BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

87 related articles for article (PubMed ID: 26225720)

  • 1. Enhancing Bulge Stabilization through Linear Extension of C8-Aryl-Guanine Adducts to Promote Polymerase Blockage or Strand Realignment to Produce a C:C Mismatch.
    Sproviero M; Verwey AM; Witham AA; Manderville RA; Sharma P; Wetmore SD
    Chem Res Toxicol; 2015 Aug; 28(8):1647-58. PubMed ID: 26225720
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chlorine functionalization of a model phenolic C8-guanine adduct increases conformational rigidity and blocks extension by a Y-family DNA polymerase.
    Witham AA; Verwey AM; Sproviero M; Manderville RA; Sharma P; Wetmore SD
    Chem Res Toxicol; 2015 Jun; 28(6):1346-56. PubMed ID: 26004422
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and biochemical impact of C8-aryl-guanine adducts within the NarI recognition DNA sequence: influence of aryl ring size on targeted and semi-targeted mutagenicity.
    Sproviero M; Verwey AM; Rankin KM; Witham AA; Soldatov DV; Manderville RA; Fekry MI; Sturla SJ; Sharma P; Wetmore SD
    Nucleic Acids Res; 2014 Dec; 42(21):13405-21. PubMed ID: 25361967
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conformational Preference and Fluorescence Response of a C-Linked C8-Biphenyl-Guanine Lesion in the NarI Mutational Hotspot: Evidence for Enhanced Syn Adduct Formation.
    Berger FD; Sturla SJ; Kung RW; Montina T; Wetmore SD; Manderville RA
    Chem Res Toxicol; 2018 Jan; 31(1):37-47. PubMed ID: 29186656
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural influence of C8-phenoxy-guanine in the NarI recognition DNA sequence.
    Kuska MS; Witham AA; Sproviero M; Manderville RA; Majdi Yazdi M; Sharma P; Wetmore SD
    Chem Res Toxicol; 2013 Sep; 26(9):1397-408. PubMed ID: 23984847
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Adduct Fluorescence as a Tool to Decipher Sequence Impact on Frameshift Mutations Mediated by a C-Linked C8-Biphenyl-Guanine Lesion.
    Berger FD; Manderville RA; Sturla SJ
    Chem Res Toxicol; 2019 Apr; 32(4):784-791. PubMed ID: 30785283
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Understanding the Mutagenicity of O-Linked and C-Linked Guanine DNA Adducts: A Combined Experimental and Computational Approach.
    Manderville RA; Wetmore SD
    Chem Res Toxicol; 2017 Jan; 30(1):177-188. PubMed ID: 27768845
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutagenicity of Ochratoxin A: Role for a Carbon-Linked C8-Deoxyguanosine Adduct?
    Manderville RA; Wetmore SD
    J Agric Food Chem; 2017 Aug; 65(33):7097-7105. PubMed ID: 28830149
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Solution structure of the aminofluorene [AF]-external conformer of the anti-[AF]-C8-dG adduct opposite dC in a DNA duplex.
    Mao B; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1998 Jan; 37(1):95-106. PubMed ID: 9425029
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Solution structure of the aminofluorene-intercalated conformer of the syn [AF]-C8-dG adduct opposite a--2 deletion site in the NarI hot spot sequence context.
    Mao B; Gorin A; Gu Z; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1997 Nov; 36(47):14479-90. PubMed ID: 9398167
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Translesion synthesis past the C8- and N2-deoxyguanosine adducts of the dietary mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the NarI recognition sequence by prokaryotic DNA polymerases.
    Stover JS; Chowdhury G; Zang H; Guengerich FP; Rizzo CJ
    Chem Res Toxicol; 2006 Nov; 19(11):1506-17. PubMed ID: 17112239
    [TBL] [Abstract][Full Text] [Related]  

  • 12. C8-heteroaryl-2'-deoxyguanosine adducts as conformational fluorescent probes in the NarI recognition sequence.
    Rankin KM; Sproviero M; Rankin K; Sharma P; Wetmore SD; Manderville RA
    J Org Chem; 2012 Dec; 77(23):10498-508. PubMed ID: 23171213
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Solution structure of the aminofluorene-stacked conformer of the syn [AF]-C8-dG adduct positioned at a template-primer junction.
    Mao B; Gu Z; Gorin A; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1997 Nov; 36(47):14491-501. PubMed ID: 9398168
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fluorescent C-linked C8-aryl-guanine probe for distinguishing syn from anti structures in duplex DNA.
    Manderville RA; Omumi A; Rankin née Schlitt KM; Wilson KA; Millen AL; Wetmore SD
    Chem Res Toxicol; 2012 Jun; 25(6):1271-82. PubMed ID: 22667322
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Influence of the linkage type and functional groups in the carcinogenic moiety on the conformational preferences of damaged DNA: structural and energetic characterization of carbon- and oxygen-linked C(8)-phenolic-guanine adducts.
    Sharma P; Majdi Yazdi M; Merriman A; Manderville RA; Wetmore SD
    Chem Res Toxicol; 2015 Apr; 28(4):782-96. PubMed ID: 25658653
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of an Unusual Tetracyclic Deoxyguanosine Adduct: Implications for Frameshift Mutagenicity of
    Manning TW; Al-Abdul-Wahid MS; Manderville RA; Josephy PD; Kung RW; Wetmore SD
    Chem Res Toxicol; 2020 Feb; 33(2):584-593. PubMed ID: 31885260
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells.
    Yasui M; Dong H; Bonala RR; Suzuki N; Ohmori H; Hanaoka F; Johnson F; Grollman AP; Shibutani S
    Biochemistry; 2004 Nov; 43(47):15005-13. PubMed ID: 15554708
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fluorescent properties and conformational preferences of C-linked phenolic-DNA adducts.
    Omumi A; Millen AL; Wetmore SD; Manderville RA
    Chem Res Toxicol; 2011 Oct; 24(10):1694-709. PubMed ID: 21905681
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular Modeling of the Major DNA Adduct Formed from Food Mutagen Ochratoxin A in NarI Two-Base Deletion Duplexes: Impact of Sequence Context and Adduct Ionization on Conformational Preference and Mutagenicity.
    Kathuria P; Sharma P; Manderville RA; Wetmore SD
    Chem Res Toxicol; 2017 Aug; 30(8):1582-1591. PubMed ID: 28719194
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of Guanine Adduct Size, Shape, and Linker Type on the Conformation of Adducted DNA: A DFT and Molecular Dynamics Study.
    Jeong YER; Kung RW; Bykowski J; Deak TK; Wetmore SD
    J Phys Chem B; 2023 Oct; 127(42):9035-9049. PubMed ID: 37831812
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.