ID: 25395428
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ezh1 Targets Bivalent Genes to Maintain Self-Renewing Stem Cells in Ezh2-Insufficient Myelodysplastic Syndrome.
    Aoyama K; Oshima M; Koide S; Suzuki E; Mochizuki-Kashio M; Kato Y; Tara S; Shinoda D; Hiura N; Nakajima-Takagi Y; Sashida G; Iwama A
    iScience; 2018 Nov; 9():161-174. PubMed ID: 30396150
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Polycomb Repressive Complex 2 Proteins EZH1 and EZH2 Regulate Timing of Postnatal Hepatocyte Maturation and Fibrosis by Repressing Genes With Euchromatic Promoters in Mice.
    Grindheim JM; Nicetto D; Donahue G; Zaret KS
    Gastroenterology; 2019 May; 156(6):1834-1848. PubMed ID: 30689973
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ezh2 regulates the Lin28/let-7 pathway to restrict activation of fetal gene signature in adult hematopoietic stem cells.
    Oshima M; Hasegawa N; Mochizuki-Kashio M; Muto T; Miyagi S; Koide S; Yabata S; Wendt GR; Saraya A; Wang C; Shimoda K; Suzuki Y; Iwama A
    Exp Hematol; 2016 Apr; 44(4):282-96.e3. PubMed ID: 26773568
    [TBL] [Abstract][Full Text] [Related]  

  • 9. EZH1 in germ cells safeguards the function of PRC2 during spermatogenesis.
    Mu W; Starmer J; Shibata Y; Yee D; Magnuson T
    Dev Biol; 2017 Apr; 424(2):198-207. PubMed ID: 28254491
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2.
    Soto RA; Najia MAT; Hachimi M; Frame JM; Yette GA; Lummertz da Rocha E; Stankunas K; Daley GQ; North TE
    Stem Cell Reports; 2021 Jul; 16(7):1718-1734. PubMed ID: 34143974
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oncogenic roles of enhancer of zeste homolog 1/2 in hematological malignancies.
    Nakagawa M; Kitabayashi I
    Cancer Sci; 2018 Aug; 109(8):2342-2348. PubMed ID: 29845708
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis.
    Lee SC; Miller S; Hyland C; Kauppi M; Lebois M; Di Rago L; Metcalf D; Kinkel SA; Josefsson EC; Blewitt ME; Majewski IJ; Alexander WS
    Blood; 2015 Jul; 126(2):167-75. PubMed ID: 26036803
    [TBL] [Abstract][Full Text] [Related]  

  • 13. EZH2 in normal hematopoiesis and hematological malignancies.
    Herviou L; Cavalli G; Cartron G; Klein B; Moreaux J
    Oncotarget; 2016 Jan; 7(3):2284-96. PubMed ID: 26497210
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons.
    Henriquez B; Bustos FJ; Aguilar R; Becerra A; Simon F; Montecino M; van Zundert B
    Mol Cell Neurosci; 2013 Nov; 57():130-43. PubMed ID: 23932971
    [TBL] [Abstract][Full Text] [Related]  

  • 15. EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer.
    Wassef M; Luscan A; Aflaki S; Zielinski D; Jansen PWTC; Baymaz HI; Battistella A; Kersouani C; Servant N; Wallace MR; Romero P; Kosmider O; Just PA; Hivelin M; Jacques S; Vincent-Salomon A; Vermeulen M; Vidaud M; Pasmant E; Margueron R
    Proc Natl Acad Sci U S A; 2019 Mar; 116(13):6075-6080. PubMed ID: 30867289
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dual Inhibition of EZH2 and EZH1 Sensitizes PRC2-Dependent Tumors to Proteasome Inhibition.
    Rizq O; Mimura N; Oshima M; Saraya A; Koide S; Kato Y; Aoyama K; Nakajima-Takagi Y; Wang C; Chiba T; Ma A; Jin J; Iseki T; Nakaseko C; Iwama A
    Clin Cancer Res; 2017 Aug; 23(16):4817-4830. PubMed ID: 28490465
    [No Abstract]   [Full Text] [Related]  

  • 17. Impact of combinatorial dysfunctions of Tet2 and Ezh2 on the epigenome in the pathogenesis of myelodysplastic syndrome.
    Hasegawa N; Oshima M; Sashida G; Matsui H; Koide S; Saraya A; Wang C; Muto T; Takane K; Kaneda A; Shimoda K; Nakaseko C; Yokote K; Iwama A
    Leukemia; 2017 Apr; 31(4):861-871. PubMed ID: 27694924
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.
    Son J; Shen SS; Margueron R; Reinberg D
    Genes Dev; 2013 Dec; 27(24):2663-77. PubMed ID: 24352422
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Epigenetic aberrations in adult T-cell leukemia/lymphoma and development of a novel EZH1/2 inhibitor].
    Yamagishi M
    Rinsho Ketsueki; 2018; 59(4):432-438. PubMed ID: 29743404
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multiple mechanisms deregulate EZH2 and histone H3 lysine 27 epigenetic changes in myeloid malignancies.
    Khan SN; Jankowska AM; Mahfouz R; Dunbar AJ; Sugimoto Y; Hosono N; Hu Z; Cheriyath V; Vatolin S; Przychodzen B; Reu FJ; Saunthararajah Y; O'Keefe C; Sekeres MA; List AF; Moliterno AR; McDevitt MA; Maciejewski JP; Makishima H
    Leukemia; 2013 Jun; 27(6):1301-9. PubMed ID: 23486531
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.