These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Evaluation of structural effects on 5-HT(2A) receptor antagonism by aporphines: identification of a new aporphine with 5-HT(2A) antagonist activity. Ponnala S; Gonzales J; Kapadia N; Navarro HA; Harding WW Bioorg Med Chem Lett; 2014 Apr; 24(7):1664-7. PubMed ID: 24630561 [TBL] [Abstract][Full Text] [Related]
3. New aporphinoid 5-HT2A and α1A antagonists via structural manipulations of nantenine. Chaudhary S; Ponnala S; Legendre O; Gonzales JA; Navarro HA; Harding WW Bioorg Med Chem; 2011 Oct; 19(19):5861-8. PubMed ID: 21900013 [TBL] [Abstract][Full Text] [Related]
4. Synthesis and evaluation of aporphine analogs containing C1 allyl isosteres at the h5-HT(2A) receptor. Ponnala S; Kapadia N; Madapa S; Alberts IL; Harding WW Bioorg Med Chem Lett; 2015 Nov; 25(22):5102-6. PubMed ID: 26475518 [TBL] [Abstract][Full Text] [Related]
5. (+/-)-Nantenine analogs as antagonists at human 5-HT(2A) receptors: C1 and flexible congeners. Chaudhary S; Pecic S; Legendre O; Navarro HA; Harding WW Bioorg Med Chem Lett; 2009 May; 19(9):2530-2. PubMed ID: 19328689 [TBL] [Abstract][Full Text] [Related]
6. Aporphinoid antagonists of 5-HT2A receptors: further evaluation of ring A substituents and the size of ring C. Ponnala S; Kapadia N; Navarro HA; Harding WW Chem Biol Drug Des; 2014 Nov; 84(5):558-66. PubMed ID: 24766771 [TBL] [Abstract][Full Text] [Related]
7. Affinity of aporphines for the human 5-HT2A receptor: insights from homology modeling and molecular docking studies. Pecic S; Makkar P; Chaudhary S; Reddy BV; Navarro HA; Harding WW Bioorg Med Chem; 2010 Aug; 18(15):5562-75. PubMed ID: 20621490 [TBL] [Abstract][Full Text] [Related]
8. New halogenated tris-(phenylalkyl)amines as h5-HT2B receptor ligands. Kapadia N; Ahmed S; Harding WW Bioorg Med Chem Lett; 2016 Jul; 26(14):3216-3219. PubMed ID: 27261181 [TBL] [Abstract][Full Text] [Related]
9. Discovery of novel potent and selective ligands for 5-HT2A receptor with quinazoline scaffold. Deng X; Guo L; Xu L; Zhen X; Yu K; Zhao W; Fu W Bioorg Med Chem Lett; 2015 Sep; 25(18):3970-4. PubMed ID: 26227779 [TBL] [Abstract][Full Text] [Related]
16. Identification of fused bicyclic heterocycles as potent and selective 5-HT(2A) receptor antagonists for the treatment of insomnia. Xiong Y; Ullman B; Choi JS; Cherrier M; Strah-Pleynet S; Decaire M; Feichtinger K; Frazer JM; Yoon WH; Whelan K; Sanabria EK; Grottick AJ; Al-Shamma H; Semple G Bioorg Med Chem Lett; 2012 Mar; 22(5):1870-3. PubMed ID: 22325948 [TBL] [Abstract][Full Text] [Related]
17. S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: I. A mechanistic characterization. Millan MJ; Mannoury la Cour C; Chanrion B; Dupuis DS; Di Cara B; Audinot V; Cussac D; Newman-Tancredi A; Kamal M; Boutin JA; Jockers R; Marin P; Bockaert J; Muller O; Dekeyne A; Lavielle G J Pharmacol Exp Ther; 2012 Mar; 340(3):750-64. PubMed ID: 22178752 [TBL] [Abstract][Full Text] [Related]
18. Structural combination of established 5-HT(2A) receptor ligands: new aspects of the binding mode. Kramer V; Herth MM; Santini MA; Palner M; Knudsen GM; Rösch F Chem Biol Drug Des; 2010 Oct; 76(4):361-6. PubMed ID: 20636331 [TBL] [Abstract][Full Text] [Related]
19. Effects of EGIS-7625, a selective and competitive 5-HT2B receptor antagonist. Kovács A; Gacsályi I; Wellmann J; Schmidt E; Szücs Z; Dubreuil V; Nicolas JP; Boutin J; Bózsing D; Egyed A; Tihanyi K; Spedding M; Szénási G Cardiovasc Drugs Ther; 2003; 17(5-6):427-34. PubMed ID: 15107597 [TBL] [Abstract][Full Text] [Related]
20. Identification of C10 nitrogen-containing aporphines with dopamine D Karki A; Juarez R; Namballa HK; Alberts I; Harding WW Bioorg Med Chem Lett; 2020 Apr; 30(8):127053. PubMed ID: 32107165 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]