331 related articles for article (PubMed ID: 26239802)
1. Meclizine, a pregnane X receptor agonist, is a direct inhibitor and mechanism-based inactivator of human cytochrome P450 3A.
Foo WY; Tay HY; Chan EC; Lau AJ
Biochem Pharmacol; 2015 Oct; 97(3):320-30. PubMed ID: 26239802
[TBL] [Abstract][Full Text] [Related]
2. Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor.
Lau AJ; Yang G; Rajaraman G; Baucom CC; Chang TK
J Pharmacol Exp Ther; 2011 Mar; 336(3):816-26. PubMed ID: 21131266
[TBL] [Abstract][Full Text] [Related]
3. Allosteric activation of midazolam CYP3A5 hydroxylase activity by icotinib - Enhancement by ketoconazole.
Zhuang X; Zhang T; Yue S; Wang J; Luo H; Zhang Y; Li Z; Che J; Yang H; Li H; Zhu M; Lu C
Biochem Pharmacol; 2016 Dec; 121():67-77. PubMed ID: 27666601
[TBL] [Abstract][Full Text] [Related]
4. 3,4-methylenedioxymethamphetamine (MDMA) interacts with therapeutic drugs on CYP3A by inhibition of pregnane X receptor (PXR) activation and catalytic enzyme inhibition.
Antolino-Lobo I; Meulenbelt J; Nijmeijer SM; Maas-Bakker RF; Meijerman I; van den Berg M; van Duursen MB
Toxicol Lett; 2011 May; 203(1):82-91. PubMed ID: 21402137
[TBL] [Abstract][Full Text] [Related]
5. Cytochrome P450 3A-dependent metabolism of a potent and selective gamma-aminobutyric acid Aalpha2/3 receptor agonist in vitro: involvement of cytochrome P450 3A5 displaying biphasic kinetics.
Ma B; Polsky-Fisher SL; Vickers S; Cui D; Rodrigues AD
Drug Metab Dispos; 2007 Aug; 35(8):1301-7. PubMed ID: 17460031
[TBL] [Abstract][Full Text] [Related]
6. Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies.
Niwa T; Okamoto A; Narita K; Toyota M; Kato K; Kobayashi K; Sasaki S
Arch Biochem Biophys; 2020 Mar; 682():108283. PubMed ID: 32001245
[TBL] [Abstract][Full Text] [Related]
7. Delineation of the interactions between the chemotherapeutic agent eribulin mesylate (E7389) and human CYP3A4.
Zhang ZY; King BM; Pelletier RD; Wong YN
Cancer Chemother Pharmacol; 2008 Sep; 62(4):707-16. PubMed ID: 18431572
[TBL] [Abstract][Full Text] [Related]
8. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
Butler AM; Murray M
J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
[TBL] [Abstract][Full Text] [Related]
9. alpha-Naphthoflavone acts as activator and reversible or irreversible inhibitor of rabbit microsomal CYP3A6.
Boek-Dohalská L; Hodek P; Sulc M; Stiborová M
Chem Biol Interact; 2001 Oct; 138(1):85-106. PubMed ID: 11640917
[TBL] [Abstract][Full Text] [Related]
10. Efficient substrate screening and inhibitor testing of human CYP4Z1 using permeabilized recombinant fission yeast.
Yan Q; Machalz D; Zöllner A; Sorensen EJ; Wolber G; Bureik M
Biochem Pharmacol; 2017 Dec; 146():174-187. PubMed ID: 28951277
[TBL] [Abstract][Full Text] [Related]
11. Stimulatory and Inhibitory Effects of Steroid Hormones and Human Cytochrome P450 (CYP) 3A Inhibitors on Cortisol 6β-Hydroxylation Catalyzed by CYP3A Subfamilies.
Niwa T; Tani M; Suzuki A; Murakami M
Drug Metab Bioanal Lett; 2023; 16(2):73-80. PubMed ID: 37649294
[TBL] [Abstract][Full Text] [Related]
12. Vitamin E analogues differentially inhibit human cytochrome P450 3A (CYP3A)-mediated oxidative metabolism of lithocholic acid: Impact of δ-tocotrienol on lithocholic acid cytotoxicity.
Wong SY; Teo JSM; Chai SF; Yeap SL; Lau AJ
Toxicology; 2019 Jul; 423():62-74. PubMed ID: 31102695
[TBL] [Abstract][Full Text] [Related]
13. Dual effects of ketoconazole cis-enantiomers on CYP3A4 in human hepatocytes and HepG2 Cells.
Novotná A; Krasulová K; Bartoňková I; Korhoňová M; Bachleda P; Anzenbacher P; Dvořák Z
PLoS One; 2014; 9(10):e111286. PubMed ID: 25343516
[TBL] [Abstract][Full Text] [Related]
14. Quantitative prediction of macrolide drug-drug interaction potential from in vitro studies using testosterone as the human cytochrome P4503A substrate.
Polasek TM; Miners JO
Eur J Clin Pharmacol; 2006 Mar; 62(3):203-8. PubMed ID: 16416302
[TBL] [Abstract][Full Text] [Related]
15. Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism.
Westlind-Johnsson A; Malmebo S; Johansson A; Otter C; Andersson TB; Johansson I; Edwards RJ; Boobis AR; Ingelman-Sundberg M
Drug Metab Dispos; 2003 Jun; 31(6):755-61. PubMed ID: 12756208
[TBL] [Abstract][Full Text] [Related]
16. Inhibition and activation of the human liver microsomal and human cytochrome P450 3A4 metabolism of testosterone by deployment-related chemicals.
Usmani KA; Rose RL; Hodgson E
Drug Metab Dispos; 2003 Apr; 31(4):384-91. PubMed ID: 12642463
[TBL] [Abstract][Full Text] [Related]
17. Selective mechanism-based inactivation of CYP3A4 by CYP3cide (PF-04981517) and its utility as an in vitro tool for delineating the relative roles of CYP3A4 versus CYP3A5 in the metabolism of drugs.
Walsky RL; Obach RS; Hyland R; Kang P; Zhou S; West M; Geoghegan KF; Helal CJ; Walker GS; Goosen TC; Zientek MA
Drug Metab Dispos; 2012 Sep; 40(9):1686-97. PubMed ID: 22645092
[TBL] [Abstract][Full Text] [Related]
18. Mechanism-based inactivation of CYP3A by HIV protease inhibitors.
Ernest CS; Hall SD; Jones DR
J Pharmacol Exp Ther; 2005 Feb; 312(2):583-91. PubMed ID: 15523003
[TBL] [Abstract][Full Text] [Related]
19. Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.
Yamazaki H; Shimada T
Drug Metab Dispos; 1998 Nov; 26(11):1053-7. PubMed ID: 9806945
[TBL] [Abstract][Full Text] [Related]
20. Characterization of the selectivity and mechanism of human cytochrome P450 inhibition by the human immunodeficiency virus-protease inhibitor nelfinavir mesylate.
Lillibridge JH; Liang BH; Kerr BM; Webber S; Quart B; Shetty BV; Lee CA
Drug Metab Dispos; 1998 Jul; 26(7):609-16. PubMed ID: 9660842
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
