BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

448 related articles for article (PubMed ID: 26219309)

  • 1. Rapamycin alleviates pathogenesis of a new Drosophila model of ALS-TDP.
    Cheng CW; Lin MJ; Shen CK
    J Neurogenet; 2015; 29(2-3):59-68. PubMed ID: 26219309
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neuronal function and dysfunction of Drosophila dTDP.
    Lin MJ; Cheng CW; Shen CK
    PLoS One; 2011; 6(6):e20371. PubMed ID: 21673800
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies.
    Miguel L; Frébourg T; Campion D; Lecourtois M
    Neurobiol Dis; 2011 Feb; 41(2):398-406. PubMed ID: 20951205
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel Drosophila model of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects.
    Langellotti S; Romano V; Romano G; Klima R; Feiguin F; Cragnaz L; Romano M; Baralle FE
    Dis Model Mech; 2016 Jun; 9(6):659-69. PubMed ID: 27101846
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An age-related reduction of brain TBPH/TDP-43 levels precedes the onset of locomotion defects in a Drosophila ALS model.
    Cragnaz L; Klima R; De Conti L; Romano G; Feiguin F; Buratti E; Baralle M; Baralle FE
    Neuroscience; 2015 Dec; 311():415-21. PubMed ID: 26518462
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila.
    Li Z; Lu Y; Xu XL; Gao FB
    Hum Mol Genet; 2013 Jan; 22(2):218-25. PubMed ID: 23042786
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy.
    Ihara R; Matsukawa K; Nagata Y; Kunugi H; Tsuji S; Chihara T; Kuranaga E; Miura M; Wakabayashi T; Hashimoto T; Iwatsubo T
    Hum Mol Genet; 2013 Nov; 22(22):4474-84. PubMed ID: 23804749
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43.
    Wang IF; Guo BS; Liu YC; Wu CC; Yang CH; Tsai KJ; Shen CK
    Proc Natl Acad Sci U S A; 2012 Sep; 109(37):15024-9. PubMed ID: 22932872
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching.
    Lu Y; Ferris J; Gao FB
    Mol Brain; 2009 Sep; 2():30. PubMed ID: 19781077
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lower motor neuron involvement in TAR DNA-binding protein of 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Riku Y; Watanabe H; Yoshida M; Tatsumi S; Mimuro M; Iwasaki Y; Katsuno M; Iguchi Y; Masuda M; Senda J; Ishigaki S; Udagawa T; Sobue G
    JAMA Neurol; 2014 Feb; 71(2):172-9. PubMed ID: 24378564
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TDP-43-mediated neurodegeneration: towards a loss-of-function hypothesis?
    Vanden Broeck L; Callaerts P; Dermaut B
    Trends Mol Med; 2014 Feb; 20(2):66-71. PubMed ID: 24355761
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam.
    Geser F; Winton MJ; Kwong LK; Xu Y; Xie SX; Igaz LM; Garruto RM; Perl DP; Galasko D; Lee VM; Trojanowski JQ
    Acta Neuropathol; 2008 Jan; 115(1):133-45. PubMed ID: 17713769
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS.
    Krug L; Chatterjee N; Borges-Monroy R; Hearn S; Liao WW; Morrill K; Prazak L; Rozhkov N; Theodorou D; Hammell M; Dubnau J
    PLoS Genet; 2017 Mar; 13(3):e1006635. PubMed ID: 28301478
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD.
    Diaper DC; Adachi Y; Lazarou L; Greenstein M; Simoes FA; Di Domenico A; Solomon DA; Lowe S; Alsubaie R; Cheng D; Buckley S; Humphrey DM; Shaw CE; Hirth F
    Hum Mol Genet; 2013 Oct; 22(19):3883-93. PubMed ID: 23727833
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A microfluidic approach to rescue ALS motor neuron degeneration using rapamycin.
    Chennampally P; Sayed-Zahid A; Soundararajan P; Sharp J; Cox GA; Collins SD; Smith RL
    Sci Rep; 2021 Sep; 11(1):18168. PubMed ID: 34518579
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small Molecule Targeting TDP-43's RNA Recognition Motifs Reduces Locomotor Defects in a
    François-Moutal L; Felemban R; Scott DD; Sayegh MR; Miranda VG; Perez-Miller S; Khanna R; Gokhale V; Zarnescu DC; Khanna M
    ACS Chem Biol; 2019 Sep; 14(9):2006-2013. PubMed ID: 31241884
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Traumatic injury induces stress granule formation and enhances motor dysfunctions in ALS/FTD models.
    Anderson EN; Gochenaur L; Singh A; Grant R; Patel K; Watkins S; Wu JY; Pandey UB
    Hum Mol Genet; 2018 Apr; 27(8):1366-1381. PubMed ID: 29432563
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PPAR gamma activation is neuroprotective in a Drosophila model of ALS based on TDP-43.
    Joardar A; Menzl J; Podolsky TC; Manzo E; Estes PS; Ashford S; Zarnescu DC
    Hum Mol Genet; 2015 Mar; 24(6):1741-54. PubMed ID: 25432537
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis.
    Estes PS; Daniel SG; McCallum AP; Boehringer AV; Sukhina AS; Zwick RA; Zarnescu DC
    Dis Model Mech; 2013 May; 6(3):721-33. PubMed ID: 23471911
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS.
    Manzo E; Lorenzini I; Barrameda D; O'Conner AG; Barrows JM; Starr A; Kovalik T; Rabichow BE; Lehmkuhl EM; Shreiner DD; Joardar A; Liévens JC; Bowser R; Sattler R; Zarnescu DC
    Elife; 2019 Jun; 8():. PubMed ID: 31180318
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.